Patent search ap:("AbbVie Inc.") AND inv:"Jayanthy JAYANTH" Page 1

1.

发明申请
PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-a]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF 审中-公开

公开(公告)号：US20200181158A1

公开(公告)日：2020-06-11

申请号：US16787251

申请日：2020-02-11

Applicant: AbbVie Inc.

Inventor： Ayman ALLIAN , Jayanthy JAYANTH , Ben KLÜNDER , Mohamed-Eslam F. MOHAMED , Ahmed A. OTHMAN , Patrick J. MARROUM , Peter T. MAYER

IPC: C07D487/14 , A61K47/38 , A61K47/12 , A61K31/4985 , A61K9/00

Abstract: The present disclosure relates to processes for preparing (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide, solid state forms thereof, and corresponding pharmaceutical compositions, methods of treatment (including treatment of rheumatoid arthritis), kits, methods of synthesis, and products-by-process.

2.

发明申请
ACOUSTIC MIXING FOR AUTO GRANULATION 有权
Title translation: 用于自动成像的声学混合

公开(公告)号：US20170007600A1

公开(公告)日：2017-01-12

申请号：US15204217

申请日：2016-07-07

Applicant: AbbVie Inc.

Inventor： Ping X. GAO , Raimundo HO , Jayanthy JAYANTH , Samrat MUKHERJEE , Katherine E. PETERSON , John C. STRONG , Ping TONG , Geoff G. ZHANG

IPC: A61K31/505 , A61K9/16 , A61J3/02 , B01F15/00

CPC classification number: A61K31/505 , A61J3/02 , A61K9/1688 , B01F11/02 , B01F2215/0032

Abstract: A process for acoustically mixing a bulk drug substance involves the application of acoustic energy to drive an accelerative force in a mixing vessel containing the drug substance. The drug substance may be, for example, Elagolix.

Abstract translation: 用于声学混合散装药物的方法包括施加声能以驱动含有药物物质的混合容器中的加速力。药物可以是例如Elagolix。

3.

发明申请
PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-a]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF 有权

公开(公告)号：US20220073530A1

公开(公告)日：2022-03-10

申请号：US17527717

申请日：2021-11-16

Applicant: AbbVie Inc.

Inventor： Ayman ALLIAN , Jayanthy JAYANTH , Mohamed-Eslam F. MOHAMED , Mathew MULHERN , Fredrik Lars NORDSTROM , Ahmed A. OTHMAN , Michael J. ROZEMA , Lakshmi BHAGAVATULA , Patrick J. MARROUM , Peter T. MAYER , Ahmad Y. SHEIKH , Thomas B. BORCHARDT , Ben KLÜNDER

IPC: C07D487/14 , A61K9/00 , A61K31/4985 , A61K47/12 , A61K47/38

Abstract: The present disclosure relates to processes for preparing (3S,4R)-3-ethyl-4-3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide, solid state forms thereof, and corresponding pharmaceutical compositions, methods of treatment (including treatment of rheumatoid arthritis, ankylosing spondylitis, and psoriatic arthritis), kits, methods of synthesis, and products-by-process.

4.

发明申请
PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-alpla]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF 有权

公开(公告)号：US20180141955A1

公开(公告)日：2018-05-24

申请号：US15857892

申请日：2017-12-29

Applicant: AbbVie Inc.

Inventor： Jayanthy JAYANTH , Patrick J. Marroum , Peter T. Mayer , Mohamed-Eslam F. Mohamed , Ahmed A. Othman

IPC: C07D487/14 , A61K47/38 , A61K31/4985 , A61K9/00 , A61K47/12

CPC classification number: C07D487/14 , A61K9/0053 , A61K31/4985 , A61K47/12 , A61K47/38 , C07B2200/13

Abstract: The present disclosure relates to processes for preparing (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide, solid state forms thereof, and corresponding pharmaceutical compositions, methods of treatment (including treatment of rheumatoid arthritis), kits, methods of synthesis, and products-by-process.

5.

发明申请
PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-a]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF 有权

公开(公告)号：US20220251101A1

公开(公告)日：2022-08-11

申请号：US17717486

申请日：2022-04-11

Applicant: AbbVie Inc.

Inventor： Ayman ALLIAN , Jayanthy JAYANTH , Mohamed-Eslam F. MOHAMED , Mathew MULHERN , Fredrik Lars NORDSTROM , Ahmed A. OTHMAN , Michael J. ROZEMA , Lakshmi BHAGAVATULA , Patrick J. MARROUM , Peter T. MAYER , Ahmad Y. SHEIKH , Thomas B. BORCHARDT , Ben KLÜNDER

IPC: C07D487/14 , A61K9/00 , A61K31/4985 , A61K47/12 , A61K47/38

Abstract: The present disclosure relates to processes for preparing (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide, solid state forms thereof, and corresponding pharmaceutical compositions, methods of treatment (including treatment of rheumatoid arthritis and various spondyloarthritic conditions, including types of axial spondyloarthritis (axSpA)), kits, methods of synthesis, and products-by-process. In various aspects, provided are methods for treating active non-radiographic axSpA (nr-axSpA) and methods for treating active ankylosing spondylitis (AS).

6.

发明申请
PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-a]PYRROLO[2,3-e]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF 审中-公开

公开(公告)号：US20200317682A1

公开(公告)日：2020-10-08

申请号：US16905667

申请日：2020-06-18

Applicant: AbbVie Inc.

Inventor： Ayman ALLIAN , Thomas B. BORCHARDT , Jayanthy JAYANTH , Patrick J. MARROUM , Peter T. MAYER , Mathew M. MULHERN , Fredrik Lars Nordstrom , Ahmad Y. SHEIKH

IPC: C07D487/14 , A61K9/00 , A61K31/4985 , A61K47/12 , A61K47/38

Abstract: The present disclosure relates to processes for preparing (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide, solid state forms thereof, and corresponding pharmaceutical compositions, methods of treatment (including treatment of rheumatoid arthritis), kits, methods of synthesis, and products-by-process.

7.

发明申请
PROCESSES FOR THE PREPARATION OF (3S,4R)-3-ETHYL-4-(3H-IMIDAZO[1,2-A]PYRROLO[2,3-E]-PYRAZIN-8-YL)-N-(2,2,2-TRIFLUOROETHYL)PYRROLIDINE-1-CARBOXAMIDE AND SOLID STATE FORMS THEREOF 审中-公开

公开(公告)号：US20190315761A1

公开(公告)日：2019-10-17

申请号：US16453684

申请日：2019-06-26

Applicant: AbbVie Inc.

Inventor： Ayman ALLIAN , Jayanthy JAYANTH , Ben KLÜNDER , Mohamed-Eslam F. MOHAMED , Ahmed A. OTHMAN , Patrick J. MARROUM , Peter T. MAYER

IPC: C07D487/14 , A61K31/4985 , A61K9/00 , A61K47/38 , A61K47/12

Abstract: The present disclosure relates to processes for preparing (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide, solid state forms thereof, and corresponding pharmaceutical compositions, methods of treatment (including treatment of rheumatoid arthritis), kits, methods of synthesis, and products-by-process.

8.

发明申请
ACOUSTIC MIXING FOR AUTO GRANULATION 审中-公开

公开(公告)号：US20180235962A1

公开(公告)日：2018-08-23

申请号：US15957433

申请日：2018-04-19

Applicant: AbbVie Inc.

Inventor： Ping X. GAO , Raimundo HO , Jayanthy JAYANTH , Samrat MUKHERJEE , Katherine E. PETERSON , John C. STRONG , Ping TONG , Geoff ZHANG

IPC: A61K31/505 , A61K9/16 , B01F11/02 , A61J3/02

CPC classification number: A61K31/505 , A61K9/1688 , A61K31/513 , B01F11/02 , B01F2215/0032

Abstract: A process for acoustically mixing a bulk drug substance involves the application of acoustic energy to drive an accelerative force in a mixing vessel containing the drug substance. The drug substance may be, for example, Elagolix.