利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

44 条记录 (耗时 0.034 秒)

    Systems and methods for separating constituents of biologic liquid mixtures
    1.
    发明授权
    Systems and methods for separating constituents of biologic liquid mixtures 有权
    用于分离生物液体混合物成分的系统和方法

    公开(公告)号：US08485958B2

    公开(公告)日：2013-07-16

    申请号：US13568629

    申请日：2012-08-07

    申请人： John E. Nash ,  William T. Fisher

    发明人： John E. Nash ,  William T. Fisher

    IPC分类号： B01D21/26 ,  B04B11/04

    CPC分类号： B04B1/14 ,  A61M1/3693 ,  A61M1/3696 ,  A61M1/3698 ,  B04B1/02 ,  B04B5/0407 ,  B04B5/0442 ,  B04B7/08 ,  B04B11/00 ,  B04B11/04 ,  B04B2005/0485 ,  B04B2013/006

    摘要： Centrifuges are useful to, among other things, remove red blood cells from whole blood and retain platelets and other factors in a reduced volume of plasma. Platelet rich plasma (PRP) can be obtained rapidly and is ready for immediate injection into the host. Embodiments may include valves, operated manually or automatically, to open ports that discharge the excess red blood cells and the excess plasma while retaining the platelets and other factors. High speeds used allow simple and small embodiments to be used at the patient's side during surgical procedures. The embodiments can also be used for the separation of liquids or slurries in other fields such as, for example, the separation of pigments or lubricants.

    摘要翻译： 除其他外，离心机可用于从全血中除去红细胞，并且在血浆体积减少中保留血小板和其他因子。 血小板富集血浆（PRP）可快速获得并准备立即注射入宿主。 实施例可以包括手动或自动操作的阀，以打开排出多余的红细胞和过量血浆同时保持血小板和其它因素的端口。 使用的高速度允许在外科手术期间在患者侧使用简单和小的实施例。 这些实施方案也可用于在其它领域中分离液体或浆液，例如颜料或润滑剂的分离。

    Centrifuge
    2.
    发明授权
    Centrifuge 有权

    公开(公告)号：US08469871B2

    公开(公告)日：2013-06-25

    申请号：US13209226

    申请日：2011-08-12

    申请人： John E. Nash ,  William T. Fisher

    发明人： John E. Nash ,  William T. Fisher

    IPC分类号： B04B1/14

    CPC分类号： B04B5/0442 ,  A61M1/3693 ,  A61M1/3696 ,  B01D21/245 ,  B01D21/262 ,  B01D21/34 ,  B01D2221/10 ,  B04B1/02 ,  B04B5/0407 ,  B04B7/08 ,  B04B11/04 ,  B04B2005/0485

    摘要： Centrifuges are useful to, among other things, remove red blood cells from whole blood and retain platelets and other factors in a reduced volume of plasma. Platelet rich plasma (PRP) and or platelet poor plasma (PPP) can be obtained rapidly and is ready for immediate injection into the host. Embodiments may include valves, operated manually or automatically, to open ports that discharge the excess red blood cells and the excess plasma into separate receivers while retaining the platelets and other factors in the centrifuge chamber. High speeds used allow simple and small embodiments to be used at the patient's side during surgical procedures. The embodiments can also be used for the separation of liquids or slurries in other fields such as, for example, the separation of pigments or lubricants.

    Centrifuge method and apparatus
    3.
    发明授权
    Centrifuge method and apparatus 有权
    离心机的方法和装置

    公开(公告)号：US08317672B2

    公开(公告)日：2012-11-27

    申请号：US12949781

    申请日：2010-11-19

    申请人： John E. Nash ,  William T. Fisher

    发明人： John E. Nash ,  William T. Fisher

    IPC分类号： B04B11/04

    CPC分类号： B04B1/14 ,  A61M1/3693 ,  A61M1/3696 ,  A61M1/3698 ,  B04B1/02 ,  B04B5/0407 ,  B04B5/0442 ,  B04B7/08 ,  B04B11/00 ,  B04B11/04 ,  B04B2005/0485 ,  B04B2013/006

    摘要： A single use, sterile, self-contained, compact, easy to use centrifugal separation unit provides for quick, reliable platelet concentration from whole blood. Anti-coagulated blood is injected through an elastomeric seal into a separation chamber featuring a tapered barrel and an end cap. At least one port is located in the end cap, at a desired radius from the longitudinal axis. The centrifugal field created by rotation of the chamber stratifies the blood radially, with red blood cells adjacent the wall of the barrel, and plasma found closest to the longitudinal axis. Opening the port causes the pressure of the centrifugal field to eject red blood cells or plasma, thereby increasing the concentration of platelets remaining in the chamber. After ceasing chamber rotation, the concentrated platelets are recovered.

    摘要翻译： 单次使用，无菌，独立，紧凑，易于使用的离心分离单元提供从全血中快速，可靠的血小板浓缩。 抗凝血液通过弹性体密封注射到具有锥形筒和端盖的分离室中。 至少一个端口位于端盖中，距离纵向轴线所需的半径。 通过室的旋转产生的离心场使血液径向地分层，红细胞邻近筒的壁，等离子体发现最靠近纵轴。 打开端口导致离心场的压力排出红细胞或血浆，从而增加残留在腔室中的血小板的浓度。 停止室旋转后，回收浓缩的血小板。

    CENTRIFUGE
    4.
    发明申请
    CENTRIFUGE 有权
    离心机

    公开(公告)号：US20120129674A1

    公开(公告)日：2012-05-24

    申请号：US12949781

    申请日：2010-11-19

    申请人： John E. Nash ,  William T. Fisher

    发明人： John E. Nash ,  William T. Fisher

    IPC分类号： B04B11/04 ,  B04B9/10 ,  B04B15/08

    CPC分类号： B04B1/14 ,  A61M1/3693 ,  A61M1/3696 ,  A61M1/3698 ,  B04B1/02 ,  B04B5/0407 ,  B04B5/0442 ,  B04B7/08 ,  B04B11/00 ,  B04B11/04 ,  B04B2005/0485 ,  B04B2013/006

    摘要： A single use, sterile, self-contained, compact, easy to use centrifugal separation unit provides for quick, reliable platelet concentration from whole blood. Anti-coagulated blood is injected through an elastomeric seal into a separation chamber featuring a tapered barrel and an end cap. At least one port is located in the end cap, at a desired radius from the longitudinal axis. The centrifugal field created by rotation of the chamber stratifies the blood radially, with red blood cells adjacent the wall of the barrel, and plasma found closest to the longitudinal axis. Opening the port causes the pressure of the centrifugal field to eject red blood cells or plasma, thereby increasing the concentration of platelets remaining in the chamber. After ceasing chamber rotation, the concentrated platelets are recovered.

    摘要翻译： 单次使用，无菌，独立，紧凑，易于使用的离心分离单元提供从全血中快速，可靠的血小板浓缩。 抗凝血液通过弹性体密封注射到具有锥形筒和端盖的分离室中。 至少一个端口位于端盖中，距离纵向轴线所需的半径。 通过室的旋转产生的离心场使血液径向地分层，红细胞邻近筒的壁，等离子体发现最靠近纵轴。 打开端口导致离心场的压力排出红细胞或血浆，从而增加残留在腔室中的血小板的浓度。 停止室旋转后，回收浓缩的血小板。

    Guide-wire mounted balloon modulation device and methods of use
    6.
    发明授权
    Guide-wire mounted balloon modulation device and methods of use 有权
    导丝安装球囊调制装置及使用方法

    公开(公告)号：US07771370B2

    公开(公告)日：2010-08-10

    申请号：US11439525

    申请日：2006-05-22

    申请人： Mark Eberhart ,  William T. Fisher ,  John E. Nash ,  Dennis M. Sauro

    发明人： Mark Eberhart ,  William T. Fisher ,  John E. Nash ,  Dennis M. Sauro

    IPC分类号： A61B5/00 ,  A61M29/00

    CPC分类号： A61M25/10185 ,  A61M25/0606 ,  A61M25/09041 ,  A61M25/10182 ,  A61M25/104 ,  A61M39/06 ,  A61M2210/125

    摘要： An apparatus for modulating the pressure of a fluid such as a gas within the expandable portion of a guide wire catheter. A preferred embodiment apparatus features a means for controllably gripping and releasing the open, proximal end of a tubular guide wire, means for introducing a fluid to a desired pressure and volume into the expandable portion of the tubular guide wire through the open end, and, while maintaining the pressure and volume of fluid in the tubular guide wire, a means for introducing a sealing member into the open end of said tubular guide wire to seal the fluid in the tubular guide wire. In a particularly preferred embodiment, the apparatus also features a deflation tool for piercing the seal and letting the fluid out. Using this apparatus, the tubular guide wire can be re-sealed and re-opened as necessary.

    摘要翻译： 一种用于调节诸如导丝导管的可扩张部分内的气体的流体的压力的装置。 优选的实施例装置具有用于可控制地夹紧和释放管状导丝的开口近端的装置，用于将流体引导到通过开口端的管状导丝的可膨胀部分中的期望压力和体积的装置， 同时保持管状导丝中的流体的压力和体积，用于将密封构件引入所述管状导丝的开口端以将管状导丝中的流体密封的装置。 在特别优选的实施例中，该装置还具有用于刺穿密封件并使流体流出的放气工具。 使用这种装置，可以根据需要重新密封和重新打开管状导丝。

    OFFSET CATHETER
    7.
    发明申请
    OFFSET CATHETER 有权
    偏移导管

    公开(公告)号：US20100152720A1

    公开(公告)日：2010-06-17

    申请号：US12333427

    申请日：2008-12-12

    申请人： Dennis M. Sauro ,  William T. Fisher

    发明人： Dennis M. Sauro ,  William T. Fisher

    IPC分类号： A61B18/20 ,  A61M25/09

    CPC分类号： A61B18/245 ,  A61B17/320758 ,  A61B18/24 ,  A61B2017/320775 ,  A61B2018/2238 ,  A61B2217/005 ,  A61M25/0068 ,  A61M25/007 ,  A61M25/0074 ,  A61M25/09 ,  A61M2025/09166

    摘要： Various embodiments of an offset catheter are provided. In some embodiments, an offset catheter includes a guidewire tube and a catheter coupled with an elastic and/or compressible rib. The compressible rib provides an offset or separation between the catheter and the guidewire tube in its resting state. The rib has an initial resting state, but may be forced into a compressed state. When released from the compressed state, the rib returns to its resting state. An offset catheter may be compressed and slid through a sheath. When the offset catheter emerges from the sheath, the distal tip will return to its resting state providing an operation offset.

    摘要翻译： 提供偏移导管的各种实施例。 在一些实施例中，偏移导管包括导丝管和与弹性和/或可压缩肋结合的导管。 可压缩肋在其静止状态下提供导管和导丝管之间的偏移或间隔。 肋具有初始静止状态，但可能被迫进入压缩状态。 当从压缩状态释放时，肋返回其静止状态。 偏移导管可以被压缩并滑过鞘。 当偏移导管从护套放出时，远侧末端将返回其静止状态，提供操作偏移。

    System and method of use for agent delivery and revascularizing of grafts and vessels
    9.
    发明授权
    System and method of use for agent delivery and revascularizing of grafts and vessels 失效

    公开(公告)号：US07534249B2

    公开(公告)日：2009-05-19

    申请号：US10665337

    申请日：2003-09-18

    申请人： John E. Nash ,  William T. Fisher ,  Charles W. Dodson, Jr.

    发明人： John E. Nash ,  William T. Fisher ,  Charles W. Dodson, Jr.

    IPC分类号： A61B17/22

    CPC分类号： A61B17/320758 ,  A61B17/32037 ,  A61B2017/22048 ,  A61B2017/22067 ,  A61B2217/005 ,  A61B2217/007 ,  A61M1/0058 ,  A61M1/0084 ,  A61M5/14232 ,  A61M2025/1095 ,  A61M2205/05

    摘要： A system and method for opening a lumen in an occluded blood vessel, e.g., a coronary bypass graft, of a living being. The system comprises an atherectomy catheter having a working head, e.g., a rotary impacting impeller, and a debris extraction sub-system. The atherectomy catheter is located within a guide catheter. The working head is arranged to operate on, e.g., impact, the occlusive material in the occluded vessel to open a lumen therein, whereupon some debris may be produced. The debris extraction sub-system introduces an infusate liquid at a first flow rate adjacent the working head and withdraws that liquid and some blood at a second and higher flow rate, through the guide catheter to create a differential flow adjacent the working head, whereupon the debris is withdrawn in the infusate liquid and blood for collection outside the being's body. The introduction of the infusate liquid may also be used to establish an unbalanced flow adjacent the working head to enable the atherectomy catheter to be steered hydrodynamically. A guide wire having an inflatable balloon on its distal end may be used with the atherectomy catheter to block the flow of debris distally, while enabling distal tissues to be perfused with an oxygenating liquid. At least one flow control port may be provided in the guide catheter to prevent collapse of the vessel being revascularized. A cradle is provided to fix the guide catheter and guide wire in position within the body of the being while enabling the atherectomy catheter to be advanced along the guide wire and through the guide catheter.