公开(公告)号：US10385011B2

公开(公告)日：2019-08-20

申请号：US15561585

申请日：2016-03-30

Applicant: AMOREPACIFIC CORPORATION

Inventor： Yung Hyup Joo ,  Soo Jeong Choi ,  Heung Soo Baek ,  Chang Seok Lee ,  Jeong Hwan Kim ,  Yongjin Kim ,  Hong-Ju Shin ,  Ho Sik Rho ,  Song Seok Shin ,  Jon Hwan Lee

IPC: A61K31/16 ,  C07C231/12 ,  C07C233/70 ,  A61K8/42 ,  A61K31/166 ,  A61Q19/02 ,  A23L29/00 ,  C07C235/48

Abstract: Disclosed are a novel benzoic acid amide derivative compound, an isomer thereof, a pharmaceutically acceptable salt thereof, a prodrug thereof, a hydrate thereof, or a solvate thereof. The novel compound and the like inhibit melanin production, prevent tyrosinase activity, and have an excellent skin whitening effect.

公开(公告)号：US09433593B1

公开(公告)日：2016-09-06

申请号：US15085628

申请日：2016-03-30

Applicant: Amorepacific Corporation

Inventor： Yung Hyup Joo ,  Heung Soo Baek ,  Jeong Hwan Kim ,  Chang Geun Yi ,  Hyung Jun Lim ,  Hong-Ju Shin ,  Yongjin Kim ,  Jon Hwan Lee

IPC: A61K31/166 ,  A61K9/20 ,  A61K9/16 ,  A61K9/06 ,  A23L1/30 ,  A61K9/00

CPC classification number: A61K31/166 ,  A23G1/42 ,  A23G3/36 ,  A23G4/12 ,  A23G9/36 ,  A23L33/00 ,  A23L33/10 ,  A23V2002/00 ,  A61K9/0014 ,  A61K9/06 ,  A61K9/1652 ,  A61K9/2059

Abstract: 5-Adamantan-1-yl-N-(2,4-dihydroxybenzyl)-2,4-dimethoxybenzamide disclosed in the present disclosure lacks toxicity and can exhibit superior anti-inflammatory effect. It exhibits superior anti-inflammatory effect, for example, by inhibiting the production of one or more of NO and PGE2, by inhibiting the activity of one or more of the transcription factors NF-κB and AP-1 or by inhibiting proinflammatory cytokines such as IL-1β.

Abstract translation: 本发明公开的5-金刚烷-1-基-N-（2,4-二羟基苄基）-2,4-二甲氧基苯甲酰胺缺乏毒性，可表现出优异的抗炎作用。 通过抑制一种或多种转录因子NF-κB和AP-1的活性或通过抑制促炎细胞因子，例如通过抑制NO和PGE2中的一种或多种的产生，显示出优异的抗炎作用 IL-1β。

公开(公告)号：US12128117B2

公开(公告)日：2024-10-29

申请号：US17049794

申请日：2019-04-26

Applicant: AMOREPACIFIC CORPORATION

Inventor： Yan Li ,  Soojin Lee ,  Yongjin Kim ,  Gi-Ra Yi ,  Yi-Rang Lim ,  Seung-hyun Kim

IPC: A61K8/02 ,  A61K8/06 ,  A61K8/25 ,  A61Q17/04

CPC classification number: A61K8/0279 ,  A61K8/062 ,  A61K8/25 ,  A61Q17/04 ,  A61K2800/262

Abstract: The present specification describes a method for manufacturing porous inorganic particles and a light-reflecting composition comprising porous inorganic particles. According to an embodiment of the present disclosure it is possible to provide a method for manufacturing porous inorganic particles capable of selective transmission or scattering of light having a specific wavelength range by controlling pore size and shell thickness.