Probe for optical spectroscopy
    3.
    发明授权

    公开(公告)号:US11684266B2

    公开(公告)日:2023-06-27

    申请号:US16495560

    申请日:2018-03-15

    Abstract: A probe comprising a body portion and a tip portion. The body portion comprises: a first mounting portion comprising a plurality of first carriers, each first carrier being arranged to support an elongate first waveguide, the first carriers being disposed in an equiangular arrangement around a longitudinal axis of the body portion; a plurality of first waveguides, each first waveguide being supported in a respective one of the plurality of first carriers; and a body end fitting at which first ends of the first waveguides are supported in the equiangular arrangement around the longitudinal axis of the body portion such that the first waveguides can transmit electromagnetic radiation signals from an energy source to the body end fitting and/or transmit electromagnetic radiation signals from the body end fitting to a receiver. The tip portion comprises: a second mounting portion comprising a plurality of second carriers, each second carrier being arranged to support an elongate second waveguides, the second carriers being disposed in the equiangular arrangement around a longitudinal axis of the tip portion; a plurality of second waveguides, each second waveguides being supported in a respective one of the plurality of second carriers; and a tip end fitting at which first ends of the second waveguides are supported in the equiangular arrangement around the longitudinal axis of the tip portion; and an elongate conduit for piercing human tissue.

    TEST APPARATUS
    4.
    发明申请

    公开(公告)号:US20220146426A1

    公开(公告)日:2022-05-12

    申请号:US17430565

    申请日:2020-02-12

    Abstract: A test apparatus is disclosed that has a housing containing a location at which a sample tray containing a plurality of sample wells can be located, a light box positioned to permit irradiation of the sample tray, and an imaging arrangement to permit imaging of the sample tray. The light box has a light source including a light guide in the form of a plate of a transparent material and a plurality of light emitting devices provided adjacent at least one edge of the plate where a surface of the plate is provided with a plurality of transmitting regions and light is transmitted from the plate.

    COMPOSITIONS COMPRISING INTERMEDIATE NON-CODING RNA REGULATORS MODULATING THE EXPRESSION OF ETV6 OR FOXO1 AND USES THEREOF

    公开(公告)号:US20210292765A1

    公开(公告)日:2021-09-23

    申请号:US17263465

    申请日:2019-07-29

    Abstract: The present invention relates to: compositions for modulating the expression of FOXO1 and/or ETV6, the composition comprising one or more intermediate non-coding RNA regulators; attenuating splicing factor expression, the composition comprising an expression modulator of FOXO1 and/or ETV6; attenuating cell senescence and/or re-entry to cell cycle, the composition comprising an expression modulator of FOXO1 and/or ETV6 or their downstream targets related to splicing factor expression; or a composition capable of modulating splicing factor expression, the composition comprising one or more compounds able to bind to, or inhibit, FOXO1 and/or ETV6 genes or their downstream targets related to splicing factor expression. Such compositions have therapeutic benefits in the prevention, management, amelioration or treatment of an age-related disease or condition or cancer or also as a research tool/reagent.

    ELECTRICAL GENERATION
    10.
    发明申请

    公开(公告)号:US20220158527A1

    公开(公告)日:2022-05-19

    申请号:US17600838

    申请日:2020-04-01

    Abstract: An electrical generation apparatus is described comprising a magnetic mass (18) magnetically attracted to a guide member (14) such that the mass (18) is moveable, in use, along a path defined by the shape of the outer periphery of the guide member (14), the mass (18) being moveable past a coil (20), and at least one repulsion magnet (16a, 16b) of the same polarity as the mass (18) and positioned to repel the mass (18) such that the mass (18) undertakes a pendulum-like reciprocating motion, repeatedly passing the coil.

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