中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

26 records (took 0.013 seconds)

    Bovine vaccines and methods of making and using same
    1.
    发明授权
    Bovine vaccines and methods of making and using same 失效
    牛疫苗及其制造和使用方法

    公开(公告)号：US3925544A

    公开(公告)日：1975-12-09

    申请号：US42865873

    申请日：1973-12-27

    Applicant: UNIV SOUTHERN ILLINOIS

    Inventor： SHECHMEISTER ISAAC L ,  KOLAR JR JOSEPH R ,  KAMMLADE JR WILLIAM G

    IPC: A61K39/295 ,  A61K27/12

    CPC classification number: A61K39/12 ,  A61K39/102 ,  A61K2039/5252 ,  A61K2039/552 ,  A61K2039/55583 ,  A61K2039/70 ,  C12N2710/16734 ,  C12N2760/18634 ,  C12N2770/24334 ,  Y10S424/813

    Abstract: A polyvalent vaccine effective in immunization of bovines against infectious bovine rhinotracheitis virus (IBR), bovine viral diarrhea virus (BVD) and parainfluenza-3 virus (PI-3) is composed of a suspension, in a vehicle such as an aqueous solution of formaldehyde suitable for parenteral injection of the three viruses in killed form. The three viruses are separately propagated and subsequently suspended in aqueous solutions containing 0.4 percent by volume formalin, and the respective suspensions are maintained at a temperature of about 4*C. for 1 week. Portions, for example equal portions, of the three suspensions are combined to produce a polyvalent vaccine. An equal volume of an aqueous solution containing from 1 to 5 percent weight/volume of a soluble alginate, such as sodium alginate, having certain specified properties may be added to the vaccine as an adjuvant to enhance its effectiveness. Such polyvalent vaccines are adapted for parenteral administration in the vaccination of bovines.

    Abstract translation: 在针对感染性牛鼻气管炎病毒（IBR），牛病毒性腹泻病毒（BVD）和副流感-3病毒（PI-3）的免疫接种中有效的多价疫苗由悬浮液组成，载体如甲醛水溶液 适用于以杀死形式肠胃外注射三种病毒。 将三种病毒分开繁殖并随后悬浮于含有0.4％（体积）福尔马林的水溶液中，并将各悬浮液保持在约4℃的温度下1周。 将三个悬浮液的部分例如相等的部分组合以产生多价疫苗。 可以将等体积的含有1至5重量％体积的具有特定特性的可溶性藻酸盐如海藻酸钠的水溶液作为佐剂加入到佐剂中以增强其有效性。 这种多价疫苗适用于在牛疫苗接种中肠胃外给药。

    One-step synthesis of alpha, beta-unsaturated sulfonate salts by the reaction of carbon tetrahalides with certain sulfones
    2.
    发明授权
    One-step synthesis of alpha, beta-unsaturated sulfonate salts by the reaction of carbon tetrahalides with certain sulfones 失效
    通过碳硫化物与某些硫的反应，一步合成ALPHA，BETA不饱和磺酸盐

    公开(公告)号：US3876689A

    公开(公告)日：1975-04-08

    申请号：US28404672

    申请日：1972-08-28

    Applicant: UNIV SOUTHERN ILLINOIS

    Inventor： MEYERS CAL Y ,  HO LAURENCE L

    IPC: C07C67/00 ,  C07C301/00 ,  C07C303/02 ,  C07C303/30 ,  C07C309/20 ,  C07C309/24 ,  C07C309/29 ,  C07C309/78 ,  C07C143/00

    CPC classification number: C07C309/78 ,  C07C309/20

    Abstract: .alpha.,.beta.-Unsaturated sulfonic acid salts are prepared by a one step synthesis involving reaction of a di-primary alkyl sulfone, an arylmethyl primary alkyl sulfone, an .alpha.-halo diprimary alkyl sulfone, or an .alpha.-haloarylmethyl primary alkyl sulfone with a carbon tetrahalide and a strong base. The sulfone substrate is reacted with a carbon tetrahalide represented by the formula CBr.sub.m Cl.sub.n F.sub.p where m and n are integers between 0 and 4 inclusive, p is an integer between 0 and 2 inclusive and m+n+p = 4 in the presence of the strong base to form a geminally .alpha.-dihalogenated intermediate and dihalocarbene. The geminally .beta.-dihalogenated intermediate reacts rapidly in situ with the strong base to form an .alpha.,.beta.-unsaturated sulfonic acid salt and a halide salt. The unsaturated sulfonic acid salt may be acidified to form the corresponding acid or reacted with a halogenating agent to form the corresponding acid halide. .alpha.,.beta.-Unsaturated sulfonic acid salts are useful detergents.

    Portable electroanesthesia device with automatic power control
    3.
    发明授权
    Portable electroanesthesia device with automatic power control 失效
    具有自动功率控制功能的便携式电子设备

    公开(公告)号：US3791373A

    公开(公告)日：1974-02-12

    申请号：US3791373D

    申请日：1972-03-02

    Applicant: UNIV SOUTHERN ILLINOIS

    Inventor： WINKLER E ,  MC GOWAN E

    IPC: A61N1/08 ,  A61N1/34

    CPC classification number: A61N1/36021 ,  A61N1/08 ,  A61N1/378

    Abstract: A portable, battery-powered, self-contained electroanesthesia device. A signal generator provides a sinusoidal, constant magnitude signal of fixed, preset frequency with relatively high accuracy and without recalibration each time the device is energized. The preset frequency characteristically produces electroanesthetic induction in a live subject with relatively high efficiency. An amplifier increases the power level sufficiently for producing electroanesthetic induction of the subject. Electrodes supply the amplified signal to tissue of the subject, there being provision for matching the impedance of said tissue of the subject to the amplifier for maximizing transfer of the amplified signal to said tissue. Circuitry is provided also for monitoring and limiting the power level of the signal supplied by said electrodes to the tissue.

    Abstract translation: 便携式，电池供电的独立电感觉装置。 信号发生器提供具有固定的预设频率的正弦，恒定幅度信号，具有相对高的精度，并且每当器件通电时不再重新校准。 预设频率特征性地在相当高效率的活体中产生电觉感应。 放大器充分增加功率水平以产生受试者的电觉感应。 电极将放大的信号提供给受试者的组织，其中提供用于使被检体的所述组织的阻抗与放大器匹配，以使放大的信号向所述组织的传递最大化。 电路还用于监视和限制由所述电极提供给组织的信号的功率电平。

    Oxidation of carbohydrates
    4.
    发明授权
    Oxidation of carbohydrates 失效
    碳水化合物的氧化

    公开(公告)号：US3632802A

    公开(公告)日：1972-01-04

    申请号：US3632802D

    申请日：1968-12-06

    Applicant: UNIV SOUTHERN ILLINOIS

    Inventor： BEMILLER JAMES N ,  DARLING STEPHEN D

    IPC: C08B31/18

    CPC classification number: C08B31/18

    Abstract: CARBOHYDRATES SUCH AS STARCH AND CELLULOSE HAVING UNSUBSTITUTED PRIMARY HYDROXYL GROUPS ARE OXIDIZED WITH AN ALKALI METAL FERRATE, SUCH AS POTASSIUM FERRATE, TO YIELD PRODUCTS IN WHICH AT LEAST ONE OF THE PRIMARY HYDROXYL GROUPS IS CONVERTED TO AN ALDEHYDE GROUP. THE USE OF SUCH A FERRATE COMPOUND AS THE OXIDIZING AGENT PERMITS OXIDATION TO BE CARRIED OUT WITHOUT THE FORMATION OF CARBOXYL GROUPS, WITHOUT THE OXIDATION OF SECONDARY HYDROXYL GROUPS AND WITHOUT SCISSION OF CARBON TO CARBON BONDS IN THE CARBOHYDRATE MOLECULES. THE RESULTING PRODUCTS EXHIBIT IMPROVED PHYSICAL PROPERTIES AND MAY BE USED, FOR EXAMPLE, IN PAPER SIZING APPLICANTS OR AS CHEMICAL INTERMEDIATES IN THE PREPARATION OF OTHER USEFUL DERIVATIVES.

Patent Agency Ranking