公开(公告)号：US10183117B2

公开(公告)日：2019-01-22

申请号：US14885916

申请日：2015-10-16

申请人： AbbVie Inc.

发明人： Wolfgang Fraunhofer ,  James Cameron ,  Linas P. Laurusonis

IPC分类号： A61M5/20 ,  A61M5/24 ,  A61M5/19 ,  A61M5/142

摘要： A wearable automatic injection device is provided for administering a final medicament to a patient. The wearable automatic injection device comprises a housing, an injection assembly for injecting the patient with the final medicament, a container holding a bulk intermediate medicament and a diluent to be mixed to form the medicament, and a mixing mechanism for mixing the bulk intermediate medicament and the diluent in the container to form the final medicament prior. A system for administering a final medicament to a patient is also provided. The system comprises a container, a mixing mechanism for mixing a bulk intermediate medicament and a diluent in the container to form the final medicament, and a wearable automatic injection device configured to receive the container.

公开(公告)号：US20220023544A1

公开(公告)日：2022-01-27

申请号：US17189162

申请日：2021-03-01

申请人： AbbVie Inc.

发明人： Philip D. Anderson ,  Joseph F. Julian ,  Linas P. Laurusonis ,  Sean Corrigan ,  William Fienup ,  Tomas Matusaitis ,  Chris Strahm

IPC分类号： A61M5/20 ,  A61M5/142 ,  A61M5/00 ,  A61M5/24 ,  A61M5/32

摘要： Exemplary embodiments provide wearable automatic injection devices for administering a therapeutic agent to a patient's body at fast, controlled rates, for example, in a single fast bolus. Exemplary embodiments also provide methods for assembling wearable automatic injection devices for administering a therapeutic agent to a patient at fast, controlled rates. Exemplary embodiments also provide methods for using wearable automatic injection devices for administering a therapeutic agent to a patient at fast, controlled rates.

公开(公告)号：US20190231978A1

公开(公告)日：2019-08-01

申请号：US16252080

申请日：2019-01-18

申请人： AbbVie Inc.

发明人： Wolfgang Fraunhofer ,  James Cameron ,  Linas P. Laurusonis

IPC分类号： A61M5/20 ,  A61M5/142 ,  A61M5/24 ,  A61M5/19

CPC分类号： A61M5/2066 ,  A61M5/14244 ,  A61M5/14248 ,  A61M5/19 ,  A61M5/2448 ,  A61M2005/206

摘要： A wearable automatic injection device is provided for administering a final medicament to a patient. The wearable automatic injection device comprises a housing, an injection assembly for injecting the patient with the final medicament, a container holding a bulk intermediate medicament and a diluent to be mixed to form the medicament, and a mixing mechanism for mixing the bulk intermediate medicament and the diluent in the container to form the final medicament prior. A system for administering a final medicament to a patient is also provided. The system comprises a container, a mixing mechanism for mixing a bulk intermediate medicament and a diluent in the container to form the final medicament, and a wearable automatic injection device configured to receive the container.

公开(公告)号：US20180250472A1

公开(公告)日：2018-09-06

申请号：US15966809

申请日：2018-04-30

申请人： AbbVie Inc.

发明人： Philip D. Anderson ,  Joseph F. Julian ,  Linas P. Laurusonis ,  Sean Corrigan ,  William Fienup ,  Tomas Matusaitis ,  Chris Strahm

IPC分类号： A61M5/20 ,  A61M5/142 ,  A61M35/00 ,  A61M5/32 ,  A61M5/24

CPC分类号： A61M5/2053 ,  A61M5/002 ,  A61M5/14248 ,  A61M5/1452 ,  A61M5/20 ,  A61M5/2466 ,  A61M5/3202 ,  A61M5/3232 ,  A61M5/3234 ,  A61M35/00 ,  A61M2005/14252 ,  A61M2005/247 ,  Y10T29/49826

摘要： Exemplary embodiments provide wearable automatic injection devices for administering a therapeutic agent to a patient's body at fast, controlled rates, for example, in a single fast bolus. Exemplary embodiments also provide methods for assembling wearable automatic injection devices for administering a therapeutic agent to a patient at fast, controlled rates. Exemplary embodiments also provide methods for using wearable automatic injection devices for administering a therapeutic agent to a patient at fast, controlled rates.

公开(公告)号：US09443445B2

公开(公告)日：2016-09-13

申请号：US13782797

申请日：2013-03-01

申请人： AbbVie Inc.

发明人： Linas P. Laurusonis ,  Philip D. Anderson ,  Matthew M. Widman ,  Timothy D. McLeroy

IPC分类号： G09B23/28

CPC分类号： G09B23/285 ,  G06F19/00

摘要： Exemplary embodiments of the present disclosure provide reusable training automatic injection training devices, and components thereof, to simulate and/or mimic an operation of an actual automatic injection device. Exemplary embodiments of the training device can provide audible instructions, which can be in different languages, output from circuitry associated with the training device. Exemplary embodiment of the training device can be a self-contained and portable device that mimics a shape, size, and function of an actual automatic injection device without including a needle or any drug on board. Exemplary embodiments can be implemented to train a user on an operation and/or usage of an actual automatic injection device using embodiments of the automatic injection training devices so that a user can practice an autoinjection without injecting a therapeutic agent, such as a liquid drug, into a recipient.

摘要翻译： 本公开的示例性实施例提供可重复使用的训练自动注射训练装置及其部件，以模拟和/或模拟实际自动注射装置的操作。 训练装置的示例性实施例可以提供可能以不同语言从与训练装置相关联的电路输出的可听指令。 训练装置的示例性实施例可以是独立且便携式的装置，其模拟实际自动注射装置的形状，尺寸和功能，而不包括针或任何药物在船上。 可以实施示例性实施例以使用自动注射训练装置的实施例来训练用户对实际自动注射装置的操作和/或使用，使得使用者可以在不注射诸如液体药物的治疗剂的情况下练习自动注射， 成为收件人

公开(公告)号：US20160106921A1

公开(公告)日：2016-04-21

申请号：US14885916

申请日：2015-10-16

申请人： AbbVie Inc.

发明人： Wolfgang Fraunhofer ,  James Cameron ,  Linas P. Laurusonis

IPC分类号： A61M5/20 ,  A61M5/19

CPC分类号： A61M5/2066 ,  A61M5/14244 ,  A61M5/14248 ,  A61M5/19 ,  A61M5/2448 ,  A61M2005/206

摘要： A wearable automatic injection device is provided for administering a final medicament to a patient. The wearable automatic injection device comprises a housing, an injection assembly for injecting the patient with the final medicament, a container holding a bulk intermediate medicament and a diluent to be mixed to form the medicament, and a mixing mechanism for mixing the bulk intermediate medicament and the diluent in the container to form the final medicament prior. A system for administering a final medicament to a patient is also provided. The system comprises a container, a mixing mechanism for mixing a bulk intermediate medicament and a diluent in the container to form the final medicament, and a wearable automatic injection device configured to receive the container.

摘要翻译： 提供一种可佩戴的自动注射装置，用于向患者施用最终药物。 可穿戴式自动注射装置包括壳体，用于向患者注射最终药剂的注射组件，容纳大量中间体药物的容器和待混合以形成药物的稀释剂，以及混合机构，用于混合本体中间体药物和 容器中的稀释剂以形成最终药物。 还提供了一种用于向患者施用最终药物的系统。 该系统包括容器，用于混合容器中的中间药物和稀释剂在容器中以形成最终药物的混合机构，以及构造成容纳容器的可穿戴自动注射装置。

公开(公告)号：US20140270897A1

公开(公告)日：2014-09-18

申请号：US14212229

申请日：2014-03-14

申请人： ABBVIE INC.

发明人： Linas P. Laurusonis ,  Edward Naguit Abante ,  Bryan Eliot Rolfs ,  Ramana Malladi ,  Bhimaprasad Medhal ,  James Blaine Wolford ,  Olivier Franck Currat ,  Martin Rathgeber ,  Kieron Hiuhon Tse

IPC分类号： B05C1/00

CPC分类号： B05C1/00 ,  A61M35/003 ,  B05B11/0067 ,  B05B11/007 ,  B05B11/0072 ,  B05B11/025 ,  B05B11/3004 ,  B05B11/3011 ,  B05B11/3015 ,  B05B11/3016 ,  B05B11/3054 ,  B05B11/3057 ,  B05B11/308 ,  B65D47/2031

摘要： Fluid applicators for use with topical medications are disclosed herein. An example apparatus includes a housing and a fluid container disposed inside the housing. The example apparatus also includes a pump assembly disposed inside the housing and fluidly coupled to the fluid container. The example apparatus further includes an applicator coupled to the housing. The applicator defines an outlet and has a surface to be in contact with an application site on a person. The surface is in fluid communication with the pump assembly via the outlet. The example apparatus also includes an actuator operatively coupled to the pump assembly. Movement of the actuator from a first position to a second position is to operate the pump to dispense a dose of the fluid onto the surface.

摘要翻译： 本文公开了用于局部用药的流体涂抹器。 示例性装置包括壳体和设置在壳体内部的流体容器。 示例性装置还包括设置在壳体内部并且流体耦合到流体容器的泵组件。 该示例设备还包括耦合到壳体的施加器。 施用器限定出口并且具有与人的施用部位接触的表面。 表面经由出口与泵组件流体连通。 示例性装置还包括可操作地联接到泵组件的致动器。 致动器从第一位置到第二位置的移动是操作泵以将一定剂量的流体分配到表面上。