公开(公告)号：US20110237454A1

公开(公告)日：2011-09-29

申请号：US13034051

申请日：2011-02-24

申请人： Woong Yang Park ,  Ae Kyung Park ,  Chang Nim Im ,  Sook Ik Jeon

发明人： Woong Yang Park ,  Ae Kyung Park ,  Chang Nim Im ,  Sook Ik Jeon

IPC分类号： C40B30/04 ,  C07H21/04 ,  C07K16/00 ,  C40B40/06 ,  C40B40/10 ,  C40B40/08 ,  C12Q1/68 ,  G01N33/50 ,  G01N33/53

CPC分类号： G01N33/6893 ,  C12Q1/6883 ,  C12Q2600/158 ,  G01N2800/40 ,  Y10T436/143333

摘要： Disclosed are a composition for the diagnosis of exposure to electromagnetic radiation, comprising an agent capable of measuring the expression level of the diagnostic marker, a diagnosis kit comprising the same, a method for detecting the diagnostic marker, and a method for the diagnosis of exposure to electromagnetic radiation. The diagnostic markers are very useful for monitoring and diagnosing exposure to electromagnetic fields, and can be used as instruments by which physiological mechanisms incurred upon electromagnetic radiation exposure are examined.

公开(公告)号：US20110237453A1

公开(公告)日：2011-09-29

申请号：US13033813

申请日：2011-02-24

申请人： Woong Yang Park ,  Ae Kyung Park ,  Chang Nim Im ,  Sook Ik Jeon

发明人： Woong Yang Park ,  Ae Kyung Park ,  Chang Nim Im ,  Sook Ik Jeon

IPC分类号： C40B30/04 ,  C07H21/04 ,  C07K16/00 ,  C40B40/06 ,  C40B40/10 ,  C40B40/08 ,  C12Q1/68 ,  G01N33/50 ,  G01N33/53

CPC分类号： C12Q1/6883 ,  C12Q2600/158 ,  G01N2800/40 ,  Y10T436/143333

摘要： Disclosed are a composition for the diagnosis of exposure to electromagnetic radiation, comprising an agent capable of measuring the expression level of the diagnostic marker, a diagnosis kit comprising the same, a method for detecting the diagnostic marker, and a method for the diagnosis of exposure to electromagnetic radiation. The diagnostic markers are very useful for monitoring and diagnosing exposure to electromagnetic fields, and can be used as instruments by which physiological mechanisms incurred upon electromagnetic radiation exposure are examined.

摘要翻译： 公开了用于诊断暴露于电磁辐射的组合物，其包括能够测量诊断标记物的表达水平的试剂，包含该诊断标记物的诊断试剂盒，用于检测诊断标记物的方法和用于诊断暴露的方法 到电磁辐射。 诊断标记对于监测和诊断电磁场的暴露非常有用，可用作检查电磁辐射暴露时产生的生理机制的仪器。

公开(公告)号：US20050261265A1

公开(公告)日：2005-11-24

申请号：US10363924

申请日：2001-07-06

申请人： Sang-Chul Park ,  Woong-Yang park ,  Jeong-Soo Park ,  Kyung-A Cho ,  Deok-In Kim

发明人： Sang-Chul Park ,  Woong-Yang park ,  Jeong-Soo Park ,  Kyung-A Cho ,  Deok-In Kim

IPC分类号： G01N33/53 ,  A61K38/00 ,  A61K38/17 ,  A61K48/00 ,  A61P43/00 ,  C07K14/47 ,  C12N15/09 ,  C12Q1/02 ,  C12Q1/68 ,  G01N33/566 ,  G01N33/58 ,  G01N33/68 ,  A61K31/555

CPC分类号： G01N33/5008 ,  A61K38/1709 ,  A61K38/177 ,  C12Q1/6883 ,  C12Q2600/154 ,  C12Q2600/158 ,  G01N33/502 ,  G01N33/5044 ,  G01N33/68 ,  G01N33/6893 ,  G01N2510/00

摘要： The present invention relates to nucleic acid sequences and proteins involved in senescence and particularly, to nucleic acid sequences and proteins including amphiphysin and caveolin involved in cellular senescence and their use.

摘要翻译： 本发明涉及参与衰老的核酸序列和蛋白质，特别涉及涉及细胞衰老的核酸序列和蛋白质，包括两亲蛋白和小窝蛋白及其用途。

公开(公告)号：US5847257A

公开(公告)日：1998-12-08

申请号：US558651

申请日：1995-11-16

申请人： Jeong-Sun Seo ,  Soonhee Kim ,  Woong-Yang Park

发明人： Jeong-Sun Seo ,  Soonhee Kim ,  Woong-Yang Park

IPC分类号： A01K67/027 ,  A01K67/00 ,  C07H21/04 ,  C07K14/47 ,  C12N5/10 ,  C12N15/09 ,  C12N15/12 ,  C12N15/85 ,  C12R1/91 ,  C12N5/00 ,  C12N15/00

CPC分类号： C12N15/8509 ,  A01K67/0278 ,  C07K14/47 ,  A01K2207/15 ,  A01K2217/00 ,  A01K2217/05 ,  A01K2227/105 ,  A01K2267/0325 ,  A01K2267/0381

摘要： The present invention relates to a transgenic mouse deficient in T-cells, which is provided by fusing human heat shock protein (Hsp) gene with H2K promoter and transferring it to a mouse. Transgenic mouse line with a shrunken thymus and edficient in T-cells not having mature T-cells can be obtained.

摘要翻译： 本发明涉及通过将人热休克蛋白（Hsp）基因与H2K启动子融合并将其转移到小鼠而提供的T细胞缺陷型转基因小鼠。 可以获得在没有成熟T细胞的T细胞中具有收缩的胸腺和细胞的转基因小鼠系。

公开(公告)号：US20110237452A1

公开(公告)日：2011-09-29

申请号：US13033763

申请日：2011-02-24

申请人： Woong Yang Park ,  Ae Kyung Park ,  Chang Nim Im ,  Sook Ik Jeon

发明人： Woong Yang Park ,  Ae Kyung Park ,  Chang Nim Im ,  Sook Ik Jeon

IPC分类号： C40B30/04 ,  C07H21/04 ,  C07K16/00 ,  C40B40/08 ,  C12Q1/68 ,  G01N33/50 ,  G01N33/53

CPC分类号： C12Q1/6883 ,  C12Q2600/158 ,  G01N2800/40 ,  Y10T436/143333

摘要： Disclosed are a composition for the diagnosis of exposure to electromagnetic radiation, comprising an agent capable of measuring the expression level of the diagnostic marker, a diagnosis kit comprising the same, a method for detecting the diagnostic marker, and a method for the diagnosis of exposure to electromagnetic radiation. The diagnostic markers are very useful for monitoring and diagnosing exposure to electromagnetic fields, and can be used as instruments by which physiological mechanisms incurred upon electromagnetic radiation exposure are examined.

公开(公告)号：US07001769B2

公开(公告)日：2006-02-21

申请号：US10363924

申请日：2001-07-06

申请人： Sang-Chul Park ,  Woong-Yang Park ,  Jeong-Soo Park ,  Kyung-A Cho ,  Deok-In Kim

发明人： Sang-Chul Park ,  Woong-Yang Park ,  Jeong-Soo Park ,  Kyung-A Cho ,  Deok-In Kim

IPC分类号： C12N5/02 ,  C12P21/06

CPC分类号： G01N33/5008 ,  A61K38/1709 ,  A61K38/177 ,  C12Q1/6883 ,  C12Q2600/154 ,  C12Q2600/158 ,  G01N33/502 ,  G01N33/5044 ,  G01N33/68 ,  G01N33/6893 ,  G01N2510/00

摘要： The present invention relates to nucleic acid sequences and proteins involved in senescence and particularly, to nucleic acid sequences and proteins including amphiphysin and caveolin involved in cellular senescence and their use.

摘要翻译： 本发明涉及参与衰老的核酸序列和蛋白质，特别涉及涉及细胞衰老的核酸序列和蛋白质，包括两亲蛋白和小窝蛋白及其用途。