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1.发明申请公开(公告)号：US20110046070A1
公开(公告)日：2011-02-24
申请号：US12988163
申请日：2009-04-17
申请人： Hiroki Nagase , Xiaofei Wang
发明人： Hiroki Nagase , Xiaofei Wang
CPC分类号： C07D403/14 , A61K31/787
摘要： Disclosed are: an inhibitor of the expression of matrix metalloproteinase-9 gene; a therapeutic agent for a disease associated with matrix metalloproteinase-9; and a carcinostatic agent. Each of the agents comprises a pyrrole-imidazole polyamide having an N-methylpyrrole unit, an N-methylimidazole unit and a γ-aminobutyric acid unit. The pyrrole-imidazole polyamide can be folded at the site of the γ-aminobutyric acid unit to form a U-shaped conformation in a minor groove of a double-stranded domain comprising a part or the whole of a specific nucleotide sequence (SEQ ID NO:2, SEQ ID NO:4) included in a human matrix metalloproteinase-9 gene promoter and a strand complementary to the part or the whole of the specific nucleotide sequence. In the U-shaped conformation, a Py-Im pair, an Im/Py pair and a Py/Py pair in the pyrrole-imidazole polyamide target a C-G base pair, a G-C base pair, and both of an A-T base pair and a T-A base pair in the minor groove, respectively.
摘要翻译： 公开了：基质金属蛋白酶-9基因表达的抑制剂; 用于与基质金属蛋白酶-9相关的疾病的治疗剂; 和制癌剂。 每种试剂包括具有N-甲基吡咯单元，N-甲基咪唑单元和γ-氨基丁酸单元的吡咯 - 咪唑聚酰胺。 吡咯 - 咪唑聚酰胺可以在γ-氨基丁酸单元的位置处折叠以在双链结构域的小沟中形成U形构象，其包含部分或全部特定核苷酸序列（SEQ ID NO ：2，SEQ ID NO：4），以及与该特定核苷酸序列的一部分或全部互补的链。 在U形构象中，吡咯 - 咪唑聚酰胺靶中的Py-Im对，Im / Py对和Py / Py对为CG碱基对，GC碱基对，AT碱基对和 分别在小槽中的TA碱基对。
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2.发明申请公开(公告)号：US20050214814A1
公开(公告)日：2005-09-29
申请号：US11013546
申请日：2004-12-16
申请人： Larry Cogburn , Wilfrid Carre , Xiaofei Wang
发明人： Larry Cogburn , Wilfrid Carre , Xiaofei Wang
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6888 , C12Q2600/124 , C12Q2600/156 , C12Q2600/158 , C12Q2600/172
摘要： The present invention provides methods of screening chickens to determine those more likely to have a lean or fat phenotype. The invention also provides methods of screening chickens to identify a polymorphism associated with a fat or lean phenotype.
摘要翻译： 本发明提供筛选鸡的方法以确定更可能具有瘦或脂肪表型的那些。 本发明还提供筛选鸡以鉴定与脂肪或瘦表型相关的多态性的方法。
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公开(公告)号：US20090004214A1
公开(公告)日：2009-01-01
申请号：US12088602
申请日：2006-09-28
IPC分类号： A61K39/00 , C07K7/08 , C12N15/63 , G01N33/574 , C12N1/20
CPC分类号： A61K39/0011 , A61K39/00 , A61K45/06 , C07K14/4747
摘要： The invention concerns CD4+ T survivin epitopes and their vaccine and diagnostic uses.
摘要翻译： 本发明涉及CD4 + T存活蛋白表位及其疫苗和诊断用途。
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公开(公告)号：US20070124443A1
公开(公告)日：2007-05-31
申请号：US11549849
申请日：2006-10-16
IPC分类号： G06F15/173
CPC分类号： H04W28/12 , H04W74/06 , H04W84/18 , Y02D70/142 , Y02D70/22
摘要： Traffic streams through mesh points in a mesh network are managed. Data arriving at the mesh point are aggregated in packet queues. The packet queues segregate arriving data by the data's Quality of Service (QoS) requirement. An appropriate communication channel is selected. The communication channel is accessed through a contention access schema. An M-Request-To-Send (MRTS) message is sent to potential receiving mesh points with receiving mesh points responding with an M-Clear-to-Send (MCTS) message. Data from the packet queues is transmitted to the next mesh point. A mesh point power save mode allows battery operated mesh points to sleep preserving power.
摘要翻译： 通过网状网络中的网点进行流量管理。 到达网格点的数据被聚合在数据包队列中。 数据包队列根据数据的服务质量（QoS）要求隔离到达的数据。 选择适当的通信通道。 通信通道是通过争用访问模式访问的。 将M-Request-To-Send（MRTS）消息发送到具有以M-Clear-to-Send（MCTS）消息响应的接收网点的潜在接收网点。 来自分组队列的数据被发送到下一个网格点。 网点省电模式允许电池操作的网点保持功率睡眠。
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5.发明申请公开(公告)号：US20070092909A1
公开(公告)日：2007-04-26
申请号：US11634641
申请日：2006-12-06
申请人： Larry Cogburn , Wilfrid Carre , Xiaofei Wang
发明人： Larry Cogburn , Wilfrid Carre , Xiaofei Wang
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q2600/124 , C12Q2600/156 , C12Q2600/158
摘要： The invention provides molecular methods of screening chickens to determine those more likely to have a lean or fat phenotype by identifying the presence of at least one polymorphism in genetic material of a chicken in the thyroid hormone repressible gene (THRG) or its 3′ untranslated region (SEQ ID NO: 1) that is associated with a fat phenotype or a lean phenotype. The invention also provides methods of screening chickens to identify a polymorphism associated with a fat or lean phenotype. The invention further provides oligonucleotide probes and primers useful for detecting the polymorphisms associated with a fat or lean phenotype.
摘要翻译： 本发明提供了筛选鸡的分子方法，以通过鉴定甲状腺激素可压迫基因（THRG）或其3'非翻译区的鸡的遗传物质中存在至少一种多态性来确定更可能具有瘦或脂肪表型的鸡 （SEQ ID NO：1），其与脂肪表型或瘦表型相关联。 本发明还提供筛选鸡以鉴定与脂肪或瘦表型相关的多态性的方法。 本发明还提供了用于检测与脂肪或瘦表型相关的多态性的寡核苷酸探针和引物。
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公开(公告)号：US09521584B2
公开(公告)日：2016-12-13
申请号：US11549849
申请日：2006-10-16
CPC分类号： H04W28/12 , H04W74/06 , H04W84/18 , Y02D70/142 , Y02D70/22
摘要： Traffic streams through mesh points in a mesh network are managed. Data arriving at the mesh point are aggregated in packet queues. The packet queues segregate arriving data by the data's Quality of Service (QoS) requirement. An appropriate communication channel is selected. The communication channel is accessed through a contention access schema. An M-Request-To-Send (MRTS) message is sent to potential receiving mesh points with receiving mesh points responding with an M-Clear-to-Send (MCTS) message. Data from the packet queues is transmitted to the next mesh point. A mesh point power save mode allows battery operated mesh points to sleep preserving power.
摘要翻译： 通过网状网络中的网点进行流量管理。 到达网格点的数据被聚合在数据包队列中。 数据包队列根据数据的服务质量（QoS）要求隔离到达的数据。 选择适当的通信通道。 通信通道是通过争用访问模式访问的。 将M-Request-To-Send（MRTS）消息发送到具有以M-Clear-to-Send（MCTS）消息响应的接收网点的潜在接收网点。 来自分组队列的数据被发送到下一个网格点。 网点省电模式允许电池操作的网点保持功率睡眠。
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公开(公告)号：US08995469B2
公开(公告)日：2015-03-31
申请号：US12360531
申请日：2009-01-27
摘要： Relays can be used to facilitate communication of a packet, such as from a base station to a mobile device. The packet can include a header that designates an intended destination for the packet. The header can transfer such that the intended destination designation can be sent with or without being decompressed at a relay. If there is more than one relay involved in communication, then the header can configure such that the header is accessible without performing decompression. However, if there is one relay stop, then the header can compress the designator in such a way that decompression should occur.
摘要翻译： 可以使用继电器来促进诸如从基站到移动设备的分组的通信。 分组可以包括指定分组的预期目的地的报头。 报头可以传送，使得预期的目的地指定可以在中继站被发送还是不被解压缩。 如果通信中涉及多个中继器，则头部可以配置为使得头部可以访问而不执行解压缩。 然而，如果有一个继电器停止，则标题可以按照应该发生减压的方式压缩指示符。
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公开(公告)号：US08385193B2
公开(公告)日：2013-02-26
申请号：US11550056
申请日：2006-10-17
IPC分类号： H04J1/16
CPC分类号： H04L47/15 , H04L47/10 , H04L47/125 , H04L47/70 , H04L47/724 , H04L47/822 , H04L47/824 , H04W28/12 , H04W72/0486 , H04W84/18
摘要： An apparatus and method of controlling a traffic stream in a mesh network comprising receiving at a second node a traffic stream admission request to admit a traffic stream from a first node, determining a traffic load for the second node, and determining whether to admit or deny the traffic stream from the first node using the traffic load.
摘要翻译： 一种控制网状网络中的业务流的装置和方法，包括在第二节点处接收业务流准入请求以允许来自第一节点的业务流，确定所述第二节点的业务负载，以及确定是否允许或拒绝 来自第一个节点的流量流使用流量负载。
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公开(公告)号：US20090238185A1
公开(公告)日：2009-09-24
申请号：US12360531
申请日：2009-01-27
摘要： Relays can be used to facilitate communication of a packet, such as from a base station to a mobile device. The packet can include a header that designates an intended destination for the packet. The header can transfer such that the intended destination designation can be sent with or without being decompressed at a relay. If there is more than one relay involved in communication, then the header can configure such that the header is accessible without performing decompression. However, if there is one relay stop, then the header can compress the designator in such a way that decompression should occur.
摘要翻译： 可以使用继电器来促进诸如从基站到移动设备的分组的通信。 分组可以包括指定分组的预期目的地的报头。 报头可以传送，使得预期的目的地指定可以在中继站被发送还是不被解压缩。 如果通信中涉及多个中继器，则头部可以配置为使得头部可以访问而不执行解压缩。 然而，如果有一个继电器停止，则标题可以按照应该发生减压的方式压缩指示符。
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10.发明授权公开(公告)号：US09369918B2
公开(公告)日：2016-06-14
申请号：US13529651
申请日：2012-06-21
CPC分类号： H04W74/04 , H04W28/06 , H04W28/26 , H04W74/004 , H04W74/006 , H04W74/06 , H04W74/0808 , H04W74/0816 , H04W76/11 , H04W88/08
摘要： Enhanced protocols and devices may be used to alleviate loss of spectrum efficiency in wideband transmission. The protocols may implement a wideband transmission opportunity (TXOP) truncation where one or more of the channels involved in communication over the wideband are released. In one scenario, a wireless transmit/receive unit (WTRU) may obtain a TXOP for a 2 MHz bandwidth mode frame transmission with another device capable of operating in a 2 MHz bandwidth mode and a 1 MHz bandwidth mode. The WTRU may conduct a request-to-send (RTS)/clear-to-send (CTS) frame exchange in the second bandwidth mode, and truncate the TXOP by transmitting a contention free (CF)-End frame in the first and second bandwidth modes. In another scenario, an AP may obtain a TXOP for a 2 MHz bandwidth mode frame transmission with a WTRU capable of both 2 MHz and 1 MHz bandwidth modes.
摘要翻译： 可以使用增强的协议和设备来减轻宽带传输中频谱效率的损失。 协议可以实现宽带传输机会（TXOP）截断，其中涉及通过宽带通信的一个或多个信道被释放。 在一种情况下，无线发射/接收单元（WTRU）可以与能够以2MHz带宽模式和1MHz带宽模式操作的另一设备获得用于2MHz带宽模式帧传输的TXOP。 WTRU可以在第二带宽模式中进行请求发送（RTS）/清除发送（CTS）帧交换，并且通过在第一和第二帧中发送无竞争（CF）-End帧来截断TXOP 带宽模式。 在另一种情况下，AP可以获得具有能够兼容2MHz和1MHz带宽模式的WTRU的2MHz带宽模式帧传输的TXOP。
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