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    METHOD AND DEVICE FOR MONITORING RETINOPATHY
    2.
    发明申请
    METHOD AND DEVICE FOR MONITORING RETINOPATHY 审中-公开
    用于监测再狭窄的方法和装置

    公开(公告)号：US20140320820A1

    公开(公告)日：2014-10-30

    申请号：US14266491

    申请日：2014-04-30

    Applicant: Agency for Science, Technology and Research ,  Singapore Health Services Pte Ltd

    Inventor： Saravana Kumar Kumarasamy ,  Tien Yin Wong ,  Barathi Veluchamy Amutha ,  Shyam Sunder Chaurasia

    IPC: A61B3/10 ,  A61B3/00

    CPC classification number: A61B3/0008 ,  A61B3/1025 ,  A61B3/112

    Abstract: There is provided a method of monitoring retinopathy in a subject. The method involves measuring autofluorescence of a retina in response to high intensity blue light and infra-red reflectance of the anterior region of an eye in response to high intensity infra-red light of the subject over a total time period to obtain an autofluorescence intensity profile and an infra-red reflectance intensity profile. The autofluorescence intensity profile and infra-red reflectance intensity profile are processed to obtain a pupillary light reflex measurement that is used to assess the retinopathy status of the retina.

    Abstract translation: 提供了一种监测受试者的视网膜病变的方法。 该方法涉及响应于高强度蓝光和眼睛前部区域的红外反射率响应于受试者的高强度红外光在总时间段内测量自发荧光以获得自发荧光强度分布 和红外线反射强度分布图。 处理自发荧光强度分布和红外反射强度分布，以获得用于评估视网膜视网膜病变状态的瞳孔光反射测量。

    Non-motorized optical multiplexing for the simultaneous detection of DNA target amplicons in a polymerase chain reaction solution
    3.
    发明授权
    Non-motorized optical multiplexing for the simultaneous detection of DNA target amplicons in a polymerase chain reaction solution 有权

    公开(公告)号：US10718012B2

    公开(公告)日：2020-07-21

    申请号：US15029616

    申请日：2014-10-14

    Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

    Inventor： Jackie Y. Ying ,  Saravana Kumar Kumarasamy

    IPC: G01J5/60 ,  C12Q1/686 ,  C12Q1/6825

    Abstract: A multiplexed polymerase chain reaction (PCR) DNA detection system and a method for DNA detection within the PCR system are provided. The PCR DNA detection system includes a color charge-coupled device (CCD) camera, fluorophore-quencher probes and an imaging chamber. The fluorophore-quencher probes are selected in response to fluorophores quenched by the fluorophore-quencher probes corresponding to three selected primary colors and peak channel responses of the CCD camera such that emission profiles of the fluorophores substantially match the three selected primary colors and peak emission profiles of the fluorophores correspond to the peak RGB channel responses of the CCD camera. A DNA sample and the fluorophore-quencher probes are located within the imaging chamber. The color CCD camera is focused on the imaging chamber for simultaneous detection of up to three targets from fluorescence of the DNA sample and the fluorophore-quencher probes.

    Microfluidic device
    4.
    发明授权
    Microfluidic device 有权

    公开(公告)号：US10449541B2

    公开(公告)日：2019-10-22

    申请号：US15025858

    申请日：2013-09-30

    Applicant: Agency for Science, Technology and Research

    Inventor： Jackie Y. Ying ,  Saravana Kumar Kumarasamy ,  Rensheng Deng

    IPC: B01L3/00 ,  C12Q1/689 ,  C12Q1/686

    Abstract: There is provided a microfluidic device comprising: a plurality of wells, each well having an inlet and an outlet, wherein the inlets are in fluid communication with one or more entry channels and the outlets are in fluid communication with one or more exit channels, wherein said outlet is connected to the exit channel via an outlet connecting channel and said inlet is connected to the entry channel via an inlet connecting channel wherein the dimension of the outlet connecting channel is configured such that the surface tension of a liquid comprised in the well prevents the release of the liquid through the outlet connecting channel. There is also provided a system, method and use of the device.

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