公开(公告)号：US08805534B2

公开(公告)日：2014-08-12

申请号：US13264093

申请日：2010-04-28

申请人： James M. Olsen ,  Michael R. Klardie ,  Richard T. Stone ,  Chad Q. Cai ,  Spencer M. Bondhus ,  Mark J. Conroy ,  Timothy R. Abraham

发明人： James M. Olsen ,  Michael R. Klardie ,  Richard T. Stone ,  Chad Q. Cai ,  Spencer M. Bondhus ,  Mark J. Conroy ,  Timothy R. Abraham

IPC分类号： A61N1/05

CPC分类号： A61N1/08 ,  A61B90/39 ,  A61B2090/3966 ,  A61N1/05 ,  A61N1/0551 ,  A61N1/086 ,  A61N1/3718 ,  A61N1/3752 ,  A61N2001/058 ,  A61N2001/0582 ,  A61N2001/086 ,  Y10T29/49016 ,  Y10T29/49117 ,  Y10T29/4921 ,  Y10T29/49227 ,  Y10T29/49826

摘要： Grounding of a shield that is located in an implantable medical lead may be done in many ways. The shield may be grounded directly to tissue from the lead body at one or more points along the lead body. The pathway for grounding may be a direct current pathway or be capacitively coupled. The pathway for grounding may utilize an exposed or nearly exposed shield at one or more points along the lead body. A jacket forming the lead body may have an outer layer removed at these points to provide the RF pathway to ground. Alternatively, the jacket may be doped with conductive particles at these points. Metal conductors such as ring electrodes and/or lead anchors may be attached to the lead at one or more points to provide the RF pathway to ground.

摘要翻译： 位于植入式医疗引线中的护罩的接地可以以许多方式进行。 屏蔽件可以沿着引线主体的一个或多个点从引线体直接接地到组织。 用于接地的途径可以是直流电路或电容耦合。 用于接地的路径可以沿着引线主体在一个或多个点处利用暴露或几乎暴露的屏蔽。 形成引线体的护套可以在这些点处具有去除的外层，以将RF通路提供到地面。 或者，夹套可以在这些点处掺杂导电颗粒。 诸如环形电极和/或引线锚的金属导体可以在一个或多个点附接到引线，以将RF通路提供到地。

公开(公告)号：US08788061B2

公开(公告)日：2014-07-22

申请号：US13265313

申请日：2010-04-27

申请人： Bruce R. Mehdizadeh ,  Brian T. Stolz ,  Michael R. Klardie ,  Michael J. Kern ,  James M. Olsen ,  Richard T. Stone ,  Chad Q. Cai ,  Spencer M. Bondhus ,  Mark J. Conroy ,  Timothy R. Abraham

发明人： Bruce R. Mehdizadeh ,  Brian T. Stolz ,  Michael R. Klardie ,  Michael J. Kern ,  James M. Olsen ,  Richard T. Stone ,  Chad Q. Cai ,  Spencer M. Bondhus ,  Mark J. Conroy ,  Timothy R. Abraham

IPC分类号： A61N1/05

CPC分类号： A61N1/056 ,  A61B90/39 ,  A61N1/086 ,  A61N1/3718 ,  A61N1/3752 ,  A61N2001/058 ,  A61N2001/0582

摘要： A shield located within an implantable medical lead may be terminated in various ways at a metal connector. The shield may be terminated by various joints including butt, scarf, lap, or other joints between insulation layers surrounding the lead and an insulation extension. The shield may terminate with a physical and electrical connection to a single metal connector. The shield may terminate with a physical and electrical connection by passing between an overlapping pair of inner and outer metal connectors. The metal connectors may include features such as teeth or threads that penetrate the insulation layers of the lead. The shield may terminate with a physical and electrical connection by exiting a jacket of a lead adjacent to a metal connector and lapping onto the metal connector.

摘要翻译： 位于可植入医疗引线内的护罩可以以各种方式在金属连接器处终止。 屏蔽层可以由围绕引线的绝缘层和绝缘延伸部之间的各种接头（包括对接，围巾，搭接或其他接头）终止。 屏蔽可以通过与单个金属连接器的物理和电连接终止。 屏蔽可以通过在重叠的一对内部和外部金属连接器之间通过物理和电连接终止。 金属连接器可以包括贯穿引线的绝缘层的诸如齿或螺纹的特征。 通过离开与金属连接器相邻的引线的护套并且研磨到金属连接器上，屏蔽件可以通过物理和电连接终止。

公开(公告)号：US20120046722A1

公开(公告)日：2012-02-23

申请号：US13264067

申请日：2010-04-27

申请人： James M. Olsen ,  Michael R. Klardie ,  Richard T. Stone ,  Chad Q. Cai ,  Spencer M. Bondhus ,  Mark J. Conroy ,  Timothy R. Abraham

发明人： James M. Olsen ,  Michael R. Klardie ,  Richard T. Stone ,  Chad Q. Cai ,  Spencer M. Bondhus ,  Mark J. Conroy ,  Timothy R. Abraham

IPC分类号： A61N1/05 ,  H01R43/00

CPC分类号： A61N1/08 ,  A61B90/39 ,  A61B2090/3966 ,  A61N1/05 ,  A61N1/0551 ,  A61N1/086 ,  A61N1/3718 ,  A61N1/3752 ,  A61N2001/058 ,  A61N2001/0582 ,  A61N2001/086 ,  Y10T29/49016 ,  Y10T29/49117 ,  Y10T29/4921 ,  Y10T29/49227 ,  Y10T29/49826

摘要： Implantable medical leads are shielded with a braided shield that surrounds an inner layer of insulation. An outer layer of insulation may also surround the shield. The shield is designed with parameters that limit the passage of radio frequency energy, particularly in the magnetic resonance imaging spectrum, to filars that are surrounded by the inner layer of insulation. The braided shield has a plurality of parameters and corresponding ranges. The parameters include one or more of braid angle, wire size, number of wires wound per direction, number of wires in a bundle, wire spacing in an axial dimension, ultimate tensile strength, cross-sectional wire shape, material, and distance from termination to a nearest electrode. Additional parameters of the lead related to the shielding also include one or more of inner insulation thickness, and outer insulation thickness.

摘要翻译： 可植入的医用引线用围绕绝缘层内层的编织屏蔽屏蔽。 绝缘外层也可围绕屏蔽。 屏蔽设计有限制射频能量通过的参数，特别是在磁共振成像光谱中，由绝缘层内层包围的丝束。 编织屏蔽具有多个参数和相应的范围。 这些参数包括一个或多个编织角度，线径，每个方向缠绕的线数，束中的线数，轴向尺寸的线间距，极限拉伸强度，截面线形状，材料和距离终止 到最近的电极。 与屏蔽相关的引线的附加参数还包括内绝缘厚度和外绝缘厚度中的一个或多个。

公开(公告)号：US20120035616A1

公开(公告)日：2012-02-09

申请号：US13264013

申请日：2010-04-27

申请人： James M. Olsen ,  Michael R. Klardie ,  Richard T. Stone ,  Chad Q. Cai ,  Spencer M. Boudhus ,  Mark J. Conway ,  Timothy R. Abraham

发明人： James M. Olsen ,  Michael R. Klardie ,  Richard T. Stone ,  Chad Q. Cai ,  Spencer M. Boudhus ,  Mark J. Conway ,  Timothy R. Abraham

IPC分类号： A61B19/00

CPC分类号： A61N1/08 ,  A61B90/39 ,  A61B2090/3966 ,  A61N1/05 ,  A61N1/0551 ,  A61N1/086 ,  A61N1/3718 ,  A61N1/3752 ,  A61N2001/058 ,  A61N2001/0582 ,  A61N2001/086 ,  Y10T29/49016 ,  Y10T29/49117 ,  Y10T29/4921 ,  Y10T29/49227 ,  Y10T29/49826

摘要： An implantable medical lead has a torsional stiffness and is rotationally coupled to a stylet. Applying rotation directly to the lead in turn causes rotation of the stylet. Where the stylet has a bent tip for purposes of steering the lead, the rotation applied to the lead rotates the bent tip so that the lead can be steered by rotating the lead rather than rotating a hub of the stylet. The rotational coupling may be achieved through one or more features provided for the lead and/or the stylet, such as a feature within a lumen of the lead that mates to a feature along the stylet or a feature of the stylet hub that engages the proximal end of the lead. The torsional stiffness of the lead may be provided by adding a feature within the lead body, such as a braided metal wire or an overlapping foil.

摘要翻译： 可植入的医用引线具有扭转刚度并旋转地联接到探针。 直接将旋转直接引导到引线，从而导致探针的转动。 探针为了转向引导而弯曲的尖端的位置，施加到引线的旋转使弯曲的尖端旋转，从而通过旋转引线而不是旋转探针的轮毂来引导引导。 旋转联接可以通过为引线和/或探针提供的一个或多个特征来实现，例如引线的内腔内的特征，其与沿着探针的特征相配合，或者与通过尖端 领先的结束。 引线的扭转刚度可以通过在引线体内添加特征来提供，例如编织金属线或重叠箔。

公开(公告)号：US10035014B2

公开(公告)日：2018-07-31

申请号：US13264013

申请日：2010-04-27

申请人： James M. Olsen ,  Michael R. Klardie ,  Richard T. Stone ,  Chad Q. Cai ,  Spencer M. Bondhus ,  Mark J. Conway ,  Timothy R. Abraham

发明人： James M. Olsen ,  Michael R. Klardie ,  Richard T. Stone ,  Chad Q. Cai ,  Spencer M. Bondhus ,  Mark J. Conway ,  Timothy R. Abraham

IPC分类号： A61N1/05 ,  A61N1/08 ,  A61N1/37 ,  A61N1/375 ,  A61B90/00

CPC分类号： A61N1/08 ,  A61B90/39 ,  A61B2090/3966 ,  A61N1/05 ,  A61N1/0551 ,  A61N1/086 ,  A61N1/3718 ,  A61N1/3752 ,  A61N2001/058 ,  A61N2001/0582 ,  Y10T29/49016 ,  Y10T29/49117 ,  Y10T29/4921 ,  Y10T29/49227 ,  Y10T29/49826

摘要： An implantable medical lead has a torsional stiffness and is rotationally coupled to a stylet. Applying rotation directly to the lead in turn causes rotation of the stylet. Where the stylet has a bent tip for purposes of steering the lead, the rotation applied to the lead rotates the bent tip so that the lead can be steered by rotating the lead rather than rotating a hub of the stylet. The rotational coupling may be achieved through one or more features provided for the lead and/or the stylet, such as a feature within a lumen of the lead that mates to a feature along the stylet or a feature of the stylet hub that engages the proximal end of the lead. The torsional stiffness of the lead may be provided by adding a feature within the lead body, such as a braided metal wire or an overlapping foil.

公开(公告)号：US08712540B2

公开(公告)日：2014-04-29

申请号：US12626374

申请日：2009-11-25

申请人： Hrishikesh Gadagkar ,  James Zimmerman ,  James M. Olsen ,  Robyn L. Jagler ,  Timothy R. Abraham ,  Jeffrey R. Dixon

发明人： Hrishikesh Gadagkar ,  James Zimmerman ,  James M. Olsen ,  Robyn L. Jagler ,  Timothy R. Abraham ,  Jeffrey R. Dixon

IPC分类号： A61N1/00

CPC分类号： A61N1/37264 ,  A61B5/055 ,  A61N1/086 ,  A61N1/3718 ,  A61N1/372 ,  A61N1/37247 ,  A61N1/37258 ,  A61N1/37282 ,  A61N1/3925 ,  G01R33/285 ,  G01R33/288 ,  G06F19/00 ,  G16H40/40

摘要： A system may include an active implantable medical device implantable in a body of a patient and a patient programmer for the AIMD. The patient programmer may be configured to obtain magnetic resonance imaging (MRI) compatibility information relating to compatibility of the AIMD with an MRI modality.

摘要翻译： 系统可以包括可植入患者体内的有源可植入医疗装置和用于AIMD的患者编程器。 患者程序员可被配置为获得与AIMD与MRI模态的兼容性相关的磁共振成像（MRI）兼容性信息。

公开(公告)号：US20120130461A1

公开(公告)日：2012-05-24

申请号：US13265283

申请日：2010-04-28

申请人： James M. Olsen ,  Michael R. Klardie ,  Richard T. Stone ,  Chad Q. Cai ,  Spencer M. Bondhus ,  Mark J. Conroy ,  Timothy R. Abraham ,  Bruce R. Mehdizadeh ,  Michael J. Kern ,  Jay K. Lahti

发明人： James M. Olsen ,  Michael R. Klardie ,  Richard T. Stone ,  Chad Q. Cai ,  Spencer M. Bondhus ,  Mark J. Conroy ,  Timothy R. Abraham ,  Bruce R. Mehdizadeh ,  Michael J. Kern ,  Jay K. Lahti

IPC分类号： A61N1/05

CPC分类号： A61N1/08 ,  A61B90/39 ,  A61B2090/3966 ,  A61N1/05 ,  A61N1/0551 ,  A61N1/086 ,  A61N1/3718 ,  A61N1/3752 ,  A61N2001/058 ,  A61N2001/0582 ,  A61N2001/086 ,  Y10T29/49016 ,  Y10T29/49117 ,  Y10T29/4921 ,  Y10T29/49227 ,  Y10T29/49826

摘要： Radiopaque markers represent that a lead is suitable for a particular medical procedure such as a magnetic resonance image scan and are added to the lead or related device. The markers may be added after implantation of the lead in various ways including suturing, gluing, crimping, or clamping a radiopaque tag to the lead or to the device. The markers may be added by placing a radiopaque coil about the lead, and the radiopaque coil may radially contract against the lead to obtain a fixed position. The markers may be added by placing a polymer structure onto the lead where the polymer structure includes a radiopaque marker within it. The polymer structure may include a cylindrical aperture that contracts against the lead to fix the position of the structure. The polymer structure may form a lead anchor that includes suture wings that can be sutured to the lead.

摘要翻译： 不透射线标记表示引线适用于特定的医学过程，例如磁共振图像扫描，并且被添加到引线或相关器件。 可以以各种方式植入引线之后添加标记物，包括缝合，胶合，卷曲或夹紧不透射线标签到引线或器件。 可以通过在引线周围放置不透射线的线圈来添加标记，并且不透射线圈可以径向地与引线收缩以获得固定位置。 可以通过将聚合物结构放置在引线上来添加标记，其中聚合物结构在其内包括不透射线的标记。 聚合物结构可以包括一个圆柱形的孔，该圆柱形的孔与引线收缩以固定结构的位置。 聚合物结构可以形成引线锚，其包括可以缝合到引线的缝合翼。

公开(公告)号：US20120041528A1

公开(公告)日：2012-02-16

申请号：US13265313

申请日：2010-04-27

申请人： Bruce R. Mehdizadeh ,  Brian T. Stolz ,  Michael R. Klardie ,  Michael J. Kern ,  James M. Olsen ,  Richard T. Stone ,  Chad Q. Cai ,  Spencer M. Bondhus ,  Mark J. Conroy ,  Timothy R. Abraham

发明人： Bruce R. Mehdizadeh ,  Brian T. Stolz ,  Michael R. Klardie ,  Michael J. Kern ,  James M. Olsen ,  Richard T. Stone ,  Chad Q. Cai ,  Spencer M. Bondhus ,  Mark J. Conroy ,  Timothy R. Abraham

IPC分类号： A61N1/05

CPC分类号： A61N1/056 ,  A61B90/39 ,  A61N1/086 ,  A61N1/3718 ,  A61N1/3752 ,  A61N2001/058 ,  A61N2001/0582

摘要： A shield located within an implantable medical lead may be terminated in various ways at a metal connector. The shield may be terminated by various joints including butt, scarf, lap, or other joints between insulation layers surrounding the lead and an insulation extension. The shield may terminate with a physical and electrical connection to a single metal connector. The shield may terminate with a physical and electrical connection by passing between an overlapping pair of inner and outer metal connectors. The metal connectors may include features such as teeth or threads that penetrate the insulation layers of the lead. The shield may terminate with a physical and electrical connection by exiting a jacket of a lead adjacent to a metal connector and lapping onto the metal connector.

摘要翻译： 位于可植入医疗引线内的护罩可以以各种方式在金属连接器处终止。 屏蔽层可以由围绕引线的绝缘层和绝缘延伸部之间的各种接头（包括对接，围巾，搭接或其他接头）终止。 屏蔽可以通过与单个金属连接器的物理和电连接终止。 屏蔽可以通过在重叠的一对内部和外部金属连接器之间通过物理和电连接终止。 金属连接器可以包括贯穿引线的绝缘层的诸如齿或螺纹的特征。 通过离开与金属连接器相邻的引线的护套并且研磨到金属连接器上，屏蔽件可以通过物理和电连接终止。

公开(公告)号：US20120035694A1

公开(公告)日：2012-02-09

申请号：US13264093

申请日：2010-04-28

申请人： James M. Olsen ,  Michael R. Klardie ,  Richard T. Stone ,  Chad Q Cai ,  Spencer M. Bondhus ,  Mark J. Conroy ,  Timothy R. Abraham

发明人： James M. Olsen ,  Michael R. Klardie ,  Richard T. Stone ,  Chad Q Cai ,  Spencer M. Bondhus ,  Mark J. Conroy ,  Timothy R. Abraham

IPC分类号： A61N1/05 ,  H01R43/00

CPC分类号： A61N1/08 ,  A61B90/39 ,  A61B2090/3966 ,  A61N1/05 ,  A61N1/0551 ,  A61N1/086 ,  A61N1/3718 ,  A61N1/3752 ,  A61N2001/058 ,  A61N2001/0582 ,  A61N2001/086 ,  Y10T29/49016 ,  Y10T29/49117 ,  Y10T29/4921 ,  Y10T29/49227 ,  Y10T29/49826

摘要： Grounding of a shield that is located in an implantable medical lead may be done in many ways. The shield may be grounded directly to tissue from the lead body at one or more points along the lead body. The pathway for grounding may be a direct current pathway or be capacitively coupled. The pathway for grounding may utilize an exposed or nearly exposed shield at one or more points along the lead body. A jacket forming the lead body may have an outer layer removed at these points to provide the RF pathway to ground. Alternatively, the jacket may be doped with conductive particles at these points. Metal conductors such as ring electrodes and/or lead anchors may be attached to the lead at one or more points to provide the RF pathway to ground.

摘要翻译： 位于植入式医疗引线中的护罩的接地可以以许多方式进行。 屏蔽件可以沿着引线主体的一个或多个点从引线体直接接地到组织。 用于接地的途径可以是直流电路或电容耦合。 用于接地的路径可以沿着引线主体在一个或多个点处利用暴露或几乎暴露的屏蔽。 形成引线体的护套可以在这些点处具有去除的外层，以将RF通路提供到地面。 或者，夹套可以在这些点处掺杂导电颗粒。 诸如环形电极和/或引线锚的金属导体可以在一个或多个点附接到引线，以将RF通路提供到地。

公开(公告)号：US10086194B2

公开(公告)日：2018-10-02

申请号：US13264179

申请日：2010-04-27

申请人： Michael J. Kern ,  James M. Olsen ,  Michael R. Klardie ,  Richard T. Stone ,  Chad Q. Cai ,  Spencer M. Bondhus ,  Mark J. Conroy ,  Timothy R. Abraham ,  Brian T. Stolz

发明人： Michael J. Kern ,  James M. Olsen ,  Michael R. Klardie ,  Richard T. Stone ,  Chad Q. Cai ,  Spencer M. Bondhus ,  Mark J. Conroy ,  Timothy R. Abraham ,  Brian T. Stolz

IPC分类号： A61N1/05 ,  A61N1/08 ,  A61N1/37 ,  A61N1/375 ,  A61B90/00

摘要： A shield located within an implantable medical lead may be terminated in various ways. The shield may be terminated by butt, scarf, lap, or other joints between insulation layers surrounding the lead and an insulation extension. For lap joints, a portion of an outer insulation layer may be removed and a replacement outer insulation layer is positioned in place of the removed outer insulation layer, where the replacement layer extends beyond an inner insulation layer and the shield. The replacement layer may also lap onto a portion of the insulation extension. Barbs may be located between the replacement layer and the inner insulation layer or the insulation extension. The shield wires have ends at the termination point that may be folded over individually or may be capped with a ring located within one of the insulation layers of the jacket.