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公开(公告)号:US11793806B2
公开(公告)日:2023-10-24
申请号:US17221423
申请日:2021-04-02
Applicant: Agios Pharmaceuticals, Inc.
Inventor: Shin-San Michael Su , Lenny Dang
IPC: A61K31/535 , A61K31/496 , A61K31/4965 , A61K31/497 , A61P7/06 , C07D205/04 , C07D213/81 , C07D215/14 , C07D235/06 , C07D241/20 , C07D271/12 , C07D295/192 , C07D333/24 , C07D401/12 , C07D405/12 , C07D417/12 , C07C307/10 , C07D241/04 , A61K31/415 , A61K31/4406 , A61K31/47 , C07C13/04 , C07D307/14
CPC classification number: A61K31/496 , A61K31/497 , A61K31/4965 , A61K31/535 , A61P7/06 , C07C307/10 , C07D205/04 , C07D213/81 , C07D215/14 , C07D235/06 , C07D241/04 , C07D241/20 , C07D271/12 , C07D295/192 , C07D333/24 , C07D401/12 , C07D405/12 , C07D417/12 , A61K31/415 , A61K31/4406 , A61K31/47 , C07C13/04 , C07D307/14
Abstract: Described herein are methods for using compounds that activate pyruvate kinase.
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公开(公告)号:US20210220351A1
公开(公告)日:2021-07-22
申请号:US17221423
申请日:2021-04-02
Applicant: Agios Pharmaceuticals, Inc.
Inventor: Shin-San Michael Su , Lenny Dang
IPC: A61K31/496 , A61K31/535 , A61K31/4965 , A61K31/497 , A61P7/06 , C07D205/04 , C07D213/81 , C07D215/14 , C07D235/06 , C07D241/20 , C07D271/12 , C07D295/192 , C07D333/24 , C07D401/12 , C07D405/12 , C07D417/12 , C07C307/10 , C07D241/04
Abstract: Described herein are methods for using compounds that activate pyruvate kinase.
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公开(公告)号:US20170290825A1
公开(公告)日:2017-10-12
申请号:US15583412
申请日:2017-05-01
Applicant: Agios Pharmaceuticals, Inc.
Inventor: Shin-San Michael Su
IPC: A61K31/496 , C07C307/10 , C07D241/04
CPC classification number: A61K31/496 , A61K31/415 , A61K31/4406 , A61K31/47 , A61K31/4965 , A61K31/497 , A61K31/535 , C07C13/04 , C07C307/10 , C07D205/04 , C07D213/81 , C07D215/14 , C07D235/06 , C07D241/04 , C07D241/20 , C07D271/12 , C07D295/192 , C07D307/14 , C07D333/24 , C07D401/12 , C07D405/12 , C07D417/12
Abstract: Described herein are methods for using compounds that activate pyruvate kinase.
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公开(公告)号:US20200289502A1
公开(公告)日:2020-09-17
申请号:US16821101
申请日:2020-03-17
Applicant: Agios Pharmaceuticals, Inc.
Inventor: Shin-San Michael Su , Lenny Dang
IPC: A61K31/496 , A61K31/535 , A61K31/4965 , A61K31/497 , A61P7/06 , C07D205/04 , C07D213/81 , C07D215/14 , C07D235/06 , C07D241/20 , C07D271/12 , C07D295/192 , C07D333/24 , C07D401/12 , C07D405/12 , C07D417/12 , C07C307/10 , C07D241/04
Abstract: Described herein are methods for using compounds that activate pyruvate kinase.
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公开(公告)号:US20200281501A1
公开(公告)日:2020-09-10
申请号:US16790860
申请日:2020-02-14
Applicant: Agios Pharmaceuticals, Inc.
Inventor: Lenny Dang , Valeria Fantin , Stefan Gross , Hyun Gyung Jang , Shengfang Jin , Francesco G. Salituro , Jeffrey O. Saunders , Shin-San Michael Su , Katharine Yen
IPC: A61B5/055 , A61K31/41 , A61K31/426 , A61K45/06 , C12N15/113 , G01N33/574 , G16H40/63 , C12Q1/32 , C12Q1/6886
Abstract: Methods of treating and evaluating subjects having neoactive mutants are described herein.
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公开(公告)号:US09682080B2
公开(公告)日:2017-06-20
申请号:US14886750
申请日:2015-10-19
Applicant: AGIOS PHARMACEUTICALS, INC
Inventor: Shin-San Michael Su
IPC: A61K31/535 , C07D413/00 , A61K31/496 , A61K31/4965 , A61K31/497 , C07D205/04 , C07D213/81 , C07D215/14 , C07D235/06 , C07D241/20 , C07D271/12 , C07D295/192 , C07D333/24 , C07D401/12 , C07D405/12 , C07D417/12
CPC classification number: A61K31/496 , A61K31/415 , A61K31/4406 , A61K31/47 , A61K31/4965 , A61K31/497 , A61K31/535 , C07C13/04 , C07C307/10 , C07D205/04 , C07D213/81 , C07D215/14 , C07D235/06 , C07D241/04 , C07D241/20 , C07D271/12 , C07D295/192 , C07D307/14 , C07D333/24 , C07D401/12 , C07D405/12 , C07D417/12
Abstract: Described herein are methods for using compounds that activate pyruvate kinase.
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7.METHODS AND COMPOSITIONS FOR CELL-PROLIFERATION-RELATED DISORDERS 有权
Title translation: 细胞增殖相关疾病的方法和组合物公开(公告)号:US20170044620A1
公开(公告)日:2017-02-16
申请号:US15238161
申请日:2016-08-16
Applicant: AGIOS PHARMACEUTICALS, INC.
Inventor: Leonard Luan C. Dang , Stefan Gross , Hyun Gyung Jang , Shengfang Jin , Shin-San Michael Su , Craig Thompson
IPC: C12Q1/68 , A61K31/194
CPC classification number: C12Q1/6886 , A61K31/015 , A61K31/05 , A61K31/122 , A61K31/194 , A61K31/225 , A61K31/355 , A61K31/375 , A61K31/381 , A61K31/522 , A61K31/7004 , A61K31/713 , A61K38/063 , A61K38/44 , C12Q1/32 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/156
Abstract: Methods of treating and evaluating subjects having neoactive mutants of IDH (e.g., IDH1 or IDH2).
Abstract translation: 治疗和评估具有IDH(例如,IDH1或IDH2)的新生突变体的受试者的方法。
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公开(公告)号:US10711314B2
公开(公告)日:2020-07-14
申请号:US15963784
申请日:2018-04-26
Applicant: Agios Pharmaceuticals, Inc.
Inventor: Leonard Luan C. Dang , Stefan Gross , Hyun Gyung Jang , Shengfang Jin , Shin-San Michael Su , Craig Thompson
IPC: C12Q1/32 , C12Q1/6886 , A61K31/225 , A61K31/015 , A61K31/05 , A61K31/122 , A61K31/355 , A61K31/375 , A61K31/381 , A61K31/522 , A61K31/7004 , A61K31/713 , A61K38/06 , A61K38/44 , A61K31/194
Abstract: Methods of diagnosing subjects having a cell proliferation-related disorder or suspected of having a cell proliferation-related disorder associated with mutant IDH enzymes with 2HG neoactivity.
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公开(公告)号:US09982309B2
公开(公告)日:2018-05-29
申请号:US15238161
申请日:2016-08-16
Applicant: AGIOS PHARMACEUTICALS, INC.
Inventor: Leonard Luan C. Dang , Stefan Gross , Hyun Gyung Jang , Shengfang Jin , Shin-San Michael Su , Craig Thompson
IPC: A61K31/225 , C12Q1/68 , A61K31/015 , A61K31/05 , A61K31/122 , A61K31/355 , A61K31/375 , A61K31/381 , A61K31/522 , A61K31/7004 , A61K31/713 , A61K38/06 , A61K38/44 , C12Q1/32 , A61K31/194
CPC classification number: C12Q1/6886 , A61K31/015 , A61K31/05 , A61K31/122 , A61K31/194 , A61K31/225 , A61K31/355 , A61K31/375 , A61K31/381 , A61K31/522 , A61K31/7004 , A61K31/713 , A61K38/063 , A61K38/44 , C12Q1/32 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/156
Abstract: Methods of treating and evaluating subjects having neoactive mutants of IDH (e.g., IDH1 or IDH2).
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公开(公告)号:US09980961B2
公开(公告)日:2018-05-29
申请号:US15583412
申请日:2017-05-01
Applicant: Agios Pharmaceuticals, Inc.
Inventor: Shin-San Michael Su , Lenny Dang
IPC: A61K31/535 , C07D413/00 , A61K31/496 , C07D241/04 , C07C307/10 , A61K31/4406 , C07C13/04 , A61K31/47 , C07D307/14 , A61K31/415
CPC classification number: A61K31/496 , A61K31/415 , A61K31/4406 , A61K31/47 , A61K31/4965 , A61K31/497 , A61K31/535 , C07C13/04 , C07C307/10 , C07D205/04 , C07D213/81 , C07D215/14 , C07D235/06 , C07D241/04 , C07D241/20 , C07D271/12 , C07D295/192 , C07D307/14 , C07D333/24 , C07D401/12 , C07D405/12 , C07D417/12
Abstract: Described herein are methods for using compounds that activate pyruvate kinase.
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