公开(公告)号：US20150125942A1

公开(公告)日：2015-05-07

申请号：US14533373

申请日：2014-11-05

Applicant: AXION BIOSYSTEMS, INC.

Inventor： Robert Dixon Grier, JR. ,  Anthony Michael Nicolini ,  Colin Michael Arrowood ,  Swaminathan Rajaraman

IPC: C12M1/00 ,  C12M1/32 ,  G01N33/487

CPC classification number: C12M23/38 ,  C12M23/00 ,  C12M23/12 ,  C12M33/04 ,  C12M35/02 ,  C12M41/12 ,  C12M41/26 ,  C12M41/32 ,  C12M41/36 ,  C12M41/46 ,  C12M41/48 ,  G01N33/48728

Abstract: Devices, systems, and methods for facilitating placement of cells and materials in culture plates configured for high-throughput applications are provided. A culture system is provided with a culture plate having a lid for guiding placement of cells and materials in each individual culture well of a culture plate. The lid may provide for coupling to an electrophysiology culture plate comprising a biosensor plate and a biologic culture plate, where the biosensor plate underlies and is coupled to the culture well plate such that each biosensor is operatively coupled to one culture well of the plurality of culture wells. A containment device that physically influences the positioning of fluid received in the culture plate is also provided herein.

Abstract translation: 提供了用于促进细胞和材料在配置用于高通量应用的培养板中的放置的装置，系统和方法。 培养系统具有培养板，该培养板具有用于引导将细胞和材料放置在培养板的各个培养孔中的盖子。 盖子可以提供与包括生物传感器板和生物培养板的电生理学培养板的耦合，其中生物传感器板位于培养皿板下并且连接到培养皿板，使得每个生物传感器可操作地偶联到多个培养物的一个培养物 井。 本文还提供了物理地影响接收在培养板中的流体定位的容纳装置。

公开(公告)号：US20180163165A1

公开(公告)日：2018-06-14

申请号：US15888218

申请日：2018-02-05

Applicant: AXION BIOSYSTEMS, INC.

Inventor： Robert Dixon Grier, JR. ,  Anthony Michael Nicolini ,  Colin Michael Arrowood ,  Swaminathan Rajaraman

IPC: C12M1/00 ,  G01N33/487 ,  C12M1/36 ,  C12M1/34 ,  C12M1/42 ,  C12M1/26 ,  C12M1/32

CPC classification number: C12M23/38 ,  C12M23/00 ,  C12M23/12 ,  C12M33/04 ,  C12M35/02 ,  C12M41/12 ,  C12M41/26 ,  C12M41/32 ,  C12M41/36 ,  C12M41/46 ,  C12M41/48 ,  G01N33/48728

Abstract: Devices, systems, and methods for facilitating placement of cells and materials in culture plates configured for high-throughput applications are provided. A culture system is provided with a culture plate having a lid for guiding placement of cells and materials in each individual culture well of a culture plate. The lid may provide for coupling to an electrophysiology culture plate comprising a biosensor plate and a biologic culture plate, where the biosensor plate underlies and is coupled to the culture well plate such that each biosensor is operatively coupled to one culture well of the plurality of culture wells. A containment device that physically influences the positioning of fluid received in the culture plate is also provided herein.

公开(公告)号：US09885012B2

公开(公告)日：2018-02-06

申请号：US14533373

申请日：2014-11-05

Applicant: AXION BIOSYSTEMS, INC.

Inventor： Robert Dixon Grier, Jr. ,  Anthony Michael Nicolini ,  Colin Michael Arrowood ,  Swaminathan Rajaraman

IPC: B01L1/00 ,  B01L3/00 ,  C12M1/00 ,  G01N33/487 ,  C12M1/32 ,  C12M1/26 ,  C12M1/42 ,  C12M1/34 ,  C12M1/36

CPC classification number: C12M23/38 ,  C12M23/00 ,  C12M23/12 ,  C12M33/04 ,  C12M35/02 ,  C12M41/12 ,  C12M41/26 ,  C12M41/32 ,  C12M41/36 ,  C12M41/46 ,  C12M41/48 ,  G01N33/48728

Abstract: Devices, systems, and methods for facilitating placement of cells and materials in culture plates configured for high-throughput applications are provided. A culture system is provided with a culture plate having a lid for guiding placement of cells and materials in each individual culture well of a culture plate. The lid may provide for coupling to an electrophysiology culture plate comprising a biosensor plate and a biologic culture plate, where the biosensor plate underlies and is coupled to the culture well plate such that each biosensor is operatively coupled to one culture well of the plurality of culture wells. A containment device that physically influences the positioning of fluid received in the culture plate is also provided herein.