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公开(公告)号：US09434775B2
公开(公告)日：2016-09-06
申请号：US12384165
申请日：2009-04-01
申请人： Hiroyuki Aburatani , Yoshitaka Hippo , Hirokazu Taniguchi , Yong xin Chen , Shumpei Ishikawa , Shin-ichi Fukumoto , Takahiro Shimamura , Naoka Kamimura , Ying qiu Guo , Shogo Yamamoto , Yukio Ito , Hirotaka Ito , Toshihiko Ohtomo
发明人： Hiroyuki Aburatani , Yoshitaka Hippo , Hirokazu Taniguchi , Yong xin Chen , Shumpei Ishikawa , Shin-ichi Fukumoto , Takahiro Shimamura , Naoka Kamimura , Ying qiu Guo , Shogo Yamamoto , Yukio Ito , Hirotaka Ito , Toshihiko Ohtomo
CPC分类号： C07K14/47 , C12Q1/6886 , C12Q2600/136
摘要： Disclosed are a protein encoded by a gene having a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a fragment thereof, an antibody recognizing the protein or antigen-binding fragment thereof, and a polynucleotide having a sequence comprising at least 12 consecutive nucleotides of a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a nucleotide sequence complementary thereto. The gene and the protein of the invention is useful for diagnosing and treating cancer.
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公开(公告)号：US09376475B2
公开(公告)日：2016-06-28
申请号：US12807314
申请日：2010-08-31
申请人： Hiroyuki Aburatani , Yoshitaka Hippo , Hirokazu Taniguchi , Yong xin Chen , Shumpei Ishikawa , Shin-ichi Fukumoto , Takahiro Shimamura , Naoko Kamimura , Ying qiu Guo , Shogo Yamamoto , Yukio Ito , Hirotaka Ito , Toshihiko Ohtomo
发明人： Hiroyuki Aburatani , Yoshitaka Hippo , Hirokazu Taniguchi , Yong xin Chen , Shumpei Ishikawa , Shin-ichi Fukumoto , Takahiro Shimamura , Naoko Kamimura , Ying qiu Guo , Shogo Yamamoto , Yukio Ito , Hirotaka Ito , Toshihiko Ohtomo
CPC分类号： C07K14/47 , C12Q1/6886 , C12Q2600/136
摘要： Disclosed are a protein encoded by a gene having a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a fragment thereof, an antibody recognizing the protein or antigen-binding fragment thereof, and a polynucleotide having a sequence comprising at least 12 consecutive nucleotides of a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a nucleotide sequence complementary thereto. The gene and the protein of the invention is useful for diagnosing and treating cancer.
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公开(公告)号：US20110023267A1
公开(公告)日：2011-02-03
申请号：US12864159
申请日：2009-09-22
申请人： Ying Qiu , Liming Fang , Jinyuan Xu , Jie Ma
发明人： Ying Qiu , Liming Fang , Jinyuan Xu , Jie Ma
IPC分类号： B60B33/00
CPC分类号： B60B33/021 , B60B33/0007 , B60B33/0021 , B60B33/0028 , B60B33/0039 , B60B33/0049 , B60B33/0057 , B60B33/0068 , B60B33/0073 , B60B33/0092 , B62B5/0423 , B62B5/0452 , Y10T16/1847
摘要： The invention relates a lockable caster wheel. The lockable caster wheel can be widely used in shopping carts, luggage carts, strollers, turnover carts, stretcher cars and many other trolleys. The controlling mechanism of the lockable caster wheel comprises a controller which comprises a signal receiving device and a locking device which is controlled by the controller. The locking mechanism further comprises a revolving damper which comprises a shell having a restricting structure and a damping wheel located inside the shell. The shell, through its restricting structure, separates from or connects with the locking device to form unlocked or locked states. The damping wheel connects with the wheel components. The caster wheel uses a damper. Beyond the allowed area of use, the trolleys can be slowly pushed for a few of meters because of the damper effect, but it will not suddenly stop completely. Therefore it will not present danger to the users. It can also prevent the casters from being damaged by a forceful push when they are locked.
摘要翻译： 本发明涉及可锁定脚轮。 可锁定脚轮可广泛用于购物车，行李车，婴儿推车，周转车，担架车和许多其他手推车。 可锁定脚轮的控制机构包括控制器，该控制器包括由控制器控制的信号接收装置和锁定装置。 锁定机构还包括一个旋转阻尼器，它包括具有限制结构的壳体和位于壳体内部的阻尼轮。 壳体通过其限制结构与锁定装置分离或连接以形成解锁或锁定状态。 阻尼轮与车轮部件连接。 脚轮使用阻尼器。 超过允许的使用范围，手推车可以缓慢推动几米，因为阻尼效应，但不会完全停止。 所以不会给用户带来危险。 它也可以防止脚轮在锁定时被强力推动而损坏。
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公开(公告)号：US07812128B2
公开(公告)日：2010-10-12
申请号：US12229750
申请日：2008-08-26
申请人： Hiroyuki Aburatani , Yoshitaka Hippo , Hirokazu Taniguchi , Yong xin Chen , Shumpei Ishikawa , Shin-ichi Fukumoto , Takahiro Shimamura , Naoko Kamimura , Ying qiu Guo , Shogo Yamamoto , Yukio Ito , Hirotaka Ito , Toshihiko Ohtomo
发明人： Hiroyuki Aburatani , Yoshitaka Hippo , Hirokazu Taniguchi , Yong xin Chen , Shumpei Ishikawa , Shin-ichi Fukumoto , Takahiro Shimamura , Naoko Kamimura , Ying qiu Guo , Shogo Yamamoto , Yukio Ito , Hirotaka Ito , Toshihiko Ohtomo
IPC分类号： C07K14/00
CPC分类号： C07K14/47 , C12Q1/6886 , C12Q2600/136
摘要： Disclosed are a protein encoded by a gene having a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a fragment thereof, an antibody recognizing the protein or antigen-binding fragment thereof, and a polynucleotide having a sequence comprising at least 12 consecutive nucleotides of a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a nucleotide sequence complementary thereto. The gene and the protein of the invention is useful for diagnosing and treating cancer.
摘要翻译： 公开了由具有由SEQ ID NO：1至65中任一个表示的核苷酸序列或其片段的基因编码的蛋白质，识别该蛋白质或其抗原结合片段的抗体，以及具有至少12个 由SEQ ID NO：1至65中任一个表示的核苷酸序列的连续核苷酸或与其互补的核苷酸序列。 本发明的基因和蛋白质可用于诊断和治疗癌症。
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公开(公告)号：US20080153104A1
公开(公告)日：2008-06-26
申请号：US10568471
申请日：2004-08-06
申请人： Hiroyuki Aburatani , Yoshitaka Hippo , Hirokazu Taniguchi , Yong xin Chen , Shumpei Ishikawa , Shin-ichi Fukumoto , Takahiro Shimamura , Naoko Kamimura , Ying qiu Guo , Shogo Yamamoto , Yukio Ito , Hirotaka Ito , Toshihiko Ohtomo
发明人： Hiroyuki Aburatani , Yoshitaka Hippo , Hirokazu Taniguchi , Yong xin Chen , Shumpei Ishikawa , Shin-ichi Fukumoto , Takahiro Shimamura , Naoko Kamimura , Ying qiu Guo , Shogo Yamamoto , Yukio Ito , Hirotaka Ito , Toshihiko Ohtomo
IPC分类号： G01N33/53 , G01N33/48 , G01N33/566 , C12Q1/02
CPC分类号： C12Q1/6886 , A61K31/711 , A61K38/00 , A61K39/0011 , C07K14/82 , C07K16/30 , C12Q2600/136 , G01N33/57484
摘要： Disclosed are a protein encoded by a gene having a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a fragment thereof, an antibody recognizing the protein or antigen-binding fragment thereof, and a polynucleotide having a sequence comprising at least 12 consecutive nucleotides of a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a nucleotide sequence complementary thereto. The gene and the protein of the invention is useful for diagnosing and treating cancer.
摘要翻译： 公开了由具有由SEQ ID NO：1至65中任一个表示的核苷酸序列或其片段的基因编码的蛋白质，识别该蛋白质或其抗原结合片段的抗体，以及具有至少12个 由SEQ ID NO：1至65中任一个表示的核苷酸序列的连续核苷酸或与其互补的核苷酸序列。 本发明的基因和蛋白质可用于诊断和治疗癌症。
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公开(公告)号：US20130050795A1
公开(公告)日：2013-02-28
申请号：US13340410
申请日：2011-12-29
申请人： Ying QIU , Zhixue HE , Ming LUO , Xiaoyin ZHANG , Qi YANG
发明人： Ying QIU , Zhixue HE , Ming LUO , Xiaoyin ZHANG , Qi YANG
CPC分类号： G02F1/3536 , G02F1/3532 , G02F2203/58
摘要： A system and method for generating an optical comb are provided. The system comprises at least one modulator for modulating a continuous wave sequentially by using at least one signal, respectively so as to generate a comb wave having a first plurality of subcarriers; and a nonlinear medium for causing the respective subcarriers of the comb wave to perform four-wave mixing to thereby generate a comb wave having a second plurality of subcarriers as the optical comb. With the present system and method, an ultra-wide spectrum optical comb with stable frequencies may be generated.
摘要翻译： 提供了一种用于产生光梳的系统和方法。 该系统包括至少一个调制器，用于分别通过使用至少一个信号来顺序地调制连续波，以产生具有第一多个子载波的梳状波; 以及用于使梳状波的各个子载波进行四波混频从而产生具有第二多个子载波的梳状波作为光梳的非线性介质。 利用本系统和方法，可以产生具有稳定频率的超宽谱光梳。
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公开(公告)号：US20090226918A1
公开(公告)日：2009-09-10
申请号：US12384165
申请日：2009-04-01
申请人： Hiroyuki Aburatani , Yoshitaka Hippo , Hirokazu Taniguchi , Yong xin Chen , Shumpei Ishikawa , Shin-ichi Fukumoto , Takahiro Shimamura , Naoka Kamimura , Ying qiu Guo , Shogo Yamamoto , Yukio Ito , Hirotaka Ito , Toshihiko Ohtomo
发明人： Hiroyuki Aburatani , Yoshitaka Hippo , Hirokazu Taniguchi , Yong xin Chen , Shumpei Ishikawa , Shin-ichi Fukumoto , Takahiro Shimamura , Naoka Kamimura , Ying qiu Guo , Shogo Yamamoto , Yukio Ito , Hirotaka Ito , Toshihiko Ohtomo
CPC分类号： C07K14/47 , C12Q1/6886 , C12Q2600/136
摘要： Disclosed are a protein encoded by a gene having a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a fragment thereof, an antibody recognizing the protein or antigen-binding fragment thereof, and a polynucleotide having a sequence comprising at least 12 consecutive nucleotides of a nucleotide sequence represented by any of SEQ ID NOs: 1 to 65 or a nucleotide sequence complementary thereto. The gene and the protein of the invention is useful for diagnosing and treating cancer.
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公开(公告)号：US08924519B2
公开(公告)日：2014-12-30
申请号：US12611255
申请日：2009-11-03
申请人： Leszek Mazur , Ying Qiu , Sean D. Daniel
发明人： Leszek Mazur , Ying Qiu , Sean D. Daniel
IPC分类号： G06F15/177 , H04L12/24 , H04L12/26 , H04L29/12 , H04L29/08
CPC分类号： H04L41/12 , H04L29/12066 , H04L29/12226 , H04L43/0811 , H04L61/1511 , H04L61/2015 , H04L67/1002 , H04L67/1036
摘要： A client process may identify a local DNS server and may change a DHCP-supplied DNS setting to the local DNS server when the local DNS server is present. The client process may periodically monitor the local DNS server and, if the local DNS server is not present, the client process may revert the DNS setting to the originally supplied DHCP DNS setting. The client process may actively monitor the local DNS server by initiating communication with the local DNS server, or may passively monitor by listening for activity by the local DNS server.
摘要翻译： 客户端进程可能会识别本地DNS服务器，并且可能会在本地DNS服务器存在时将DHCP提供的DNS设置更改为本地DNS服务器。 客户端进程可以定期监视本地DNS服务器，如果本地DNS服务器不存在，则客户端进程可以将DNS设置恢复为原始提供的DHCP DNS设置。 客户端进程可以通过发起与本地DNS服务器的通信来主动监视本地DNS服务器，或者可以通过监听本地DNS服务器的活动来进行被动监视。
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公开(公告)号：US08724204B2
公开(公告)日：2014-05-13
申请号：US13340410
申请日：2011-12-29
申请人： Ying Qiu , Zhixue He , Ming Luo , Xiaoyin Zhang , Qi Yang
发明人： Ying Qiu , Zhixue He , Ming Luo , Xiaoyin Zhang , Qi Yang
CPC分类号： G02F1/3536 , G02F1/3532 , G02F2203/58
摘要： A system and method for generating an optical comb are provided. The system comprises at least one modulator for modulating a continuous wave sequentially by using at least one signal, respectively so as to generate a comb wave having a first plurality of subcarriers; and a nonlinear medium for causing the respective subcarriers of the comb wave to perform four-wave mixing to thereby generate a comb wave having a second plurality of subcarriers as the optical comb. With the present system and method, an ultra-wide spectrum optical comb with stable frequencies may be generated.
摘要翻译： 提供了一种用于产生光梳的系统和方法。 该系统包括至少一个调制器，用于分别通过使用至少一个信号来顺序地调制连续波，以产生具有第一多个子载波的梳状波; 以及用于使梳状波的各个子载波进行四波混频从而产生具有第二多个子载波的梳状波作为光梳的非线性介质。 利用本系统和方法，可以产生具有稳定频率的超宽谱光梳。
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公开(公告)号：US08464843B2
公开(公告)日：2013-06-18
申请号：US12864159
申请日：2009-09-22
申请人： Ying Qiu , Liming Fang , Jinyuan Xu , Jie Ma
发明人： Ying Qiu , Liming Fang , Jinyuan Xu , Jie Ma
IPC分类号： B60B33/00
CPC分类号： B60B33/021 , B60B33/0007 , B60B33/0021 , B60B33/0028 , B60B33/0039 , B60B33/0049 , B60B33/0057 , B60B33/0068 , B60B33/0073 , B60B33/0092 , B62B5/0423 , B62B5/0452 , Y10T16/1847
摘要： The invention relates a lockable caster wheel. The lockable caster wheel can be widely used in shopping carts, luggage carts, strollers, turnover carts, stretcher cars and many other trolleys. The controlling mechanism of the lockable caster wheel comprises a controller which comprises a signal receiving device and a locking device which is controlled by the controller. The locking mechanism further comprises a revolving damper which comprises a shell having a restricting structure and a damping wheel located inside the shell. The shell, through its restricting structure, separates from or connects with the locking device to form unlocked or locked states. The damping wheel connects with the wheel assembly. The caster wheel uses a damper. Beyond the allowed area of use, the trolleys can be slowly pushed for a few of meters because of the damper effect, but it will not suddenly stop completely. Therefore it will not present danger to the users. It can also prevent the casters from being damaged by a forceful push when they are locked.
摘要翻译： 本发明涉及可锁定脚轮。 可锁定脚轮可广泛用于购物车，行李车，婴儿推车，周转车，担架车和许多其他手推车。 可锁定脚轮的控制机构包括控制器，该控制器包括由控制器控制的信号接收装置和锁定装置。 锁定机构还包括一个旋转阻尼器，它包括具有限制结构的壳体和位于壳体内部的阻尼轮。 壳体通过其限制结构与锁定装置分离或连接以形成解锁或锁定状态。 阻尼轮与车轮组件连接。 脚轮使用阻尼器。 超过允许的使用范围，手推车可以缓慢推动几米，因为阻尼效应，但不会完全停止。 所以不会给用户带来危险。 它也可以防止脚轮在锁定时被强力推动而损坏。
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