Abstract:
This invention relates to the methods for the identification and isolation of cancer stem cells from cultured cancer cell lines. Cell line-derived cancer stem cells isolated using the present methods may be useful, for example, in assays to screen compounds for anti-cancer stem cell activity and in target discovery methods for identifying novel expressed genes and druggable targets. The invention also relates to the screening of compounds for activity against cell line-derived cancer stem cells.
Abstract:
Condensation is suppressed from developing on a front face of an instrument panel main body. A instrument panel of the present invention is configured including: an instrument panel main body formed with a center air conditioning outlet and a center defroster outlet; a first panel that is joined to the instrument panel main body and is formed with a top side wall section that configures the vehicle top-bottom direction top side of a center air conditioning duct and a first wall section that configures part of a center defroster duct; and a second panel that is joined to the instrument panel main body and is formed with a bottom side wall section that configures the center air conditioning duct in combination with the top side wall section and a second wall section that configures the center defroster duct in combination with the first wall section.
Abstract:
A solid-state imaging device comprises pixel units, column signal lines, column circuits, a switching unit, and a mode control unit. Pixel units are two-dimensionally disposed in a matrix direction, and each of them comprises a photoelectric conversion unit and an amplifying unit. Column signal lines are provided for each column and the pixel signals from the amplifying units are output to each of rows. Column circuits are provided for each column and process signals from the column signal lines. A switching unit switches connection between the column signal lines and the column circuits. A mode control unit outputs signals to the switching unit and controls switching between a first mode in which the column signal lines are connected to the column circuits on the same column thereof and a second mode in which the column signal lines are connected to the column circuits on another column.
Abstract:
A solid-state imaging apparatus including: a pixel section having a plurality of pixels arranged into two dimensions for converting an incident light into a signal electric charge and for outputting an electrical signal corresponding to the signal electric charge; vertical signal lines for reading the signals of the pixel section column by column; a horizontal signal line for reading the signals through switches from the vertical signal lines; and a variable amplification section for reading the signal from the horizontal signal line with amplifying it by a predetermined amplification factor, and further includes a control section for effecting a control so that a signal level on the horizontal signal line does not exceed a predetermined limit level when signals are read out from the vertical signal lines to the horizontal signal line.
Abstract:
A solid-state image pickup apparatus comprising a pixel section which comprises a plurality of unit pixels which are arranged in a matrix, and converts an input optical signal to an electric signal, a column circuit which processes the electric signal which is outputted from the pixel section column by column, and a column circuit current controlling section which reduces current of column circuit, whose electric signal is not read out, than current of column circuit whose electric signal is read out, when a first mode which thins out and reads out electric signals of column circuits is set.
Abstract:
A camera system at least including: a MOS imaging device at least having a pixel section having a plurality of pixels two-dimensionally arrayed in row and column directions, each having a photoelectric conversion section for generating electrical signal corresponding to a quantity of incident light, an accumulation section for accumulating signal generated at the photoelectric conversion section, a transfer switch means for controlling transfer of signal from the photoelectric conversion section to the accumulation section, a reset switch means for resetting signal of the photoelectric conversion section, an amplification section for outputting a voltage value corresponding to signal of the accumulation section, and a select switch for selecting output of the amplification section, wherein an exposure period is determined by simultaneously resetting signals of the photoelectric conversion section for all pixels and effecting signal transfer from the photoelectric conversion section to the accumulation section after a predetermined time, and readout of signal from the pixels is sequentially effected at later time; and an incident light quantity suppressing means for suppressing the quantity of light incident to the MOS imaging device during read operation of signal from each pixel of the MOS imaging device.
Abstract:
The signal transmission circuit comprises a first switch controls output according to a first control pulse, the first source follower outputting signals to the first output line based on signal input into the gate, a first capacitor connected between the gate and the source of the source follower, the first circuit, based on a level of the input signal, fixing the first output line to reference potential, the second switch controlling output according to a second control pulse, the second source follower, according to signals input into the gate, supplying output signals to the subsequent stage and also to a second output line, a second capacitor connected between the gate and the source of the source follower, and the second circuit, based on a level of input signals from the source, fixing the second output line to reference potential.
Abstract:
A solid-state image pickup apparatus including a pixel section, a column circuit, and a column circuit controlling section. The pixel section includes a plurality of unit pixels arranged in a matrix and converts an input optical signal to an electric signal. The column circuit processes the electric signal which is outputted from the pixel section column by column. The column circuit current controlling section reduces current of the column circuit, whose electric signal is not read out, than current of column circuit whose electric signal is read out, when a first mode which thins out and reads out electric signals of column circuits is set.
Abstract:
A solid-state imaging apparatus including: a pixel section having pixels two-dimensionally arranged into rows and columns each pixel containing a photoelectric converter, an amplifier for amplifying and outputting as pixel signal a signal electric charge of the photoelectric converter, and a reset circuit for resetting signal electric charges accumulated at the amplifier; a vertical scanning section for selecting a row to be read out of the pixel section; a vertical signal line provided column by column for outputting the signal from the pixel section; and a sample-and-hold type bias section connected to the vertical signal line containing at least a hold circuit for setting an electric current flowing into the amplifier. The sample-and-hold type bias section causes to generate an electric current corresponding to a voltage set at the hold circuit when signal electric charges accumulated at the photoelectric converter is read out from the amplifier.
Abstract:
A solid-state imaging apparatus of the present invention including: a pixel section having pixels two-dimensionally disposed in a row and column directions each containing a photoelectric conversion section and an amplification section for amplifying and outputting as pixel signal an output of the photoelectric conversion section; a first scanning section for selecting rows to be read of the pixel section; a noise suppressing section for effecting noise suppression of the pixel signals; a second scanning section for causing pixel signals having gone through the noise suppressing section to be outputted from a plurality of horizontal signal lines; and a control section having a plurality of drive modes to be set, different in the number of the horizontal signal lines from which the pixel signals are outputted, and, when a drive mode is set, changing in accordance with the set drive mode the manner of connection of a function device within the noise suppressing section associated with the horizontal signal lines pertinent to the drive mode.