BIODEGRADABLE COPOLYMER AND THERMOSENSITIVE MATERIAL
    4.
    发明申请
    BIODEGRADABLE COPOLYMER AND THERMOSENSITIVE MATERIAL 有权
    可生物降解的共聚物和耐热材料

    公开(公告)号:US20110065829A1

    公开(公告)日:2011-03-17

    申请号:US12952724

    申请日:2010-11-23

    Abstract: The disclosed is a biodegradable copolymer, an amphiphilic diblock copolymer, composed of a hydrophilic segment and a hydrophobic segment. The hydrophilic segment is an endcapped PEG or derivatives thereof. The hydrophilic segment is a random polymer polymerized of lactone or cyclic C3-C6 molecule and lactic acid/glycolic acid. There is no coupling agent between the hydrophilic and hydrophobic segments, and the biodegradable copolymer is formed by one-pot ring-opening polymerization. The biodegradable copolymer can be dissolved in water to form a thermosensitive material having a phase transfer temperature of 25 to 50° C., thereby being applied to biological activity factor delivery, tissue engineering, cell culture and biological glue.

    Abstract translation: 所公开的是由亲水链段和疏水链段组成的可生物降解的共聚物,两亲二嵌段共聚物。 亲水片段是封端的PEG或其衍生物。 亲水段是内酯或环状C 3 -C 6分子和乳酸/乙醇酸聚合的无规聚合物。 亲水和疏水链段之间没有偶联剂,生物降解共聚物是通过一锅开环聚合形成的。 可生物降解的共聚物可以溶解在水中以形成相转移温度为25-50℃的热敏材料,从而适用于生物活性因子递送,组织工程,细胞培养和生物胶。

    Ceramic reinforcement material
    8.
    发明申请
    Ceramic reinforcement material 审中-公开
    陶瓷增强材料

    公开(公告)号:US20070237939A1

    公开(公告)日:2007-10-11

    申请号:US11394759

    申请日:2006-03-31

    CPC classification number: C04B35/447 C03C27/06 C04B2235/96 Y10T428/249924

    Abstract: The present invention provides a ceramic reinforcement material with a weak interface. The reinforcement material of the present invention contains several ceramic layers, wherein those ceramic layers can be a ceramic layer, a metal layer or a polymer layer. The present invention utilizes the bonding weakness of a middle layer or in between a middle layer and the ceramic layer to create a weak interface in the ceramic reinforcement material. The reinforcement with the weak interface can be added into other materials to improve their toughness.

    Abstract translation: 本发明提供一种具有弱界面的陶瓷增强材料。 本发明的增强材料包含几个陶瓷层,其中这些陶瓷层可以是陶瓷层,金属层或聚合物层。 本发明利用中间层或中间层与陶瓷层之间的结合弱点在陶瓷增强材料中产生弱界面。 具有弱界面的钢筋可以添加到其他材料中以提高其韧性。

    Biodegradable copolymer and thermosensitive material
    9.
    发明授权
    Biodegradable copolymer and thermosensitive material 有权
    可生物降解的共聚物和热敏材料

    公开(公告)号:US08309623B2

    公开(公告)日:2012-11-13

    申请号:US12952724

    申请日:2010-11-23

    Abstract: The disclosed is a biodegradable copolymer, an amphiphilic diblock copolymer, composed of a hydrophilic segment and a hydrophobic segment. The hydrophilic segment is an endcapped PEG or derivatives thereof. The hydrophilic segment is a random polymer polymerized of lactone or cyclic C3-C6 molecule and lactic acid/glycolic acid. There is no coupling agent between the hydrophilic and hydrophobic segments, and the biodegradable copolymer is formed by one-pot ring-opening polymerization. The biodegradable copolymer can be dissolved in water to form a thermosensitive material having a phase transfer temperature of 25 to 50° C., thereby being applied to biological activity factor delivery, tissue engineering, cell culture and biological glue.

    Abstract translation: 所公开的是由亲水链段和疏水链段组成的可生物降解的共聚物,两亲二嵌段共聚物。 亲水片段是封端的PEG或其衍生物。 亲水段是内酯或环状C 3 -C 6分子和乳酸/乙醇酸聚合的无规聚合物。 亲水和疏水链段之间没有偶联剂,生物降解共聚物是通过一锅开环聚合形成的。 可生物降解的共聚物可以溶解在水中以形成相转移温度为25-50℃的热敏材料,从而适用于生物活性因子递送,组织工程,细胞培养和生物胶。

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