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1.发明授权P-Glu-D-Phe-Trp-Ser-Tyr-D-Arg-Leu-Arg-Pro-Gly-NH{HD 2 {B and intermediates 失效P-Glu-D-Phe-Trp-Ser-Tyr-D-Arg-Leu-Arg-Pro-Gly-NH {HD 2 {B和中间体
公开(公告)号：US3929759A
公开(公告)日：1975-12-30
申请号：US52059174
申请日：1974-11-04
Applicant: AMERICAN HOME PROD
Inventor： FOELL THEODORE J
IPC: A61K38/00 , C07K7/23 , C07C103/52 , A61K37/00
CPC classification number: C07K7/23 , A61K38/00 , Y10S514/80 , Y10S930/13 , Y10S930/28
Abstract: D-Phe2-D-Arg6-LRF, is described as well as its synthesis by solid phase techniques and novel intermediates formed by such synthesis. The novel decapeptide exhibits anti-ovulatory activity in mammals.
Abstract translation: 描述了D-Phe2-D-Arg6-LRF，以及其通过固相技术的合成和通过这种合成形成的新型中间体。 新癸酰胺在哺乳动物中表现出抗排卵活性。
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2.发明授权Method of inhibiting fertility in mammals using D{13 Phe{hu 2{b {13 D{13 Ala{hu 6{b {13 LRF 失效使用D {13 Phe {hu 2 {b {13 D {13 Ala {hu 6 {b {13 LRF））来抑制哺乳动物的生殖力的方法
公开(公告)号：US3890437A
公开(公告)日：1975-06-17
申请号：US48612474
申请日：1974-07-05
Applicant: AMERICAN HOME PROD
Inventor： FOELL THEODORE J , YARDLEY JOHN P
IPC: A61K38/00 , C07K7/23 , A61K27/00 , C07C103/52
CPC classification number: C07K7/23 , A61K38/00 , Y10S514/80 , Y10S930/13
Abstract: D-Phe2-D-Ala6-LRF, is described as well as its synthesis by solid phase techniques and novel intermediates formed by such synthesis. The novel decapeptide exhibits anti-ovulatory activity in mammals.
Abstract translation: 描述了D-Phe2-D-Ala6-LRF，以及其通过固相技术的合成和通过这种合成形成的新型中间体。 新癸酰胺在哺乳动物中表现出抗排卵活性。
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公开(公告)号：US3267005A
公开(公告)日：1966-08-16
申请号：US31818063
申请日：1963-10-23
Applicant: AMERICAN HOME PROD
Inventor： FOELL THEODORE J , GEORGE GREENSPAN , SMITH LELAND L
IPC: C12P33/00
CPC classification number: C12P33/00 , Y10S435/911 , Y10S435/929
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公开(公告)号：US3574196A
公开(公告)日：1971-04-06
申请号：US3574196D
申请日：1967-03-13
Applicant: AMERICAN HOME PROD
Inventor： FOELL THEODORE J , REES RICHARD W , SMITH HERCHEL
IPC: A61K31/568 , A61K31/5685 , A61K31/569 , A61K31/57 , A61K31/573 , C07J1/00 , C07J5/00 , C07J7/00 , C07J75/00 , C07C169/14 , C07C169/26
CPC classification number: A61K31/573 , A61K31/568 , A61K31/5685 , A61K31/569 , A61K31/57 , C07J1/00 , C07J5/00 , C07J7/00 , C07J75/00
Abstract: STEROIDS WITH $-1,4 A RINGS UNSUBSTITUTED IN THE 3-POSITION (I) AND HAVING ADRENOCORTICAL, PROGESTATIONAL, ANDROGENIC AND ANABOLIC ACTIVITY ARE PROVIDED BY REDUCING STEROIDAL $1,4-3-OLS (II) OR-ACYLATES (III). COMPOUNDS (II) ARE PROVIDED BY REDUCING STEROIDAL $1,4-3-ONES (IV) WITH ALUMINUM HYDRIDE IN THE COLD. COMPOUNDS (I) ALSO ARE PROVIDED BY REDUCING COMPOUNDS (IV) WITH WARM ALUMINUM HYDRIDE AND SEPARATING THEM FROM 1,3- AND 2,4DIENE BYPRODUCTS BY SELECTIVE REDUCTION OF THE BYPRODUCTS WITH LITHIUM IN AMMONIA.
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5.发明授权3-desoxy steroidal-1,4-diene lactones and spiroethers 失效3-DESOXY STEROIDAL-1,4-DIENE LACTONES和SPIROETHERS
公开(公告)号：US3455909A
公开(公告)日：1969-07-15
申请号：US3455909D
申请日：1968-05-29
Applicant: AMERICAN HOME PROD
Inventor： FOELL THEODORE J , REES RICHARD W , SMITH HERCHEL
IPC: C07J21/00 , C07J75/00 , C07C173/00 , C07C169/20
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Patent Agency Ranking
公开(公告)号：US3231589A
公开(公告)日：1966-01-25
申请号：US29770663
申请日：1963-07-25
Applicant: AMERICAN HOME PROD
Inventor： GEORGE GREENSPAN , SMITH LELAND L , FOELL THEODORE J , RICHARD REES
IPC: C12P33/00
CPC classification number: C12P33/00 , Y10S435/913
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7.发明授权Resolution of racemic delta4-3-keto-13beta-alkyl steroids by using corynebacterium siplex 失效通过使用棒状杆菌复合物拆分外消旋的δ4-3-酮基-13β-烷基类固醇
公开(公告)号：US3189528A
公开(公告)日：1965-06-15
申请号：US29765663
申请日：1963-07-25
Applicant: AMERICAN HOME PROD
Inventor： SMITH LELAND L , GEORGE GREENSPAN , FOELL THEODORE J
CPC classification number: C12P33/00 , C12P33/02 , Y10S435/843
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8.发明授权P-Glu-D-Phe-Trp-Ser-Tyr-D-Phee-Leu-Arg-Pro-Gly-NH2 and intermediates 失效P-Glu-D-Phe-Trp-Ser-Tyr-D-Phee-Leu-Arg-Pro-Gly-NH2和中间体
公开(公告)号：US3928307A
公开(公告)日：1975-12-23
申请号：US52038274
申请日：1974-11-04
Applicant: AMERICAN HOME PROD
Inventor： FOELL THEODORE J , YARDLEY JOHN P
IPC: A61K38/00 , C07K7/23 , C07C103/52 , A61K37/00
CPC classification number: C07K7/23 , A61K38/00 , Y10S514/80 , Y10S930/13 , Y10S930/28
Abstract: D-Phe2-D-Phe6-LRF, is described as well as its synthesis by solid phase techniques and novel intermediates formed by such synthesis. The novel decapeptide exhibits anti-ovulatory activity in mammals.
Abstract translation: 描述了D-Phe2-D-Phe6-LRF，以及其通过固相技术的合成和通过这种合成形成的新型中间体。 新癸酰胺在哺乳动物中表现出抗排卵活性。
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9.发明授权Process for the preparation of steroidal 1,4-dienes unsubstituted in the 3-position 失效制备在三位置不排除的甾体1,4-二烯的方法
公开(公告)号：US3479340A
公开(公告)日：1969-11-18
申请号：US3479340D
申请日：1967-08-01
Applicant: AMERICAN HOME PROD
Inventor： REES RICHARD W , FOELL THEODORE J , SMITH HERCHEL
IPC: C07J1/00 , C07J5/00 , C07J75/00 , C07C167/00 , A61K27/00 , C07C173/00
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10.发明授权
公开(公告)号：US3412112A
公开(公告)日：1968-11-19
申请号：US58603066
申请日：1966-10-12
Applicant: AMERICAN HOME PROD
Inventor： FOELL THEODORE J , REES RICHARD W , HERSCHEL SMITH
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