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公开(公告)号:US09040237B2
公开(公告)日:2015-05-26
申请号:US11226696
申请日:2005-09-13
申请人: Tae-Woong Koo , Selena Chan , Xing Su , Zhang Jingwu , Mineo Yamakawa , Val M. Dubin
发明人: Tae-Woong Koo , Selena Chan , Xing Su , Zhang Jingwu , Mineo Yamakawa , Val M. Dubin
CPC分类号: C12Q1/6874 , B01J2219/00317 , B01J2219/00511 , B01J2219/00605 , B01J2219/00612 , B01J2219/00621 , B01J2219/00626 , B01J2219/0063 , B01J2219/00641 , B01J2219/00722 , B01L3/5085 , B82Y30/00 , C12Q1/6869 , G01N27/414 , G01N27/4145 , G01N27/4148
摘要: Embodiments of the present invention provide devices methods for sequencing DNA using arrays of reaction cavities containing sensors to monitor changes in solutions contained in the reaction cavities. Additional embodiments provide devices and methods for sequencing DNA using arrays of reaction cavities that allow for optical monitoring of solutions in the reaction cavities. Test and fill reaction schemes are disclosed that allow DNA to be sequenced. By sequencing DNA using parallel reactions contained in large arrays, DNA can be rapidly sequenced.
摘要翻译: 本发明的实施方案提供了使用包含传感器的反应腔阵列来测序DNA的装置方法,以监测包含在反应腔中的溶液的变化。 另外的实施方案提供了使用允许对反应腔中的溶液进行光学监测的反应腔阵列对DNA进行测序的装置和方法。 公开了允许DNA测序的测试和填充反应方案。 通过使用大阵列中包含的平行反应测序DNA,可以快速测序DNA。