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    Phosphoric Acid Esters Containing Phosphorus Atoms Bridged By Polyol Units
    2.
    发明申请
    Phosphoric Acid Esters Containing Phosphorus Atoms Bridged By Polyol Units 审中-公开
    含有多元醇桥接的磷原子的磷酸酯

    公开(公告)号：US20110229427A1

    公开(公告)日：2011-09-22

    申请号：US12671792

    申请日：2008-07-29

    Applicant: Peter Klug ,  Franz-Xaver Scherl ,  Waltraud Simsch ,  Adelgunde Oberhauser

    Inventor： Peter Klug ,  Franz-Xaver Scherl ,  Waltraud Simsch ,  Adelgunde Oberhauser

    IPC: A61K8/55 ,  C07F9/09 ,  A61Q15/00 ,  A61Q19/00

    CPC classification number: A61Q19/00 ,  A61K8/86 ,  A61K8/90 ,  A61Q1/14 ,  A61Q5/02 ,  A61Q15/00 ,  A61Q17/04 ,  A61Q19/02 ,  A61Q19/04 ,  A61Q19/10 ,  C08G65/327 ,  C08G65/3353

    Abstract: The invention relates to phosphoric acid esters containing A) at least one structural unit derived from substances of constituent a), the substances of constituent a) being selected from orthophosphoric acid and at least one of the derivatives thereof; B) at least one structural unit derived from substances of constituent b), the substances of constituent b) being selected from at least one compound of formula (I) R2—O—(CH2CH2O)U(C3H6O)V(DO)w—H; and C) at least one structural unit derived from substances of constituent c), the substances of constituent c) being selected from at least one polyol which has more than 2 OH groups and can also carry at least one alkoxylate group. The alkoxylate groups are respectively formed from at least one unit selected from CH2CH2O, C3H6O and C4H8O units that can respectively be arranged in a block or in a statistically distributed manner inside the alkoxylate groups. The phosphoric acid esters contain at least two phosphorus atoms per molecule, said phosphorus atoms being bridged by a structural unit derived from the polyols having more than two OH groups or from the polyols having more than two OH groups and carrying at least one of the alkoxylate groups. The phosphoric acid esters according to the invention can be used advantageously for producing cosmetic, pharmaceutical and dermatological compositions.

    Abstract translation: 本发明涉及含有A）至少一种衍生自组分a）物质的结构单元的磷酸酯，a）选自正磷酸及其至少一种衍生物的组分物质; B）至少一种衍生自组分b）的物质的结构单元，组分物质b）选自至少一种式（I）化合物R 2 -O-（CH 2 CH 2 O）U（C 3 H 6 O）V（DO）w- H; 和C）至少一种衍生自组分c）的物质的结构单元，组分的物质c）选自至少一种具有多于2个OH基团并且还可以携带至少一个烷氧基化物的多元醇。 烷氧基化物基分别由选自可以分别以烷基化物或嵌段分布的方式排列在烷氧基化物基团内的至少一个选自CH 2 CH 2 O，C 3 H 6 O和C 4 H 8 O单元的单元形成。 磷酸酯每分子含有至少两个磷原子，所述磷原子由衍生自具有多于两个OH基团的多元醇的结构单元或多于两个OH基团的多元醇桥接，并携带至少一种烷氧基化物 团体 根据本发明的磷酸酯可有利地用于生产化妆品，药​​物和皮肤病学组合物。

    Method For Producing Alkoxylated Phosphoric Acid Triesters
    3.
    发明申请
    Method For Producing Alkoxylated Phosphoric Acid Triesters 失效
    生产烷氧基化磷酸三酯的方法

    公开(公告)号：US20110040116A1

    公开(公告)日：2011-02-17

    申请号：US12671809

    申请日：2008-07-29

    Applicant: Peter Klug ,  Franz-Xaver Scherl ,  Waltraud Simsch ,  Adelgunde Oberhauser

    Inventor： Peter Klug ,  Franz-Xaver Scherl ,  Waltraud Simsch ,  Adelgunde Oberhauser

    IPC: C07F9/09

    CPC classification number: C07F9/113 ,  A61K8/556 ,  A61K2800/48 ,  C08G65/327

    Abstract: The invention relates to a method for producing phosphoric acid triesters of formula (I). According to said method, phosphoric acid or a phosphoric acid derivative selected from orthophosphoric acid, tetraphosphoric decaoxide and polyphosphoric acid is reacted with alkoxylated alcohols of formulae (II) R1—(OA1)x-OH, (Ill) R2—(OA2)y-OH, and (IV) R3—(OA3)z-OH, in the molar ratio phosphoric acid or phosphoric acid derivative to alkoxylated alcohol of 1:2.5 to 1:3.3, at between 200 and 240° C.

    Abstract translation: 本发明涉及一种制备式（I）的磷酸三酯的方法。 根据所述方法，将磷酸或选自正磷酸，四磷酸十四烷和多磷酸的磷酸衍生物与式（II）R1-（OA1）x-OH，（III）R2-（OA2）y的烷氧基化醇反应 -OH和（IV）R3-（OA3）z-OH，其中磷酸或磷酸衍生物与烷氧基化醇的摩尔比为1:2.5至1:3.3，在200和240℃之间。

    Cosmetic or pharmaceutical compositions comprising modified polyorganosiloxanes
    6.
    发明申请
    Cosmetic or pharmaceutical compositions comprising modified polyorganosiloxanes 审中-公开
    包含改性聚有机硅氧烷的化妆品或药物组合物

    公开(公告)号：US20050255075A1

    公开(公告)日：2005-11-17

    申请号：US11082448

    申请日：2005-03-17

    Applicant: Markus Meder ,  Peter Klug ,  Torsten Henning ,  Waltraud Simsch ,  Sabine Haala ,  Carsten Mueller

    Inventor： Markus Meder ,  Peter Klug ,  Torsten Henning ,  Waltraud Simsch ,  Sabine Haala ,  Carsten Mueller

    IPC: A61K8/72 ,  A61K8/89 ,  A61K8/898 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q1/06 ,  A61Q1/10 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/04 ,  A61Q5/10 ,  A61Q15/00 ,  A61Q19/00 ,  C08G77/26 ,  C08G77/38 ,  C08L83/08 ,  A61K7/06 ,  A61K7/11

    CPC classification number: A61K8/898 ,  A61Q5/00 ,  A61Q5/004 ,  A61Q5/06 ,  A61Q5/12 ,  A61Q19/10

    Abstract: Cosmetic or pharmaceutical compositions comprising one or more substituted aminopolyorganosiloxanes (SH) with substituted amino groups which are bonded to silicon atoms of the polysiloxane basic structure via alkylene bridges or mono- or oligo(alkylenamino)alkylene bridges, where the amino groups present in the aminopolyorganosiloxanes (SH) are substituted at least partially by a radical of the formula (ε) T-CH2—CHOH—CH2—  (ε), in which T is the radical of a surfactant monoalcohol polyglycol ether with emulsifier character, the amino groups present in the aminopolyorganosiloxanes (SH) are substituted in the average ratio of at least 1.5 radicals of the formula (ε) per Si-bonded aminoalkyl group or amino-mono- or -oligo-(alkylenamino)-alkyl group, and present amino groups are, if appropriate, acylated and/or alkylated and/or benzylated and/or protonated at least partially to give amide groups, are described.

    Abstract translation: 包含一个或多个取代的氨基有机硅氧烷（S）的化妆品或药物组合物，其具有通过亚烷基桥基或单或寡（亚烷基氨基）亚烷基桥键与聚硅氧烷碱性结构的硅原子键合的取代的氨基， 其中存在于氨基多有机硅氧烷（S H H）中的氨基至少部分地被式（ε）<？in-line-formula description =“In-Line Formulas”end = “lead”？？？？>>>>（（（（（（（，，，，，，，“”“”“”“”“”“”“”“”“”“” “尾”→其中T是具有乳化剂特性的表面活性剂一元醇聚乙二醇醚的基团，存在于氨基有机硅氧烷（S）H 3中的氨基以至少1.5个基团的平均比例被取代 每个Si-键合的氨基烷基或氨基 - 单 - 或 - 二（ - 亚烷基氨基） - 烷基的式（ε），如果合适的话， 描述了至少部分酰化和/或烷基化和/或苄化和/或质子化以产生酰胺基团。

    Method for producing alkoxylated phosphoric acid triesters
    7.
    发明授权
    Method for producing alkoxylated phosphoric acid triesters 失效
    烷氧基化磷酸三酯的制备方法

    公开(公告)号：US08389756B2

    公开(公告)日：2013-03-05

    申请号：US12671809

    申请日：2008-07-29

    Applicant: Peter Klug ,  Franz-Xaver Scherl ,  Waltraud Simsch ,  Adelgunde Oberhauser

    Inventor： Peter Klug ,  Franz-Xaver Scherl ,  Waltraud Simsch ,  Adelgunde Oberhauser

    IPC: C07F9/09

    CPC classification number: C07F9/113 ,  A61K8/556 ,  A61K2800/48 ,  C08G65/327

    Abstract: The invention relates to a method for producing phosphoric acid triesters of formula (I). According to said method, phosphoric acid or a phosphoric acid derivative selected from orthophosphoric acid, tetraphosphoric decaoxide and polyphosphoric acid is reacted with alkoxylated alcohols of formulae (II) R1—(OA1)x-OH, (III) R2—(OA2)y-OH, and (IV) R3—(OA3)Z-OH, in the molar ratio phosphoric acid or phosphoric acid derivative to alkoxylated alcohol of 1:2.5 to 1:3.3, at between 200 and 240° C.

    Abstract translation: 本发明涉及一种制备式（I）的磷酸三酯的方法。 根据所述方法，将磷酸或选自正磷酸，四磷酸十四烷和多磷酸的磷酸衍生物与式（II）R1-（OA1）x-OH，（Ⅲ）R2-（OA2）y的烷氧基化醇反应 -OH和（IV）R3-（OA3）Z-OH，以磷酸或磷酸衍生物与烷氧基化醇的摩尔比为1:2.5至1:3.3，在200和240℃之间。

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