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19 条记录 (耗时 0.072 秒)

    Methods for diagnostic imaging by regulating the administration rate of a contrast agent
    2.
    发明授权
    Methods for diagnostic imaging by regulating the administration rate of a contrast agent 失效
    通过调节造影剂的给药速率进行诊断成像的方法

    公开(公告)号：US6033645A

    公开(公告)日：2000-03-07

    申请号：US666129

    申请日：1996-06-19

    申请人： Evan C. Unger ,  Terry Matsunaga ,  Thomas A. Fritz ,  Varadarajan Ramaswami

    发明人： Evan C. Unger ,  Terry Matsunaga ,  Thomas A. Fritz ,  Varadarajan Ramaswami

    IPC分类号： A61M5/00 ,  A61B8/00 ,  A61K49/00 ,  A61K49/22 ,  A61K51/02

    CPC分类号： A61K49/223 ,  Y10S977/801 ,  Y10S977/927 ,  Y10S977/928 ,  Y10S977/929 ,  Y10S977/93

    摘要： Methods for providing an image of an internal region of a patient. Embodiments of the methods involve administering to the patient a contrast agent which comprises a vesicle composition comprising, in an aqueous carrier, a gas or gaseous precursor and vesicles comprising lipids, proteins or polymers. The patient is scanned using diagnostic imaging, such as ultrasound, to obtain a visible image of the region. The contrast agent is administered to the patient at a rate to substantially eliminate diagnostic artifacts in the image. The methods are particularly useful for diagnosing the presence of any diseased tissue in the patient.

    摘要翻译： 提供患者内部区域的图像的方法。 该方法的实施方案涉及向患者施用造影剂，其包含囊泡组合物，所述囊泡组合物在水性载体中包含气体或气体前体和包含脂质，蛋白质或聚合物的囊泡。 使用诸如超声波之类的诊断成像扫描患者，以获得该区域的可见图像。 将造影剂以基本上消除图像中的诊断伪像的速率施用于患者。 该方法对于诊断患者中任何患病组织的存在特别有用。

    Apparatus and methods for on-line monitoring of fluorinated material in headspace of vial
    9.
    发明申请
    Apparatus and methods for on-line monitoring of fluorinated material in headspace of vial 审中-公开
    在小瓶的顶空中在线监测氟化材料的装置和方法

    公开(公告)号：US20080145273A1

    公开(公告)日：2008-06-19

    申请号：US11643142

    申请日：2006-12-20

    申请人： Varadarajan Ramaswami

    发明人： Varadarajan Ramaswami

    IPC分类号： G01N35/10 ,  G01N29/02

    CPC分类号： G01N33/0049 ,  G01N29/024 ,  G01N29/0672 ,  G01N29/4418 ,  G01N2033/0081 ,  G01N2291/0222

    摘要： Apparatus and methods for monitoring the presence of an analyte in a closed vial wherein a sample contained within the closed vial is conveyed to an analyzer. The analyzer determines a value of an ultrasound velocity dependent on analyte concentration at a position within a headspace formed above the sample within the vial. An indicator is used to compare the measured value of the ultrasound velocity with a predetermined limit criteria to determine the presence or absence of the analyte. Vials wherein the presence of the analyte is denominated are indicated as product vials whereas vials wherein the absence of the analyte is denominated are indicated as rejected vials. The rejected vials are conveyed by a transferrer to a rejected vial station. A first portion of the product vials are conveyed by a sampler to a sample collection station. A second portion of the product vials are conveyed to a labeler.

    摘要翻译： 用于监测封闭小瓶中分析物的存在的装置和方法，其中封闭的小瓶中包含的样品被输送到分析器。 分析仪确定取决于在小瓶内的样品上方形成的顶部空间内的分析物浓度的超声速度的值。 使用指示器将超声速度的测量值与预定的极限标准进行比较，以确定分析物的存在或不存在。 其中分析物的存在被指定的小瓶被指示为产品小瓶，而其中不存在分析物的小瓶被指示为被拒绝的小瓶。 被拒绝的小瓶由转移器输送到拒收的小瓶站。 产品样品瓶的第一部分由取样器输送到样品收集站。 产品小瓶的第二部分被输送到标签机。

    Apparatus And Method To Prepare A Microsphere-Forming Composition
    10.
    发明申请
    Apparatus And Method To Prepare A Microsphere-Forming Composition 审中-公开
    制备微球形成组合物的装置和方法

    公开(公告)号：US20080009561A1

    公开(公告)日：2008-01-10

    申请号：US11574720

    申请日：2005-09-06

    申请人： Evan Unger ,  Varadarajan Ramaswami

    发明人： Evan Unger ,  Varadarajan Ramaswami

    IPC分类号： A61J3/07 ,  B01J13/00 ,  B01J13/02 ,  B32B5/16

    CPC分类号： A61K9/1277 ,  A61K9/0009 ,  A61K9/1075 ,  A61K9/1271 ,  B01J13/02

    摘要： A method is disclosed to prepare a microsphere-forming composition. The method provides a carbon-containing first solvent, where that first solvent is water soluble but does not comprise water The method further provides a second solvent comprising water, and (N) phosphorus-containing compounds, where (N) is greater or equal to than 1. The method forms a first mixture by mixing each of the (N) phosphorus-containing compound with the first solvent, and forms a second mixture comprising the second solvent and sodium chloride. The method then combines the first mixture and the second mixture to form the microsphere-forming composition.

    摘要翻译： 公开了一种制备微球形成组合物的方法。 该方法提供含碳的第一溶剂，其中第一溶剂是水溶性但不包含水。该方法还提供包含水和（N）含磷化合物的第二溶剂，其中（N）大于或等于 该方法通过将（N）含磷化合物与第一溶剂混合形成第一混合物，并形成包含第二溶剂和氯化钠的第二混合物。 然后该方法将第一混合物和第二混合物混合以形成形成微球体的组合物。