公开(公告)号：US20230356223A1

公开(公告)日：2023-11-09

申请号：US18195918

申请日：2023-05-10

Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

Inventor： Shireen GOH ,  Shan Mei TAN

IPC: B04B5/10 ,  C12M1/00 ,  B01D21/26 ,  C12M3/06 ,  C12M1/26 ,  B01L3/00 ,  B01D43/00

CPC classification number: B01L3/502753 ,  B01D21/265 ,  B01D43/00 ,  B01L3/502707 ,  B01L3/50273 ,  B01L3/502776 ,  B04B5/10 ,  C12M23/16 ,  C12M29/10 ,  C12M33/14 ,  C12M47/02 ,  B01L2200/027 ,  B01L2200/0652 ,  B01L2200/12 ,  B01L2300/0681 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2300/0877 ,  B01L2300/088 ,  B01L2400/0403 ,  B03B5/32

Abstract: An apparatus for microfiltration and a scalable method for manufacture of an inertial microfluidic device for such microfiltration apparatus are provided. The apparatus for microfiltration includes one or more inertial microfluidic devices, each including a plurality of spirals of a microfluidic channel. At least one of the inertial microfluidic devices is configured to utilize outer wall focusing for high volume fraction microfiltration of particles. The scalable method for manufacture of the inertial microfluidic device includes micromachining on a polycarbonate-based substrate a rectangular spiral microchannel having one or more input channels and a plurality of output channels configured to utilize high volume fraction outer wall focusing for microfiltration of particles.

公开(公告)号：US20190275521A1

公开(公告)日：2019-09-12

申请号：US16319276

申请日：2017-07-21

Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH

Inventor： Shireen GOH ,  Shan Mei TAN

IPC: B01L3/00 ,  B01D21/26 ,  B04B5/10 ,  C12M3/06 ,  C12M1/00 ,  C12M1/26

Abstract: An apparatus for microfiltration and a scalable method for manufacture of an inertial microfluidic device for such microfiltration apparatus are provided. The apparatus for microfiltration includes one or more inertial microfluidic devices, each including a plurality of spirals of a microfluidic channel. At least one of the inertial microfluidic devices is configured to utilize outer wall focusing for high volume fraction microfiltration of particles. In an embodiment, multiple inertial microfluidic devices are connected in sequence for combined inner wall and outer wall focusing. The scalable method for manufacture of the inertial microfluidic device includes micromachining on a polycarbonate-based substrate a rectangular spiral microchannel having one or more input channels and a plurality of output channels configured to utilize high volume fraction outer wall focusing for microfiltration of particles.