METHODS AND COMPOSITIONS FOR RETRIEVING CELLULAR STRUCTURES BASED ON SPATIOTEMPORAL PROFILES

    公开(公告)号:US20230031708A1

    公开(公告)日:2023-02-02

    申请号:US17759357

    申请日:2021-01-25

    IPC分类号: G01N21/64 G01N15/02 G01N15/14

    摘要: Provided herein are embodiments of methods and systems for screening cellular, subcellular, and multicellular structures. In one embodiment, a method for screening is provided comprising the steps of introducing a plurality of cellular, subcellular, or multicellular structures, or a combination thereof, to an imaging system, wherein one or more structures of the plurality comprise one or more taggable markers; imaging the plurality of structures using the imaging system; identifying one or more target structures among the plurality of structures based on one or more properties of the target structures; tagging the target structures to produce tagged target structures, wherein each target structure is selectively illuminated by an excitation light, thereby causing one or more taggable markers within the target structure to be phototransformed to produce one or more phototransformed taggable markers within the target structure; and isolating one or more tagged target structures from the plurality of structures.

    A METHOD FOR EFFICIENT ELECTROCATALYTIC SYNTHESIS OF PURE LIQUID PRODUCT SOLUTIONS INCLUDING H2O2, OXYGENATES, AMMONIA, AND SO ON

    公开(公告)号:US20220259746A1

    公开(公告)日:2022-08-18

    申请号:US17597633

    申请日:2020-07-15

    摘要: A porous solid electrolyte electrosynthesis cell and corresponding related process for the direct synthesis of high purity liquid products wherein the electrosynthesis cell comprises a cathode compartment including a cathode electrode comprising a gas diffusion layer loaded with a selective reduction reaction electrocatalyst for specific reduction reactions. The electrosynthesis cell further includes an anode compartment including an anode electrode comprising a gas diffusion layer loaded with a catalyst for oxidation reactions; and a solid electrolyte compartment comprising a porous solid electrolyte; a cation exchange membrane; and an anion exchange membrane; (or two cation exchange membranes) wherein the solid electrolyte compartment is separated from the cathode and the anode by the anion exchange membrane and the cation exchange membrane (or by the two cation exchange membranes).

    TRANSCATHETER AND SERIALLY-EXPANDABLE ARTIFICIAL HEART VALVE

    公开(公告)号:US20220117731A1

    公开(公告)日:2022-04-21

    申请号:US17473653

    申请日:2021-09-13

    IPC分类号: A61F2/24

    摘要: Some embodiments are directed to a transcatheter and serially-expandable artificial heart valve, e.g., to be minimally-invasively implanted into a pediatric patient during a first procedure, and then expanded during a second procedure to accommodate for the pediatric patient's growth. Some embodiments include an expandable frame having a compressed, delivery configuration, and an expanded, deployed configuration, in which the valve is implantable within the patient. The valve can have a first working condition when the frame is expanded to a first diameter and a second working condition when the frame is expanded to a second diameter greater than the first diameter. The valve can include a plurality of leaflets configured to accommodate the expansion of the frame and growth of the patient.