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    Paliperidone double-layered osmotic pump controlled release tablet and preparation method thereof
    2.
    发明授权
    Paliperidone double-layered osmotic pump controlled release tablet and preparation method thereof 有权
    哌啶酮双层渗透泵控释片及其制备方法

    公开(公告)号：US08920835B2

    公开(公告)日：2014-12-30

    申请号：US13512402

    申请日：2010-11-22

    Applicant: Yong Gan ,  Chunliu Zhu ,  Qingmin Yang ,  Jingyi Wang ,  Xiaoqing Zheng ,  Li Gan ,  Xinxin Zhang

    Inventor： Yong Gan ,  Chunliu Zhu ,  Qingmin Yang ,  Jingyi Wang ,  Xiaoqing Zheng ,  Li Gan ,  Xinxin Zhang

    IPC: A61K9/24 ,  A61K9/28 ,  A61K31/519 ,  A61P25/18 ,  B05D5/00 ,  A61K9/00 ,  A61K9/20 ,  A61K31/517

    CPC classification number: A61K9/0004 ,  A61K9/2086 ,  A61K9/2866 ,  A61K31/517

    Abstract: A paliperidone double-layered osmotic pump controlled release tablet and the preparation method thereof are disclosed. The double-layered osmotic pump controlled release tablet comprises a rigid membrane, a push layer, a drug layer, an isolation layer and an aesthetic coating, wherein the rigid membrane contains a semi-permeable polymer, a porogen and/or a plasticizer and has one or more drug release orifices on one end, the push layer comprises an expanding material, an osmotic agent, a binder, a colorant and a lubricant, the drug layer contains a pharmaceutically active ingredient, a hydrophilic polymer, an osmotic agent, a colorant, a lubricant and an antistatic agent, the isolation layer is located between the inner surface of the rigid membrane and the push layer, and contains a hydrophilic polymer. The paliperidone double-layered osmotic pump controlled release tablet shows an increasing drug release rate at early stage and keeps a constant drug release rate at later stage.

    Abstract translation: 披露了一种帕培酮双层渗透泵控释片及其制备方法。 双层渗透泵控制释放片剂包括刚性膜，推层，药物层，隔离层和美容涂层，其中刚性膜含有半透性聚合物，致孔剂和/或增塑剂，并且具有 一个或多个药物释放孔在一端，推层包括膨胀材料，渗透剂，粘合剂，着色剂和润滑剂，药物层含有药物活性成分，亲水性聚合物，渗透剂，着色剂 ，润滑剂和抗静电剂，隔离层位于刚性膜的内表面和推层之间，并含有亲水性聚合物。 帕潘立酮双层渗透泵控释片剂在早期阶段呈现出药物释放速率的增加，药物释放速率在后期保持不变。

    HYBRID POWER DRIVE SYSTEM AND A DRIVE METHOD OF THE SAME
    7.
    发明申请
    HYBRID POWER DRIVE SYSTEM AND A DRIVE METHOD OF THE SAME 审中-公开
    混合动力驱动系统及其驱动方法

    公开(公告)号：US20120004073A1

    公开(公告)日：2012-01-05

    申请号：US13162665

    申请日：2011-06-17

    Applicant: Xiaohua TANG ,  Xinxin Zhang ,  Fei Luo ,  Zhigao Xiao

    Inventor： Xiaohua TANG ,  Xinxin Zhang ,  Fei Luo ,  Zhigao Xiao

    IPC: B60W10/02 ,  B60W20/00 ,  F16H35/00

    CPC classification number: B60K6/448 ,  B60K6/442 ,  B60K6/52 ,  B60K6/547 ,  B60W10/06 ,  B60W10/08 ,  B60W10/113 ,  B60W20/11 ,  B60W30/18127 ,  B60Y2400/428 ,  Y02T10/6234 ,  Y02T10/6243 ,  Y02T10/6265 ,  Y02T10/6286 ,  Y10T74/19 ,  Y10T477/26

    Abstract: A hybrid power drive system comprises: an engine operatively coupled to a gearbox; a first motor operatively coupled to the engine; a first wheel group operatively coupled to the gearbox; a second motor operatively coupled to a second wheel group; an energy storage device connected to the first motor and the second motor, respectively. The gearbox comprises a first decelerating mechanism and a second decelerating mechanism. The first wheel group is operatively coupled to the first decelerating mechanism and the second decelerating mechanism, respectively. The engine is operatively coupled to the first decelerating mechanism and the second decelerating mechanism, respectively.

    Abstract translation: 混合动力驱动系统包括：可操作地联接到齿轮箱的发动机; 可操作地联接到发动机的第一马达; 操作地联接到所述变速箱的第一轮组; 可操作地联接到第二轮组的第二马达; 分别连接到第一电动机和第二电动机的能量存储装置。 变速箱包括第一减速机构和第二减速机构。 第一轮组分别可操作地联接到第一减速机构和第二减速机构。 发动机分别可操作地联接到第一减速机构和第二减速机构。

    Doll's head
    10.
    外观设计
    Doll's head 有权

    公开(公告)号：USD1006913S1

    公开(公告)日：2023-12-05

    申请号：US29880781

    申请日：2023-07-27

    Applicant: Xinxin Zhang

    Designer： Xinxin Zhang

    Abstract: FIG. 1 is a front elevational view of a doll's head, showing my new design;
    FIG. 2 is a rear elevational view thereof;
    FIG. 3 is a left side view thereof;
    FIG. 4 is a right side view thereof;
    FIG. 5 is a top plan view thereof;
    FIG. 6 is a bottom plan view thereof; and,
    FIG. 7 is a left perspective view thereof.

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