Abstract:
The invention is directed to an expandable stent for implanting in a body lumen, such as a coronary artery, peripheral artery, or other body lumen. The invention provides for an intravascular stent having a plurality of cylindrical rings connected by links. The links between adjacent rings provide axial strength when subjected to longitudinal compressive forces.
Abstract:
Methods are disclosed including thermally processing a scaffold to increase the radial strength of the scaffold when the scaffold is deployed from a crimped state to a deployed state such as a nominal deployment diameter. The thermal processing may further maintain or increase the expansion capability of the scaffold when expanded beyond the nominal diameter.
Abstract:
Methods are disclosed including thermally processing a scaffold to increase the radial strength of the scaffold when the scaffold is deployed from a crimped state to a deployed state such as a nominal deployment diameter. The thermal processing may further maintain or increase the expansion capability of the scaffold when expanded beyond the nominal diameter.
Abstract:
A scaffold strut is shaped to improve hemocompatibility. The scaffold is made from a tube having variable wall thickness. Methods are disclosed for modifying the thickness of the tube in such a way as to achieve a reduced hemodynamic profile, but without significantly affecting strength properties in areas where stress concentrations exist when the scaffold is loaded.
Abstract:
An endoprosthesis for delivery in a body lumen can be configured to inhibit structural fatigue, crack formation, and elastic recoil while providing improved crimping and expansion uniformity and radial strength. As such, the endoprosthesis can include at least one multi-stage crest element connecting adjacent bar arms. The multi-stage crest element and, optionally, the connection or transition between the multi-stage crest element and the bar arms can form a plurality of undulations or curves to improve the distribution of the strains experienced by the endoprosthesis. The improved strain distribution can improve the structural integrity and prevent failure of the endoprosthesis.
Abstract:
Methods of treating coronary artery disease (CAD) with bioresorbable stents resulting in reduced angina or non-ischemic chest pain are described. Methods of treatment and devices for treatment of angina and post-procedural chest pain that include anti-angina agents incorporated into the device are disclosed.
Abstract:
A stent for implantation in a body lumen, comprising a plurality of rings, each ring being connected to an adjacent ring by at least one link, each ring including a plurality of peaks and valleys, wherein each peak is connected to an adjacent valley by a strut to provide an undulating pattern within each ring. Further, wherein each of a plurality of the struts comprise a first portion and a second portion; each portion has a thickness that is substantially constant throughout both first and second portions; and each portion has a width that is substantially constant throughout both first and second portions. The first portion is connected to the second portion through a reduced zone positioned at a mid-point of the strut, wherein the reduced zone has a minimum thickness between 30% and 80% of the thickness of the first and second portions.
Abstract:
A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold has a structure that produces a low late lumen loss when implanted within a peripheral vessel and also exhibits a high axial fatigue life. In a preferred embodiment the scaffold forms ring structures interconnected by links, where a ring has 12 crowns and at most two links connecting adjacent rings.
Abstract:
Methods are disclosed including thermally processing a scaffold to increase the radial strength of the scaffold when the scaffold is deployed from a crimped state to a deployed state such as a nominal deployment diameter. The thermal processing may further maintain or increase the expansion capability of the scaffold when expanded beyond the nominal diameter.
Abstract:
Delivery systems are disclosed for bioresorbable scaffolds that decrease in length when expanded to a deployment diameter that allow accurate positioning of the scaffold at a lesion. The scaffolds are mounted on a catheter that includes marker bands that are positioned interior to the proximal and distal edges of the crimped scaffold to anticipate the shortening of the scaffold upon deployment. Delivery systems are further disclosed for bioresorbable scaffolds that increase in length when expanded to a deployment diameter that allow accurate positioning of the scaffold at a lesion. The scaffolds are mounted on a catheter that includes marker bands that are positioned exterior to the proximal and distal edges of the crimped scaffold to anticipate the lengthening of the scaffold upon deployment.