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公开(公告)号：US08436299B2
公开(公告)日：2013-05-07
申请号：US13094592
申请日：2011-04-26
IPC分类号： H01J49/40
CPC分类号： G01N27/622 , G01N27/62 , G01N27/68 , H01J49/0045 , H01J49/40
摘要： An ion mobility spectrometer has a pair of electrodes and midway along the drift chamber. A high field is applied between the electrodes and sufficient to modify ions in the region of thee electrodes such that they move at a different rate towards the collector plate. This is used to modify the time of flight of selected ions or ion clusters and enable identification of ambiguous peaks on the IMS spectrum.
摘要翻译： 离子迁移谱仪具有一对电极，沿漂移室中途。 在电极之间施加高电场并足以改变电极区域中的离子，使得它们以不同的速率朝向集电板移动。 这用于修改所选择的离子或离子簇的飞行时间，并使得能够识别IMS谱上的模糊峰。
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公开(公告)号：US08405023B2
公开(公告)日：2013-03-26
申请号：US13546823
申请日：2012-07-11
申请人： William Angus Munro
发明人： William Angus Munro
CPC分类号： H01J49/10 , G01N27/622 , H01J49/26 , H01J49/40 , H01J49/403
摘要： An ion mobility spectrometer has several electrodes spaced along its ion source region. Voltages are applied to the electrodes to produce a voltage gradient along the length of the ion source region. By varying the voltage gradient, the residence time of ions in the ion source region can be selectively varied. Typically, the spectrometer is arranged to reduce the residence time in response to a decrease in the amplitude, of an ion peak detected at the far end of the drift region.
摘要翻译： 离子迁移谱仪具有沿其离子源区域间隔开的多个电极。 电压被施加到电极以沿着离子源区域的长度产生电压梯度。 通过改变电压梯度，可以选择性地改变离子在离子源区域中的停留时间。 通常，光谱仪布置成响应于在漂移区域的远端检测到的离子峰值的幅度的减小而减少停留时间。
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公开(公告)号：US20090090196A1
公开(公告)日：2009-04-09
申请号：US12225482
申请日：2007-03-27
申请人： Alastair Clark , Henry Paul McIntyre , William Angus Munro , Stephen John Taylor , Robert Brian Turner
发明人： Alastair Clark , Henry Paul McIntyre , William Angus Munro , Stephen John Taylor , Robert Brian Turner
CPC分类号： G01N1/405 , G01N1/2214 , G01N1/40 , G01N27/62 , G01N2001/022
摘要： IMS apparatus has a preconcentrator (20) connected at the inlet (2) of an IMS detector (1) such that all gas supplied to the detector flows through the preconcentrator. The preconcentrator comprises a metal tube (21) having a layer of silicone rubber (24) exposed on its inner surface (25). An electrical resistance heating element (22) extends under the silicone rubber layer (24) and is connected to a power source (23) such that the silicone rubber layer can be periodically heated to desorb substances absorbed by the layer and release them to flow to the IMS detector 1 at a higher concentration. The silicone rubber (24) can operate in the desorption phase in the presence of air without degradation.
摘要翻译： IMS装置具有连接在IMS检测器（1）的入口（2）处的预浓缩器（20），使得供应到检测器的所有气体流过预浓缩器。 预浓缩器包括具有暴露在其内表面（25）上的硅橡胶层（24）的金属管（21）。 电阻加热元件（22）在硅橡胶层（24）的下方延伸并连接到电源（23），使得硅橡胶层能够周期性地加热以解吸该层吸收的物质并释放它们流到 IMS检测器1处于较高浓度。 硅橡胶（24）可在空气存在下在解吸阶段中运行而不降解。
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公开(公告)号：US20120273672A1
公开(公告)日：2012-11-01
申请号：US13546823
申请日：2012-07-11
申请人： William Angus Munro
发明人： William Angus Munro
IPC分类号： H01J49/26
CPC分类号： H01J49/10 , G01N27/622 , H01J49/26 , H01J49/40 , H01J49/403
摘要： An ion mobility spectrometer has several electrodes spaced along its ion source region. Voltages are applied to the electrodes to produce a voltage gradient along the length of the ion source region. By varying the voltage gradient, the residence time of ions in the ion source region can be selectively varied. Typically, the spectrometer is arranged to reduce the residence time in response to a decrease in the amplitude, of an ion peak detected at the far end of the drift region.
摘要翻译： 离子迁移谱仪具有沿其离子源区域间隔开的多个电极。 电压被施加到电极以沿着离子源区域的长度产生电压梯度。 通过改变电压梯度，可以选择性地改变离子在离子源区域中的停留时间。 通常，光谱仪布置成响应于在漂移区域的远端检测到的离子峰值的幅度的减小而减少停留时间。
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公开(公告)号：US08299428B2
公开(公告)日：2012-10-30
申请号：US12595014
申请日：2008-04-01
申请人： Alastair Clark , Stephen John Taylor , Robert Brian Turner , Richard Turner, legal representative , William Angus Munro
IPC分类号： H01J49/10
CPC分类号： H01J49/14 , H01J49/0095 , H01J49/10 , H01J49/107 , H01J49/145 , H01J49/168
摘要： A field asymmetric ion mobility spectrometer (FAIMS) has an analyte ion source assembly by which an analyte substance is ionized and supplied to the inlet of the spectrometer. The ion source assembly has an upstream source of clean, dry air and two ion sources of opposite polarity arranged at the same distance along the flow path. The ion sources are arranged so that the overall charge of the plasma produced is substantially neutral. The analyte substance is admitted via an inlet downstream of the ion sources and flows into a reaction region of enlarged cross section to slow the flow and increase the time for which the analyte molecules are exposed to the plasma.
摘要翻译： 场非对称离子迁移谱仪（FAIMS）具有分析物离子源组件，通过该分析物离子源组件将分析物质电离并提供给光谱仪的入口。 离子源组件具有清洁干燥空气的上游源和沿着流动路径相同距离排列的两个相反极性的离子源。 离子源被布置成使得所产生的等离子体的总电荷基本上是中性的。 分析物质通过离子源下游的入口进入，并流入扩大横截面的反应区域以减缓流动并增加分析物分子暴露于等离子体的时间。
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公开(公告)号：US20130056632A1
公开(公告)日：2013-03-07
申请号：US13659586
申请日：2012-10-24
CPC分类号： H01J49/14 , H01J49/0095 , H01J49/10 , H01J49/107 , H01J49/145 , H01J49/168
摘要： A field asymmetric ion mobility spectrometer (FAIMS) has an analyte ion source assembly by which an analyte substance is ionized and supplied to the inlet of the spectrometer. The ion source assembly has an upstream source of clean, dry air and two ion sources of opposite polarity arranged at the same distance along the flow path. The ion sources are arranged so that the overall charge of the plasma produced is substantially neutral. The analyte substance is admitted via an inlet downstream of the ion sources and flows into a reaction region of enlarged cross section to slow the flow and increase the time for which the analyte molecules are exposed to the plasma.
摘要翻译： 场非对称离子迁移谱仪（FAIMS）具有分析物离子源组件，通过该分析物离子源组件将分析物质电离并提供给光谱仪的入口。 离子源组件具有清洁干燥空气的上游源和沿着流动路径相同距离排列的两个相反极性的离子源。 离子源被布置成使得所产生的等离子体的总电荷基本上是中性的。 分析物质通过离子源下游的入口进入，并流入扩大横截面的反应区域以减缓流动并增加分析物分子暴露于等离子体的时间。
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公开(公告)号：US08222595B2
公开(公告)日：2012-07-17
申请号：US12444950
申请日：2007-10-22
申请人： William Angus Munro
发明人： William Angus Munro
CPC分类号： H01J49/10 , G01N27/622 , H01J49/26 , H01J49/40 , H01J49/403
摘要： An ion mobility spectrometer has several electrodes spaced along its ion source region. Voltages are applied to the electrodes to produce a voltage gradient along the length of the ion source region. By varying the voltage gradient, the residence time of ions in the ion source region can be selectively varied. Typically, the spectrometer is arranged to reduce the residence time in response to a decrease in the amplitude, of an ion peak detected at the far end of the drift region.
摘要翻译： 离子迁移谱仪具有沿其离子源区域间隔开的多个电极。 电压被施加到电极以沿着离子源区域的长度产生电压梯度。 通过改变电压梯度，可以选择性地改变离子在离子源区域中的停留时间。 通常，光谱仪布置成响应于在漂移区域的远端检测到的离子峰值的幅度的减小而减少停留时间。
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公开(公告)号：US07932489B2
公开(公告)日：2011-04-26
申请号：US11918940
申请日：2006-04-20
IPC分类号： H01J49/40
CPC分类号： G01N27/622 , G01N27/62 , G01N27/68 , H01J49/0045 , H01J49/40
摘要： An ion mobility spectrometer has a pair of electrodes (13A) and (13B) midway along the drift chamber (7). A high field is applied between the electrodes (13A) and (13B) sufficient to modify (e.g. fragment) ions in the region of the electrodes such that they move at a different rate towards the collector plate (8) . This is used to modify the time of flight of selected ions or ion clusters and enable identification of ambiguous peaks on the IMS spectrum.
摘要翻译： 离子迁移谱仪在漂移室（7）的中途具有一对电极（13A）和（13B）。 在电极（13A）和（13B）之间施加足以在电极区域中修饰（例如片段）离子的高场，使得它们以不同的速率朝向集电板（8）移动。 这用于修改所选择的离子或离子簇的飞行时间，并使得能够识别IMS谱上的模糊峰。
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公开(公告)号：US20090309019A1
公开(公告)日：2009-12-17
申请号：US12442058
申请日：2007-09-21
CPC分类号： G01N27/624
摘要： An ion mobility spectrometer has an inlet opening into an ionization region including a conventional ionization source. A series of several charged, circular electrode plates with aligned apertures extending therethrough provides a drift region on the opposite side of the ionization region from the inlet. A gas inlet connected to a source of clean, dry flushing gas opens between the ends of the drift region, with the gas flowing against the ion flow to one side to remove water molecules from the analyte. Gas flowing in the opposite direction is effective to help drive the dry analyte ions to an analysis region provided by two parallel asymmetric field plates.
摘要翻译： 离子迁移谱仪具有通向包括常规电离源的电离区域的入口。 一系列具有延伸穿过的对准孔的带电的圆形电极板提供了离入口电离区域相对侧的漂移区域。 连接到清洁干燥冲洗气体源的气体入口在漂移区的端部之间打开，气体抵抗离子流向一侧流动以从分析物中除去水分子。 沿相反方向流动的气体有助于将干燥的分析物离子驱动到由两个平行的不对称场板提供的分析区域。
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公开(公告)号：US20110284739A1
公开(公告)日：2011-11-24
申请号：US13094592
申请日：2011-04-26
CPC分类号： G01N27/622 , G01N27/62 , G01N27/68 , H01J49/0045 , H01J49/40
摘要： An ion mobility spectrometer has a pair of electrodes and midway along the drift chamber. A high field is applied between the electrodes and sufficient to modify ions in the region of thee electrodes such that they move at a different rate towards the collector plate. This is used to modify the time of flight of selected ions or ion clusters and enable identification of ambiguous peaks on the IMS spectrum.
摘要翻译： 离子迁移谱仪具有一对电极，沿漂移室中途。 在电极之间施加高电场并足以改变电极区域中的离子，使得它们以不同的速率朝向集电板移动。 这用于修改所选择的离子或离子簇的飞行时间，并使得能够识别IMS谱上的模糊峰。
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