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    Containers having closed ends, container assemblies and medical devices having such containers
    1.
    发明授权
    Containers having closed ends, container assemblies and medical devices having such containers 有权

    公开(公告)号：US11986636B2

    公开(公告)日：2024-05-21

    申请号：US16945464

    申请日：2020-07-31

    申请人： SCHOTT PHARMA SCHWEIZ AG

    发明人： Arne Kloke ,  Anil-Kumar Busimi ,  Dominique Bauert

    IPC分类号： A61M5/24 ,  A61J1/06 ,  A61M5/20

    CPC分类号： A61M5/2429 ,  A61M5/2033 ,  A61J1/065 ,  A61M2005/247

    摘要： Container assemblies for accommodating pharmaceutical compositions are provided. The container assembly includes a container and a plunger. The container has a hollow cylindrical body with an open end and a closed end, which is closed by a bottom portion. The hollow cylindrical body has a length (L), an outer diameter (DO), and an inner diameter with a length to outer diameter ratio between 3:1 and 15:1. The hollow cylindrical body and the bottom portion are formed integrally and of the same material, which is a glass or polymer material. The container has an inner surface with an average Zn-leachability of 0.00085 μg/cm2 or less. The plunger is inside the hollow cylindrical body at the open end, is pierceable by a cannula, and is slidable relative to the hollow cylindrical body from the open end towards the closed end.

    MOTION-ACTIVATED SEPTUM PUNCTURING DRUG DELIVERY DEVICE
    6.
    发明申请
    MOTION-ACTIVATED SEPTUM PUNCTURING DRUG DELIVERY DEVICE 审中-公开
    运动激活的冲击药物递送装置

    公开(公告)号：US20170035961A1

    公开(公告)日：2017-02-09

    申请号：US15235931

    申请日：2016-08-12

    申请人： MEDIMOP Medical Projects Ltd.

    发明人： Oz CABIRI

    IPC分类号： A61M5/142 ,  A61J1/14 ,  A61M5/145

    CPC分类号： A61M5/14248 ,  A61J1/1406 ,  A61M5/14244 ,  A61M5/1452 ,  A61M5/14566 ,  A61M5/158 ,  A61M5/172 ,  A61M5/283 ,  A61M5/3146 ,  A61M2005/14208 ,  A61M2005/14252 ,  A61M2005/14256 ,  A61M2005/14268 ,  A61M2005/14533 ,  A61M2005/14573 ,  A61M2005/1581 ,  A61M2005/247 ,  A61M2005/2474 ,  A61M2205/123

    摘要： A method and apparatus are disclosed for delivery of a drug to a recipient. In some embodiments, the delivery apparatus may unseal a drug containing reservoir. In some embodiments, the delivery rate may be controlled and/or adjustable. Optionally the apparatus may be disposable. Optionally, the apparatus may have a low profile and/or be wearable and/or attachable to the recipient. Optionally, discharge of the drug and/or unsealing of the reservoir may be driven by a plunger moving parallel to the base of the apparatus. Optionally, the apparatus may release a hypodermic needle into the recipient. Optionally, release of the hypodermic needle may be in a direction non-parallel and/or orthogonal to the direction of movement of the plunger. Optionally, prior to release, the hypodermic needle may be preserved in an aseptic state by a needle opening septum sealing a needle opening. Optionally, upon release, the hypodermic needle may pierce the needle opening septum.

    摘要翻译： 公开了将药物递送到接受者的方法和装置。 在一些实施方案中，递送装置可以开封含药物储存器。 在一些实施例中，输送速率可以被控制和/或可调节。 可选地，该装置可以是一次性的。 可选地，该装置可以具有低轮廓和/或可佩戴和/或可附接到接收者。 任选地，药物的排出和/或储存器的开封可以由平行于装置的底座移动的活塞驱动。 可选地，该装置可将皮下注射针释放到受体中。 任选地，皮下注射针的释放可以在与柱塞的移动方向不平行和/或正交的方向上。 任选地，在释放之前，皮下注射针可以通过密封针孔的针头开口隔膜保持在无菌状态。 任选地，在释放时，皮下注射针可以刺穿针头开口隔膜。

    Medicament Device
    7.
    发明申请
    Medicament Device 审中-公开
    药物装置

    公开(公告)号：US20170028132A1

    公开(公告)日：2017-02-02

    申请号：US15100251

    申请日：2014-12-01

    申请人： Becton, Dickinson and Company

    发明人： Richard Cronenberg ,  Abhijitsinh Raj ,  Matthieu Charvin ,  David Booth

    IPC分类号： A61M5/20 ,  A61M5/24 ,  A61M5/315

    CPC分类号： A61M5/20 ,  A61M5/142 ,  A61M5/1454 ,  A61M5/162 ,  A61M5/2455 ,  A61M5/2459 ,  A61M5/2466 ,  A61M5/31568 ,  A61M2005/206 ,  A61M2005/2414 ,  A61M2005/247

    摘要： A method for creating a sterile connection with a fluid in a container. The container has a sealing member sealing a first end of the container, and a barrier sealing a chamber in fluid communication with the sealing member. The method includes providing a valve sleeve assembly that includes a flexible sleeve having a barrier portion at an end of the flexible sleeve, a hollow first penetrator disposed within the flexible sleeve, and a hollow second penetrator at least partially disposed within the first penetrator. An interior of the flexible sleeve is sterile. The method also includes piercing the barrier portion and the barrier with the first penetrator, and displacing the second penetrator relative to the first penetrator and the sealing member to pierce the sealing member and establish the sterile connection with an interior of the container.

    摘要翻译： 一种用于与容器中的流体形成无菌连接的方法。 容器具有密封容器的第一端的密封构件，以及密封与密封构件流体连通的室的障碍物。 该方法包括提供一种阀套组件，该套筒组件包括柔性套筒，该柔性套筒在柔性套筒的端部具有阻挡部分，设置在柔性套管内的中空第一穿透器以及至少部分地设置在第一穿透器内的中空第二穿透器。 柔性套管的内部是无菌的。 该方法还包括用第一穿透器刺穿阻挡部分和屏障，并且使第二穿透器相对于第一穿透器和密封件移动以刺穿密封构件并与容器的内部建立无菌连接。

    DISPOSABLE SAFETY ANESTHETIC SYRINGE AND THE NEEDLE HUB THERETO
    8.
    发明申请
    DISPOSABLE SAFETY ANESTHETIC SYRINGE AND THE NEEDLE HUB THERETO 审中-公开
    安全的麻醉剂和麻醉剂

    公开(公告)号：US20160058948A1

    公开(公告)日：2016-03-03

    申请号：US14471784

    申请日：2014-08-28

    申请人： Horatio Yen

    发明人： Horatio Yen

    IPC分类号： A61M5/24 ,  A61M5/34

    CPC分类号： A61M5/2466 ,  A61M5/24 ,  A61M5/3134 ,  A61M5/34 ,  A61M5/343 ,  A61M2005/247 ,  A61M2005/3118 ,  A61M2005/312 ,  A61M2005/342

    摘要： The present invention discloses a disposable safety syringe that has a needle hub having an accommodating space therein for various purposes. More specifically, the present invention provides a needle hub, configured to an end of a barrel, wherein the needle hub comprises an internal needle, an external needle and a hub body. The hub body has an accommodating space formed therein, the internal needle is configured at a proximal end of the hub body, the external needle is configured at a distal end of the hub body, the internal needle and the external needle are connected to the accommodating space for various purposes. Furthermore, the present application further provides a multi-stage protector for avoiding needle prick accidents.

    摘要翻译： 本发明公开了一种一次性安全注射器，其具有用于各种目的的具有容纳空间的针座。 更具体地说，本发明提供了一种针筒，其构造成筒的端部，其中针座包括内针，外针和轮毂体。 轮毂体具有形成在其中的容纳空间，内针构造在轮毂体的近端，外针构造在轮毂体的远端，内针和外针连接到容纳 空间用于各种目的。 此外，本申请还提供了一种用于避免针刺事故的多级保护器。

    Drug delivery device
    10.
    发明授权
    Drug delivery device 有权
    给药装置

    公开(公告)号：US09180250B2

    公开(公告)日：2015-11-10

    申请号：US13503293

    申请日：2010-10-28

    申请人： Axel Teucher ,  Michael Jugl

    发明人： Axel Teucher ,  Michael Jugl

    IPC分类号： A61M5/24 ,  A61M5/315 ,  A61M5/31

    CPC分类号： A61M5/24 ,  A61M5/2466 ,  A61M5/31551 ,  A61M5/31561 ,  A61M5/31583 ,  A61M5/31585 ,  A61M2005/2407 ,  A61M2005/247 ,  A61M2005/2492 ,  A61M2005/3103 ,  A61M2005/3142 ,  A61M2005/3152

    摘要： The present invention relates to a drug delivery device for dispensing of a dose of a medicinal product, comprising, a housing, a drive mechanism comprising an axially displaceable piston rod to act on a piston of a cartridge containing the medicinal product to be dispensed, wherein the housing is adapted to support a piercing element which is adapted to penetrate a distal end face of the cartridge exclusively on demand. Furthermore, the drug delivery device comprises means for displacing the cartridge from a proximal stop position to a distal stop position in an axial direction and with respect to the housing, wherein in the distal stop position, the cartridge is connected to the piercing element and wherein in the proximal stop position, the cartridge is disconnected from the piercing element such that a fluid transfer between inside volume of the cartridge and the piercing element is interrupted.

    摘要翻译： 本发明涉及一种用于分配药物产品剂量的药物递送装置，包括：壳体，包括可轴向移位的活塞杆的驱动机构，用于作用于容纳待分配药物的药筒的活塞，其中 壳体适于支撑穿孔元件，该穿孔元件适于仅根据需要穿透墨盒的远端面。 此外，药物输送装置包括用于将药筒从近端停止位置沿轴向方向和相对于外壳移动到远端停止位置的装置，其中在远端停止位置，药筒连接到刺穿元件，并且其中 在近端停止位置，药筒与穿刺元件断开连接，使得药筒的内部体积与刺穿元件之间的流体转移被中断。