公开(公告)号：US20200070167A1

公开(公告)日：2020-03-05

申请号：US16557151

申请日：2019-08-30

申请人： Vortex Biosciences, Inc.

发明人： Camille Raillon ,  Elodie Sollier-Christen ,  Philippe Renaud ,  James Che

IPC分类号： B01L3/00

摘要： A system for isolating and enumerating cells or particles from a fluid are disclosed. The system includes a microfluidic chip and an impedance chip fluidly connected to the microfluidic chip. The microfluidic chip includes a substrate and a microfluidic channel disposed in the substrate between an inlet and an outlet. The microfluidic channel generates a vortex within the at least one expansion region in response to fluid flowing through the microfluidic channel.

公开(公告)号：US20190168221A1

公开(公告)日：2019-06-06

申请号：US16093468

申请日：2017-04-17

申请人： Vortex Biosciences, Inc.

发明人： Elodie Sollier ,  Michael Lee Kochersperger ,  Robert F. Englert ,  James Che ,  Kuo-Wei Huang ,  Michael Boyce-Jacino ,  Anatasia Neddersen ,  Anna Passernig ,  Bruce Richardson ,  Insang Choi

IPC分类号： B01L3/00 ,  G01N1/10 ,  G01N15/14

摘要： Microfluidic chips and cartridges and systems that include such chips are disclosed. In some embodiments, the chips include a microfluidic channel disposed in a substrate with the channel comprising at least one expansion region. The channel is configured to generate a vortex within the at least one expansion region in response to fluid through the microfluidic channel to trap cells or particles. The substrate in which the channel is formed may be relatively rigid to resist deformation.

公开(公告)号：US12128407B2

公开(公告)日：2024-10-29

申请号：US16093468

申请日：2017-04-17

申请人： Vortex Biosciences, Inc.

发明人： Elodie Sollier ,  Michael Lee Kochersperger ,  Robert F. Englert ,  James Che ,  Kuo-Wei Huang ,  Michael Boyce-Jacino ,  Anatasia Neddersen ,  Anna Passernig ,  Bruce Richardson ,  Insang Choi

IPC分类号： B01L3/00 ,  G01N1/10 ,  G01N15/10 ,  G01N15/14 ,  G01N35/10

CPC分类号： B01L3/502761 ,  B01L3/502738 ,  G01N1/10 ,  G01N15/1484 ,  B01L2200/027 ,  B01L2200/0668 ,  B01L2200/0689 ,  B01L2200/10 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2400/0403 ,  B01L2400/0487 ,  B01L2400/0633 ,  B01L2400/084 ,  G01N2015/1006 ,  G01N35/1097

摘要： Microfluidic chips and cartridges and systems that include such chips are disclosed. In some embodiments, the chips include a microfluidic channel disposed in a substrate with the channel comprising at least one expansion region. The channel is configured to generate a vortex within the at least one expansion region in response to fluid through the microfluidic channel to trap cells or particles. The substrate in which the channel is formed may be relatively rigid to resist deformation.