公开(公告)号：US20240156768A1

公开(公告)日：2024-05-16

申请号：US18417754

申请日：2024-01-19

申请人： Alcresta Therapeutics, Inc.

发明人： Robert GALLOTTO ,  Greta L. LORING ,  Kenneth GARY ,  Edward S. PARK ,  David J. BROWN ,  Willem Robert Klaas SCHOEVAART ,  Michiel Christian Alexander van VLIET

IPC分类号： A61K31/202 ,  A23L33/00 ,  A23L33/12 ,  A61J15/00 ,  A61L29/04 ,  A61M5/14 ,  A61M5/142 ,  C12N9/20 ,  C12N11/06 ,  C12N11/087 ,  C12N11/089

CPC分类号： A61K31/202 ,  A23L33/00 ,  A23L33/12 ,  A23L33/40 ,  A61J15/0076 ,  A61L29/048 ,  A61M5/14 ,  A61M5/1413 ,  A61M5/142 ,  C12N9/20 ,  C12N11/06 ,  C12N11/087 ,  C12N11/089

摘要： Embodiments of the disclosure are drawn to an enteral feeding device for hydrolyzing triglycerides in a nutritional formula. The device may include a body housing a chamber, an inlet configured to fluidly couple with a source of nutritional formula, and an outlet configured to fluidly couple with an enteral feeding tube. The device may include a headspace and a plurality of particles contained within the chamber, wherein the lipase is covalently bonded to the plurality of particles. The device may include an inlet filter located between the inlet and the chamber, wherein the inlet filter contains a first plurality of openings, and an outlet filter located between the chamber and the outlet, wherein the outlet filter has a second plurality of openings smaller than the plurality of particles.

公开(公告)号：US20210283085A1

公开(公告)日：2021-09-16

申请号：US17332194

申请日：2021-05-27

申请人： Alcresta Therapeutics, Inc.

发明人： Robert GALLOTTO ,  Greta L. LORING ,  Kenneth GARY ,  Edward S. PARK ,  David J. BROWN ,  Willem Robert Klaas SCHOEVAART ,  Michiel Christian Alexander van VLIET

IPC分类号： A61K31/202 ,  A61L29/04 ,  A61M5/14 ,  A61M5/142 ,  C12N11/06 ,  C12N11/08 ,  A61J15/00 ,  A23L33/00 ,  A23L33/12 ,  C12N9/20

摘要： Embodiments of the disclosure are drawn to an enteral feeding device for hydrolyzing triglycerides in a nutritional formula. The device may include a body housing a chamber, an inlet configured to fluidly couple with a source of nutritional formula, and an outlet configured to fluidly couple with an enteral feeding tube. The device may include a headspace and a plurality of particles contained within the chamber, wherein the lipase is covalently bonded to the plurality of particles. The device may include an inlet filter located between the inlet and the chamber, wherein the inlet filter contains a first plurality of openings, and an outlet filter located between the chamber and the outlet, wherein the outlet filter has a second plurality of openings smaller than the plurality of particles.

公开(公告)号：US20170105903A1

公开(公告)日：2017-04-20

申请号：US15291530

申请日：2016-10-12

申请人： ALCRESTA THERAPEUTICS, INC.

发明人： Robert GALLOTTO ,  Greta L. LORING ,  Kenneth GARY ,  Edward S. PARK ,  David J. BROWN ,  Willem Robert Klaas SCHOEVAART ,  Michiel Christian Alexander van VLIET

IPC分类号： A61J15/00 ,  A61K9/00 ,  A61K31/202 ,  A61J3/00 ,  A61L29/04

CPC分类号： A61K31/202 ,  A23L33/00 ,  A23L33/12 ,  A23L33/40 ,  A61J15/0076 ,  A61L29/048 ,  A61M5/14 ,  A61M5/1413 ,  A61M5/142 ,  C12N9/20 ,  C12N11/06 ,  C12N11/08

摘要： Embodiments of the disclosure are drawn to an enteral feeding device for hydrolyzing triglycerides in a nutritional formula. The device may include a body housing a chamber, an inlet configured to fluidly couple with a source of nutritional formula, and an outlet configured to fluidly couple with an enteral feeding tube. The device may include a headspace and a plurality of particles contained within the chamber, wherein the lipase is covalently bonded to the plurality of particles. The device may include an inlet filter located between the inlet and the chamber, wherein the inlet filter contains a first plurality of openings, and an outlet filter located between the chamber and the outlet, wherein the outlet filter has a second plurality of openings smaller than the plurality of particles.