Methods and means related to cancer stem cells

    公开(公告)号:US10538742B2

    公开(公告)日:2020-01-21

    申请号:US11667819

    申请日:2005-11-12

    Applicant: Toru Kondo

    Inventor: Toru Kondo

    Abstract: This invention relates to the methods for the identification and isolation of cancer stem cells from cultured cancer cell lines. Cell line-derived cancer stem cells isolated using the present methods may be useful, for example, in assays to screen compounds for anti-cancer stem cell activity and in target discovery methods for identifying novel expressed genes and druggable targets. The invention also relates to the screening of compounds for activity against cell line-derived cancer stem cells.

    Vehicle instrument panel
    2.
    发明授权
    Vehicle instrument panel 有权
    车载仪表板

    公开(公告)号:US08821225B2

    公开(公告)日:2014-09-02

    申请号:US13635767

    申请日:2010-03-19

    CPC classification number: B60H1/00564 B60H1/0055 B60H1/242

    Abstract: Condensation is suppressed from developing on a front face of an instrument panel main body. A instrument panel of the present invention is configured including: an instrument panel main body formed with a center air conditioning outlet and a center defroster outlet; a first panel that is joined to the instrument panel main body and is formed with a top side wall section that configures the vehicle top-bottom direction top side of a center air conditioning duct and a first wall section that configures part of a center defroster duct; and a second panel that is joined to the instrument panel main body and is formed with a bottom side wall section that configures the center air conditioning duct in combination with the top side wall section and a second wall section that configures the center defroster duct in combination with the first wall section.

    Abstract translation: 抑制了在仪表板主体的正面上显影的凝结。 本发明的仪表板包括:仪表板主体,形成有中央空调出口和中央除霜器出口; 第一面板,其接合到仪表板主体,并且形成有构造中央空调管道的车辆上下方向上侧的顶侧壁部和构成中央除霜器管道的一部分的第一壁部 ; 以及第二面板,其接合到仪表板主体,并且形成有底壁部分,其将中心空调管道与顶侧壁部分组合;以及第二壁部分,其组合中心除霜器管道 与第一个墙段。

    Solid-state imaging device
    3.
    发明授权
    Solid-state imaging device 有权
    固态成像装置

    公开(公告)号:US08299414B2

    公开(公告)日:2012-10-30

    申请号:US12643354

    申请日:2009-12-21

    Applicant: Toru Kondo

    Inventor: Toru Kondo

    CPC classification number: H04N5/347 H04N5/343 H04N5/3742

    Abstract: A solid-state imaging device comprises pixel units, column signal lines, column circuits, a switching unit, and a mode control unit. Pixel units are two-dimensionally disposed in a matrix direction, and each of them comprises a photoelectric conversion unit and an amplifying unit. Column signal lines are provided for each column and the pixel signals from the amplifying units are output to each of rows. Column circuits are provided for each column and process signals from the column signal lines. A switching unit switches connection between the column signal lines and the column circuits. A mode control unit outputs signals to the switching unit and controls switching between a first mode in which the column signal lines are connected to the column circuits on the same column thereof and a second mode in which the column signal lines are connected to the column circuits on another column.

    Abstract translation: 固态成像装置包括像素单元,列信号线,列电路,开关单元和模式控制单元。 像素单元在矩阵方向上二维地设置,并且每个单元包括光电转换单元和放大单元。 为每列提供列信号线,并且来自放大单元的像素信号被输出到每行。 为每列提供列电路,并处理来自列信号线的信号。 切换单元切换列信号线和列电路之间的连接。 模式控制单元向切换单元输出信号,并且控制列列信号线与其同一列上的列电路连接的第一模式和列信号线连接到列电路的第二模式之间的切换 在另一列。

    Solid-state imaging apparatus
    4.
    发明授权
    Solid-state imaging apparatus 有权
    固态成像装置

    公开(公告)号:US08184185B2

    公开(公告)日:2012-05-22

    申请号:US12482832

    申请日:2009-06-11

    Applicant: Toru Kondo

    Inventor: Toru Kondo

    CPC classification number: H04N5/3575 H04N5/3658 H04N5/378

    Abstract: A solid-state imaging apparatus including: a pixel section having a plurality of pixels arranged into two dimensions for converting an incident light into a signal electric charge and for outputting an electrical signal corresponding to the signal electric charge; vertical signal lines for reading the signals of the pixel section column by column; a horizontal signal line for reading the signals through switches from the vertical signal lines; and a variable amplification section for reading the signal from the horizontal signal line with amplifying it by a predetermined amplification factor, and further includes a control section for effecting a control so that a signal level on the horizontal signal line does not exceed a predetermined limit level when signals are read out from the vertical signal lines to the horizontal signal line.

    Abstract translation: 一种固态成像装置,包括:像素部分,具有排列成二维的多个像素,用于将入射光转换为信号电荷并输出对应于信号电荷的电信号; 用于逐列读取像素部分的信号的垂直信号线; 用于从垂直信号线读出通过开关的信号的水平信号线; 以及可变放大部分,用于以预定的放大系数对来自水平信号线的信号进行放大,并且还包括用于进行控制的控制部分,使得水平信号线上的信号电平不超过预定限制电平 当信号从垂直信号线读出到水平信号线时。

    SOLID-STATE IMAGE PICKUP APPARATUS AND SOLID-STATE IMAGE PICKUP METHOD
    5.
    发明申请
    SOLID-STATE IMAGE PICKUP APPARATUS AND SOLID-STATE IMAGE PICKUP METHOD 有权
    固态图像拾取装置和固态图像拾取方法

    公开(公告)号:US20100103302A1

    公开(公告)日:2010-04-29

    申请号:US12607353

    申请日:2009-10-28

    Applicant: Toru Kondo

    Inventor: Toru Kondo

    CPC classification number: H04N5/3456 H04N5/378

    Abstract: A solid-state image pickup apparatus comprising a pixel section which comprises a plurality of unit pixels which are arranged in a matrix, and converts an input optical signal to an electric signal, a column circuit which processes the electric signal which is outputted from the pixel section column by column, and a column circuit current controlling section which reduces current of column circuit, whose electric signal is not read out, than current of column circuit whose electric signal is read out, when a first mode which thins out and reads out electric signals of column circuits is set.

    Abstract translation: 一种固态图像拾取装置,包括像素部分,其包括以矩阵布置的多个单位像素,并将输入的光信号转换为电信号;列电路,其处理从像素输出的电信号 以及列电路电流控制部,其将电信号未读出的列电路的电流与读出电信号的列电路的电流相比较,当第一模式切换并读出电 列电路的信号被置位。

    CAMERA SYSTEM
    6.
    发明申请
    CAMERA SYSTEM 有权
    相机系统

    公开(公告)号:US20080018761A1

    公开(公告)日:2008-01-24

    申请号:US11779614

    申请日:2007-07-18

    CPC classification number: H04N5/2353 H04N5/238 H04N5/353 H04N5/359

    Abstract: A camera system at least including: a MOS imaging device at least having a pixel section having a plurality of pixels two-dimensionally arrayed in row and column directions, each having a photoelectric conversion section for generating electrical signal corresponding to a quantity of incident light, an accumulation section for accumulating signal generated at the photoelectric conversion section, a transfer switch means for controlling transfer of signal from the photoelectric conversion section to the accumulation section, a reset switch means for resetting signal of the photoelectric conversion section, an amplification section for outputting a voltage value corresponding to signal of the accumulation section, and a select switch for selecting output of the amplification section, wherein an exposure period is determined by simultaneously resetting signals of the photoelectric conversion section for all pixels and effecting signal transfer from the photoelectric conversion section to the accumulation section after a predetermined time, and readout of signal from the pixels is sequentially effected at later time; and an incident light quantity suppressing means for suppressing the quantity of light incident to the MOS imaging device during read operation of signal from each pixel of the MOS imaging device.

    Abstract translation: 一种照相机系统,至少包括:MOS成像装置,其至少具有像素部分,所述像素部分具有在行和列方向上二维排列的多个像素,每个像素部分具有用于产生对应于入射光量的电信号的光电转换部分, 用于累积在光电转换部分产生的信号的累积部分,用于控制从光电转换部分到累积部分的信号传送的转移开关装置,用于复位光电转换部分的信号的复位开关装置,用于输出光电转换部分的放大部分 对应于累积部分的信号的电压值和用于选择放大部分的输出的选择开关,其中通过对所有像素同时复位光电转换部分的信号并且从光电转换部分进行信号传输来确定曝光周期 至 在预定时间之后的累积部分和来自像素的信号的读出在稍后的时间顺序地进行; 以及入射光量抑制装置,用于抑制在来自MOS成像装置的每个像素的信号的读取操作期间入射到MOS成像装置的光量。

    Signal transmission circuit
    7.
    发明申请
    Signal transmission circuit 有权
    信号传输电路

    公开(公告)号:US20050184763A1

    公开(公告)日:2005-08-25

    申请号:US11054957

    申请日:2005-02-11

    Applicant: Toru Kondo

    Inventor: Toru Kondo

    CPC classification number: H03K5/15013 G11C19/00 G11C19/18

    Abstract: The signal transmission circuit comprises a first switch controls output according to a first control pulse, the first source follower outputting signals to the first output line based on signal input into the gate, a first capacitor connected between the gate and the source of the source follower, the first circuit, based on a level of the input signal, fixing the first output line to reference potential, the second switch controlling output according to a second control pulse, the second source follower, according to signals input into the gate, supplying output signals to the subsequent stage and also to a second output line, a second capacitor connected between the gate and the source of the source follower, and the second circuit, based on a level of input signals from the source, fixing the second output line to reference potential.

    Abstract translation: 所述信号传输电路包括第一开关,根据第一控制脉冲控制输出,所述第一源极跟随器根据输入到所述栅极的信号将信号输出到所述第一输出线,所述第一电容器连接在所述源极跟随器的栅极和源极之间 所述第一电路基于所述输入信号的电平,将所述第一输出线固定为参考电位,所述第二开关根据第二控制脉冲控制输出,所述第二源极跟随器根据输入到所述栅极的信号,提供输出 信号到后一级,并且还连接到第二输出线,连接在源极跟随器的栅极和源极之间的第二电容器和第二电路,基于来自源极的输入信号的电平,将第二输出线固定到 参考潜力。

    Solid-state image pickup apparatus and solid-state image pickup method to reduce power consumption
    8.
    发明授权
    Solid-state image pickup apparatus and solid-state image pickup method to reduce power consumption 有权
    固态摄像装置和固态摄像方式降低功耗

    公开(公告)号:US08743255B2

    公开(公告)日:2014-06-03

    申请号:US12607353

    申请日:2009-10-28

    Applicant: Toru Kondo

    Inventor: Toru Kondo

    CPC classification number: H04N5/3456 H04N5/378

    Abstract: A solid-state image pickup apparatus including a pixel section, a column circuit, and a column circuit controlling section. The pixel section includes a plurality of unit pixels arranged in a matrix and converts an input optical signal to an electric signal. The column circuit processes the electric signal which is outputted from the pixel section column by column. The column circuit current controlling section reduces current of the column circuit, whose electric signal is not read out, than current of column circuit whose electric signal is read out, when a first mode which thins out and reads out electric signals of column circuits is set.

    Abstract translation: 一种固态图像拾取装置,包括像素部分,列电路和列电路控制部分。 像素部分包括以矩阵排列的多个单位像素,并将输入的光信号转换为电信号。 列电路逐列地处理从像素部输出的电信号。 在设置了读出列电路的电信号的第一模式时,列电路电流控制部将电信号未读出的列电路的电流与读出电信号的列电路的电流相比较 。

    Solid-state imaging apparatus
    9.
    发明授权
    Solid-state imaging apparatus 有权
    固态成像装置

    公开(公告)号:US08659682B2

    公开(公告)日:2014-02-25

    申请号:US12475021

    申请日:2009-05-29

    CPC classification number: H04N5/3651 H04N5/3742 H04N5/3745 H04N5/378

    Abstract: A solid-state imaging apparatus including: a pixel section having pixels two-dimensionally arranged into rows and columns each pixel containing a photoelectric converter, an amplifier for amplifying and outputting as pixel signal a signal electric charge of the photoelectric converter, and a reset circuit for resetting signal electric charges accumulated at the amplifier; a vertical scanning section for selecting a row to be read out of the pixel section; a vertical signal line provided column by column for outputting the signal from the pixel section; and a sample-and-hold type bias section connected to the vertical signal line containing at least a hold circuit for setting an electric current flowing into the amplifier. The sample-and-hold type bias section causes to generate an electric current corresponding to a voltage set at the hold circuit when signal electric charges accumulated at the photoelectric converter is read out from the amplifier.

    Abstract translation: 一种固态成像装置,包括:具有二维排列成包含光电转换器的像素的行和列的像素的像素部,放大并输出作为光电转换器的信号电荷的像素信号的放大器,以及复位电路 用于复位在放大器处累积的信号电荷; 垂直扫描部分,用于选择要从像素部分读出的行; 逐列设置的垂直信号线,用于从像素部输出信号; 以及连接到垂直信号线的采样保持型偏置部分,至少包含用于设置流入放大器的电流的保持电路。 当从放大器读出在光电转换器处累积的信号电荷时,采样保持型偏置部分产生与保持电路设置的电压相对应的电流。

    Solid-state imaging apparatus having multiple channel output
    10.
    发明授权
    Solid-state imaging apparatus having multiple channel output 有权
    具有多通道输出的固态成像装置

    公开(公告)号:US08059172B2

    公开(公告)日:2011-11-15

    申请号:US11790944

    申请日:2007-04-30

    Applicant: Toru Kondo

    Inventor: Toru Kondo

    CPC classification number: H04N5/225 H04N5/217 H04N5/335 H04N5/357 H04N5/369

    Abstract: A solid-state imaging apparatus of the present invention including: a pixel section having pixels two-dimensionally disposed in a row and column directions each containing a photoelectric conversion section and an amplification section for amplifying and outputting as pixel signal an output of the photoelectric conversion section; a first scanning section for selecting rows to be read of the pixel section; a noise suppressing section for effecting noise suppression of the pixel signals; a second scanning section for causing pixel signals having gone through the noise suppressing section to be outputted from a plurality of horizontal signal lines; and a control section having a plurality of drive modes to be set, different in the number of the horizontal signal lines from which the pixel signals are outputted, and, when a drive mode is set, changing in accordance with the set drive mode the manner of connection of a function device within the noise suppressing section associated with the horizontal signal lines pertinent to the drive mode.

    Abstract translation: 本发明的固态成像装置包括:像素部分,具有二维地排列成行和列方向的像素,每个像素部分包含光电转换部分和放大部分,用于放大和输出作为光电转换的输出的像素信号 部分; 用于选择要被读取的像素部分的行的第一扫描部分; 用于对像素信号进行噪声抑制的噪声抑制部分; 第二扫描部分,用于使经过噪声抑制部分的像素信号从多个水平信号线输出; 以及控制部,其具有要设置的多个驱动模式的多个驱动模式,其中输出像素信号的水平信号线的数量不同,并且当设置驱动模式时,根据设定的驱动模式改变方式 功能器件与与驱动模式相关的水平信号线相关联的噪声抑制部分内的连接。

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