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公开(公告)号:US11826946B2
公开(公告)日:2023-11-28
申请号:US17365024
申请日:2021-07-01
CPC classification number: B29C64/00 , B22F1/054 , B22F10/12 , B33Y10/00 , B33Y70/10 , H05K1/092 , B22F2301/255 , B22F2998/10 , B22F2999/00 , B22F2999/00 , B22F9/24 , B22F2202/11
Abstract: An additive manufacturing process for forming a metallic layer on the surface of the substrate includes fabricating a substrate from a polymerizable composition by a stereolithographic process, and contacting the reactive surface with an aqueous solution including a metal precursor. The metal precursor includes a metal, and the polymerizable composition includes a multiplicity of multifunctional components. Each multifunctional component includes a reactive moiety extending from a surface of the substrate to form a reactive surface. An interface between the reactive surface and the aqueous solution is selectively irradiated to form nanoparticles including the metal in a desired pattern. The nanoparticles are chemically coupled to the reactive surface by reactive moieties, thereby forming a metallic layer on the surface of the substrate.
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公开(公告)号:US20250130230A1
公开(公告)日:2025-04-24
申请号:US18691615
申请日:2022-09-27
Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY , UNIVERSITY OF WASHINGTON
Inventor: Chao Wang , Liangcai Gu , Xiahui Chen , Shoukai Kang , MD Ashif Ikbal , Zhi Zhao
IPC: G01N33/569 , G01N33/543 , G01N33/553
Abstract: Provided herein are methods of detecting severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in a sample. The methods include contacting the sample with a plurality of gold nanoparticles (AuNPs) and/or other plasmonic metal nanoparticles (MNPs) that are conjugated with at least two sets of antibodies, or antigen binding portions thereof, that binds to at least first and second epitopes of SARS-CoV-2 proteins, such as receptor-binding domain (RBDs) under conditions sufficient for the antibodies, or the antigen binding portions thereof, to bind to the first and second epitopes of the SARS-CoV-2 proteins in the sample to produce bound SARS-CoV-2 proteins. The methods also include detecting the SARS-CoV-2 proteins when aggregations of the bound SARS-CoV-2 proteins form with one another. Related compositions, reaction mixtures, devices, kits, and systems are also provided.
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公开(公告)号:US20190256770A1
公开(公告)日:2019-08-22
申请号:US16077435
申请日:2017-02-13
Inventor: Ximin He , Edward Kavazanjian , Nasser Hamdan , Zhi Zhao
Abstract: A soil stabilization method of forming an admixture of at least one hydrogel precursor and urease enzyme, and contacting at least a portion of the admixture with soil, and forming a hydrogel network in-situ within at least a portion of the soil, wherein at least a portion of the hydrogel network includes in-situ precipitated calcium carbonate. In some embodiments, at least a portion of the hydrogel network is formed in-situ by polymerizing the at least one hydrogel precursor in the presence of the urease enzyme.
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公开(公告)号:US20230405918A1
公开(公告)日:2023-12-21
申请号:US18360580
申请日:2023-07-27
CPC classification number: B29C64/00 , B33Y10/00 , H05K1/092 , B22F1/054 , B22F2999/00 , B22F10/12 , B22F2301/255 , B22F2998/10 , B33Y70/10
Abstract: An additive manufacturing process for forming a metallic layer on the surface of the substrate includes fabricating a substrate from a polymerizable composition by a stereolithographic process, and contacting the reactive surface with an aqueous solution including a metal precursor. The metal precursor includes a metal, and the polymerizable composition includes a multiplicity of multifunctional components. Each multifunctional component includes a reactive moiety extending from a surface of the substrate to form a reactive surface. An interface between the reactive surface and the aqueous solution is selectively irradiated to form nanoparticles including the metal in a desired pattern. The nanoparticles are chemically coupled to the reactive surface by reactive moieties, thereby forming a metallic layer on the surface of the substrate.
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公开(公告)号:US10794029B2
公开(公告)日:2020-10-06
申请号:US16077435
申请日:2017-02-13
Inventor: Ximin He , Edward Kavazanjian , Nasser Hamdan , Zhi Zhao
IPC: E02D3/12 , C09K17/50 , C04B14/28 , C04B24/14 , C04B26/22 , C04B26/28 , C04B103/00 , C04B111/00 , E21D9/00 , C09K3/22 , C08L5/00 , E21D9/06 , C08L1/26
Abstract: A soil stabilization method of forming an admixture of at least one hydrogel precursor and urease enzyme, and contacting at least a portion of the admixture with soil, and forming a hydrogel network in-situ within at least a portion of the soil, wherein at least a portion of the hydrogel network includes in-situ precipitated calcium carbonate. In some embodiments, at least a portion of the hydrogel network is formed in-situ by polymerizing the at least one hydrogel precursor in the presence of the urease enzyme.
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