公开(公告)号：US08657762B2

公开(公告)日：2014-02-25

申请号：US12669254

申请日：2008-07-18

申请人： Tetsuya Takashima ,  Masaki Fujiwara ,  Takeshi Nishida ,  Yoshinori Amano ,  Toshiki Matsumoto ,  Kenichi Hamanaka ,  Keisuke Matsumura ,  Yohei Hashimoto

发明人： Tetsuya Takashima ,  Masaki Fujiwara ,  Takeshi Nishida ,  Yoshinori Amano ,  Toshiki Matsumoto ,  Kenichi Hamanaka ,  Keisuke Matsumura ,  Yohei Hashimoto

IPC分类号： A61B5/00

CPC分类号： A61B5/150954 ,  A61B5/150022 ,  A61B5/150099 ,  A61B5/150267 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/150793 ,  A61B5/150847 ,  A61B5/15087 ,  A61B5/150961 ,  A61B5/15113 ,  A61B5/15136 ,  A61B5/15146 ,  A61B5/1519 ,  A61B5/157

摘要： A blood test device (21) ensuring successful measurement wherein fingers scarcely slip out from the blood test device and blood never sticks to other sites in the course from the puncture of the patient's skin to the completion of the blood test. This blood test device (21) comprises a cartridge (24) in which sensors (23) pooling blood oozing out from the punctured skin are stored in a layered state, a transport unit transporting a single sensor sheet (23) from the inside of the cartridge (24) to the outside, a holder (25) holding the transported sensor (23), a laser emitting unit (26) puncturing the skin in the state where the sensor (23) is held by the holder (25), and a pump (28) keeping the inside of the holder (25) and the inside of the cartridge (24) under negative pressure.

摘要翻译： 一种确保成功测量的血液检查装置（21），其中手指几乎不从血液检查装置中滑出，并且在从穿刺患者皮肤到完成血液测试的过程中，血液不会粘附到其他部位。 该血液检查装置（21）包括：盒（24），其中收集从穿刺皮肤渗出的血液的传感器（23）以分层状态存储;传送单元，其从内部传送单个传感器片（23） 盒（24）到外部，保持传送传感器（23）的保持器（25），在传感器（23）被保持器（25）保持的状态下刺穿皮肤的激光发射单元（26） 将保持器（25）的内部和药筒（24）的内部保持在负压下的泵（28）。

公开(公告)号：US20130108510A1

公开(公告)日：2013-05-02

申请号：US13807388

申请日：2011-09-07

申请人： Yoshiki Takeuchi ,  Toshiki Matsumoto ,  Eiji Okuda ,  Kiyohiro Horikawa ,  Takahiro Watanabe ,  Kaoru Shigematsu ,  Yoshinori Amano ,  Shinichi Kojima

发明人： Yoshiki Takeuchi ,  Toshiki Matsumoto ,  Eiji Okuda ,  Kiyohiro Horikawa ,  Takahiro Watanabe ,  Kaoru Shigematsu ,  Yoshinori Amano ,  Shinichi Kojima

IPC分类号： G01N33/50

CPC分类号： G01N33/50 ,  A61B5/14532 ,  A61B2560/0252 ,  A61B2560/0456 ,  A61B2562/0295 ,  A61B2562/16 ,  A61B2562/18 ,  G01N27/3273

摘要： With this device for measuring a biological sample, a partition wall (14) is provided between a display section (2) and a sensor mount (5) inside a main case (1). A control board housing chamber (15) is disposed on the display unit (2) side of the partition wall (14), and a measurement board housing chamber (16) is disposed on the sensor mount (5) side of the partition wall (14). A control board (6) is housed in the control board housing chamber (15), and a measurement hoard (7) and a temperature sensor (13) are housed in the measurement board housing chamber (16).

摘要翻译： 利用这种用于测量生物样品的装置，在主壳体（1）内的显示部分（2）和传感器支架（5）之间设置有分隔壁（14）。 控制板容纳室（15）设置在分隔壁（14）的显示单元（2）侧，并且测量板容纳室（16）设置在分隔壁（5）的传感器安装件（5） 14）。 控制板（6）容纳在控制板容纳室（15）中，测量板（7）和温度传感器（13）容纳在测量板容纳室（16）中。

公开(公告)号：US08394085B2

公开(公告)日：2013-03-12

申请号：US12293621

申请日：2007-03-22

申请人： Kiyohiro Horikawa ,  Takeshi Nishida ,  Kenichi Hamanaka ,  Toshihiro Akiyama ,  Koji Miyoshi ,  Yoshinori Amano

发明人： Kiyohiro Horikawa ,  Takeshi Nishida ,  Kenichi Hamanaka ,  Toshihiro Akiyama ,  Koji Miyoshi ,  Yoshinori Amano

IPC分类号： A61B18/20

CPC分类号： A61B5/157 ,  A61B5/14535 ,  A61B5/1486 ,  A61B5/150022 ,  A61B5/150076 ,  A61B5/150099 ,  A61B5/150145 ,  A61B5/150213 ,  A61B5/150229 ,  A61B5/150259 ,  A61B5/150358 ,  A61B5/150755 ,  A61B5/150954 ,  A61B5/15138 ,  A61B5/6843

摘要： A laser perforation device that has a simple structure and with which pain to a person in skin perforation is reduced. In the device, a laser beam emitted from a laser emitting device is branched into laser beam paths by splitters and mirrors and pierces skin by applying the split beams to the same position on the skin. Since the skin is pierced by a laser beam with a low output, pain to the person can be reduced.

摘要翻译： 具有简单结构并且对皮肤穿孔者有疼痛的激光穿孔装置减少。 在该装置中，从激光发射装置发射的激光束通过分光镜和反射镜分支成激光束路径，并通过将分束施加到皮肤上的相同位置来刺穿皮肤。 由于皮肤被低输出的激光束穿透，所以可以减轻对人的疼痛。

公开(公告)号：US08221335B2

公开(公告)日：2012-07-17

申请号：US13171694

申请日：2011-06-29

申请人： Yoshinori Amano ,  Masaki Fujiwara

发明人： Yoshinori Amano ,  Masaki Fujiwara

IPC分类号： A61B5/00 ,  G01N1/00 ,  G01N33/50 ,  G01N27/26 ,  G01N21/75 ,  C12Q3/00

CPC分类号： A61B5/157 ,  A61B5/14532 ,  A61B5/14535 ,  A61B5/1486 ,  A61B5/150022 ,  A61B5/150099 ,  A61B5/150213 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/150519 ,  A61B5/150595 ,  A61B5/150641 ,  A61B5/150702 ,  A61B5/150755 ,  A61B5/15087 ,  A61B5/150954 ,  A61B5/15109 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/1513 ,  A61B5/1519 ,  A61B2562/0295

摘要： A blood test apparatus has a housing with an opening, and a plunger that moves back and forth inside the housing, the plunger having a projecting member. A fixing member fixes the plunger, which is provided in the housing. A blood sampling cartridge, in which a blood sensor, a puncturer, and a holder that holds the blood sensor and the puncturer, are integrated. The blood sampling cartridge is removably attached to the opening. The puncturer includes a lancet, one end of which is held by the plunger, and a blood collection needle attached to an other end of the lancet. A measuring circuit measures a signal obtained from the blood sensor to analyze components in the blood.

摘要翻译： 血液检查装置具有开口的壳体和在壳体内前后移动的柱塞，柱塞具有突出构件。 固定构件固定设置在壳体中的柱塞。 将血液传感器，穿刺器和保持血液传感器和穿刺器的保持器集成的采血管。 采血筒可拆卸地连接到开口。 穿刺器包括其一端由柱塞保持的刺血针和连接到刺血针另一端的采血针。 测量电路测量从血液传感器获得的信号，以分析血液中的成分。

公开(公告)号：US20120157881A1

公开(公告)日：2012-06-21

申请号：US13405631

申请日：2012-02-27

申请人： Toshiaki IIO ,  Yoshinori Amano ,  Koya Kurokawa ,  Noriyuki Shinohara

发明人： Toshiaki IIO ,  Yoshinori Amano ,  Koya Kurokawa ,  Noriyuki Shinohara

IPC分类号： A61B5/15

CPC分类号： A61B5/151 ,  A61B5/150022 ,  A61B5/150183 ,  A61B5/150305 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/150725 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/1519 ,  A61B5/15194

摘要： A lancet is pressed against a puncture needle cartridge while fitting a puncture needle loading inlet of the lancet to the axis of a puncture needle on the puncture needle cartridge. In order to facilitate the operation, one of plural puncture needles, arranged in parallel, is tilted up from its initial position at a predetermined angle, and the puncture needle is guided into a puncture needle holding rod of the lancet. Simultaneously, the puncture needle is pressed up to a position where the rear end part of the needle pushes the bottom surface of a puncture needle loading chamber of the puncture needle holding rod, whereby the puncture needle is loaded. When discarding a used puncture needle, the puncture needle is inserted into a lancet guide member of the puncture needle cartridge, whereby the puncture needle is reliably captured to be discarded.

摘要翻译： 将刺血针的穿刺针装载入口与穿刺针筒上的穿刺针的轴线嵌合时，将刺血针压在穿刺针筒上。 为了便于操作，平行布置的多个穿刺针中的一个从其初始位置以预定角度向上倾斜，并且穿刺针被引导到刺血针的穿刺针保持杆中。 同时，将穿刺针按压到针的后端推动穿刺针保持杆的穿刺针装载室的底面的位置，由此装载穿刺针。 当丢弃使用过的穿刺针时，将穿刺针插入到穿刺针筒的刺血针引导构件中，由此可靠地捕捉穿刺针以被丢弃。

公开(公告)号：US20110256572A1

公开(公告)日：2011-10-20

申请号：US13044046

申请日：2011-03-09

申请人： Yoshinori AMANO ,  Hideaki Hashimoto ,  Takeshi Nishida ,  Kazuyoshi Mori ,  Ryuuji Shimizu ,  Hiroshi Andou ,  Kenji Nakanishi ,  Naoki Yanagihara ,  Miho Hayashi

发明人： Yoshinori AMANO ,  Hideaki Hashimoto ,  Takeshi Nishida ,  Kazuyoshi Mori ,  Ryuuji Shimizu ,  Hiroshi Andou ,  Kenji Nakanishi ,  Naoki Yanagihara ,  Miho Hayashi

IPC分类号： C12Q1/02

CPC分类号： B01L3/502715 ,  B01L3/5025 ,  B01L2200/027 ,  B01L2300/0803 ,  B01L2300/0864 ,  B01L2300/1844 ,  B01L2400/0409 ,  G01N27/447

摘要： A plate on which a channel pattern is formed, which channel pattern includes a first channel into which a buffer agent is injected, and a second channel having, in a portion thereof, a quantification part that has a portion common to the first channel and holds a predetermined amount of a biological sample, the biological sample being injected into the channel including the quantification part, and the plate is rotated at a high speed by a filling unit to fill the buffer agent in the first channel, and thereafter, the second channel is pressurized by a discrimination unit to fill the biological sample in the second channel, and simultaneously, a predetermined amount of the biological sample is added into the buffer agent. Therefore, when performing discrimination of the biological sample, a discrimination result can be obtained accurately in a short time without the necessity of complicated preparation works.

摘要翻译： 其上形成有通道图案的板，哪个通道图案包括其中注入有缓冲剂的第一通道，以及第二通道，其在其一部分中具有量化部分，该量化部分具有与第一通道共同的部分 预定量的生物样品，将生物样品注入包括定量部分的通道中，并且板通过填充单元高速旋转以填充第一通道中的缓冲剂，然后第二通道 由识别单元加压以填充第二通道中的生物样品，同时将预定量的生物样品加入到缓冲剂中。 因此，当进行生物样品的鉴别时，可以在短时间内准确地获得鉴别结果，而不需要复杂的准备工作。

公开(公告)号：US08029525B2

公开(公告)日：2011-10-04

申请号：US10566434

申请日：2004-07-30

申请人： Toshiaki Iio ,  Yoshinori Amano ,  Seiji Kikuchi

发明人： Toshiaki Iio ,  Yoshinori Amano ,  Seiji Kikuchi

IPC分类号： A61B17/32

CPC分类号： A61B5/150198 ,  A61B5/150022 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/1513 ,  A61B5/15146 ,  A61B5/15153 ,  A61B5/15155 ,  A61B5/15174 ,  A61B50/362

摘要： An arrangement comprises a puncturing instrument including a cylindrical box, a plurality of puncturing needles held in an axially serially connected state, a locking member for locking the puncturing needle cartridge at an axial predetermined position, and an elastic urging member urging the puncturing needle cartridge in one direction, and a puncturing needle replacing jig which allows the setting of a puncturing position for the puncturing needle cartridge and the discarding of used puncturing needles, in order to enter into a subsequent puncturing action after the puncturing of the puncturing needle. Thus, it is an object to provide, in an instrument for puncturing the surface of a living body, a highly safe puncturing instrument set having a plurality of puncturing needles, capable of continuous puncturing action by a simple operation.

摘要翻译： 一种装置，包括：一个穿刺器具，包括一个圆柱形盒，多个穿刺针被保持在轴向串联连接的状态，一个锁定构件，用于将穿刺针筒锁定在一个轴向预定的位置;一个弹性推动构件， 一个方向，以及穿刺针更换夹具，其允许设置穿刺针筒的穿刺位置和丢弃使用的穿刺针，以便在穿刺针穿刺之后进入随后的穿刺动作。 因此，本发明的目的是提供一种具有多个穿刺针的高度安全的穿刺器具，能够通过简单的操作进行穿刺动作。

公开(公告)号：US20100210970A1

公开(公告)日：2010-08-19

申请号：US12669257

申请日：2008-07-18

申请人： Kiyohiro Horikawa ,  Yoshinori Amano ,  Toshiki Matsumoto

发明人： Kiyohiro Horikawa ,  Yoshinori Amano ,  Toshiki Matsumoto

IPC分类号： A61B5/00 ,  A61B17/34

CPC分类号： A61B5/157 ,  A61B5/14535 ,  A61B5/1486 ,  A61B5/150022 ,  A61B5/150099 ,  A61B5/150213 ,  A61B5/150358 ,  A61B5/150793 ,  A61B5/150824 ,  A61B5/150954 ,  A61B5/15109 ,  A61B5/15138 ,  A61B2560/0223

摘要： A piercing device, a blood inspection device, and a piercing method that facilitate timing management for piercing. The piercing device has a housing (22), a laser emission device (26) being piercing means provided in the housing (22), a holding section (25) provided facing the laser emission device (26), negative pressure means (28) for applying negative pressure to a negative pressure chamber (28a) provided at the holding section (25), an electric circuit section (27) for controlling the negative pressure means (28), a first skin sensor (28b) for causing the laser emission device (26) to prepare for operation, and a timer (27k) for automatically outputting a preparation-for-piercing-is-ready signal based on an output from the first skin sensor (28b). Based on the output from the timer (27k), the laser emission device (26) being the piercing means emits a laser beam (26h) to perform piercing.

摘要翻译： 穿刺装置，血液检查装置以及促进刺穿定时管理的刺穿方法。 刺穿装置具有壳体（22），设置在壳体（22）中的穿刺装置的激光发射装置（26），与激光发射装置（26）相对设置的保持部分（25），负压装置（28） 用于向设置在保持部分（25）处的负压室（28a）施加负压，用于控制负压装置（28）的电路部分（27），用于引起激光发射的第一皮肤传感器（28b） 装置（26）以及用于基于第一皮肤传感器（28b）的输出自动输出准备就绪信号的计时器（27k）。 基于来自定时器（27k）的输出，作为穿刺装置的激光发射装置（26）发射激光束（26h）以进行穿孔。

公开(公告)号：US07604118B2

公开(公告)日：2009-10-20

申请号：US11010475

申请日：2004-12-14

申请人： Toshiaki Iio ,  Yoshinori Amano ,  Koya Kurokawa ,  Noriyuki Shinohara

发明人： Toshiaki Iio ,  Yoshinori Amano ,  Koya Kurokawa ,  Noriyuki Shinohara

IPC分类号： A61B5/151 ,  B65D83/02 ,  G07F11/02

CPC分类号： A61B5/151 ,  A61B5/150022 ,  A61B5/150183 ,  A61B5/150305 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/150725 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/1519 ,  A61B5/15194

摘要： A lancet is pressed against a puncture needle cartridge while fitting a puncture needle loading inlet of the lancet to the axis of a puncture needle on the puncture needle cartridge. In order to facilitate the operation, one of plural puncture needles, arranged in parallel, is tilted up from its initial position at a predetermined angle, and the puncture needle is guided into a puncture needle holding rod of the lancet. Simultaneously, the puncture needle is pressed up to a position where the rear end part of the needle pushes the bottom surface of a puncture needle loading chamber of the puncture needle holding rod, whereby the puncture needle is loaded. When discarding a used puncture needle, the puncture needle is inserted into a lancet guide member of the puncture needle cartridge, whereby the puncture needle is reliably captured to be discarded.

摘要翻译： 将刺血针的穿刺针装载入口与穿刺针筒上的穿刺针的轴线嵌合时，将刺血针压在穿刺针筒上。 为了便于操作，平行布置的多个穿刺针中的一个从其初始位置以预定角度向上倾斜，并且穿刺针被引导到刺血针的穿刺针保持杆中。 同时，将穿刺针按压到针的后端推动穿刺针保持杆的穿刺针装载室的底面的位置，由此装载穿刺针。 当丢弃使用过的穿刺针时，将穿刺针插入到穿刺针筒的刺血针引导构件中，由此可靠地捕捉穿刺针以被丢弃。

公开(公告)号：US20090177117A1

公开(公告)日：2009-07-09

申请号：US12162627

申请日：2007-01-31

申请人： Yoshinori Amano ,  Masaki Fujiwara

发明人： Yoshinori Amano ,  Masaki Fujiwara

IPC分类号： A61B5/151

CPC分类号： A61B5/157 ,  A61B5/14532 ,  A61B5/14535 ,  A61B5/1486 ,  A61B5/150022 ,  A61B5/150099 ,  A61B5/150213 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/150519 ,  A61B5/150595 ,  A61B5/150641 ,  A61B5/150702 ,  A61B5/150755 ,  A61B5/15087 ,  A61B5/150954 ,  A61B5/15109 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/1513 ,  A61B5/1519 ,  A61B2562/0295

摘要： It is intended to provide a blood test apparatus whereby the vicinity of a site to be punctured for collecting the blood can be negatively pressurized and the negative pressurization can be conducted at an appropriate time without resorting to a special operation, thereby facilitating a blood test. More specifically speaking, a blood test apparatus which comprises: a housing having an opening: a puncture means located in the opening; a first sensing means whereby the contact of the front face of the opening with a site to be punctured is detected; a negative pressurization means whereby the inside of the opening is negatively pressurized; a blood sensor whereby the blood, that flows out from the punctured site having been punctured by the puncture means after negatively pressurizing the inside of the opening by the negative pressurization means, is collected; and a measurement circuit whereby a signal obtained from the blood sensor analyzing components in the blood is measured, wherein the negative pressurization means starts up when the first sensing means detects the contact of the front face of the opening with the site to be punctured.

摘要翻译： 目的在于提供一种血液检查装置，由此可以对要采集血液的被刺穿部位的附近进行负压加压，并且可以在适当的时间进行负压，而不需要特别的操作，从而便于血液检查。 更具体地说，一种血液检查装置，包括：具有开口的壳体;位于开口中的穿刺装置; 第一检测装置，其中检测开口的前表面与待刺破部位的接触; 负压加压装置，其中开口的内部被负压; 收集血液传感器，在血液传感器中收集从负压装置对开口内侧负压后从穿刺装置穿刺的穿刺部位流出的血液， 以及测量电路，由此测量从分析血液中的成分的血液传感器获得的信号，其中当第一感测装置检测到开口的前面与要刺穿的部位的接触时，负压装置启动。