公开(公告)号：US08889166B2

公开(公告)日：2014-11-18

申请号：US12511843

申请日：2009-07-29

申请人： Achim Kunze ,  Markus Wimmer ,  Joshua J. Jacobs

发明人： Achim Kunze ,  Markus Wimmer ,  Joshua J. Jacobs

IPC分类号： A61F13/00 ,  A61L27/04 ,  A61L27/18 ,  A61L27/16 ,  A61F2/48 ,  A61F2/30 ,  A61F2/32 ,  A61F2/44 ,  A61F2/38

CPC分类号： A61F2/30 ,  A61F2/32 ,  A61F2/38 ,  A61F2/442 ,  A61F2002/30062 ,  A61F2002/488 ,  A61F2210/0004 ,  A61F2310/00035 ,  A61L27/047 ,  A61L27/16 ,  A61L27/18 ,  C08L23/06 ,  C08L71/12 ,  C08L71/00

摘要： A plastic implant device for a mammal that contains a rare earth metal compound tracer and a method for detecting degradation such as wear of the implanted device are disclosed. The tracer can also be present with a separate antioxidant or the tracer compound can be can be the salt of a C6-C22 unsaturated carboxylic acid. The rare earth metal compound tracer is released when the prosthetic is worn down or otherwise degraded in the mammalian body in which it was implanted. The presence and amount of released tracer present in a body fluid or tissue sample measured and is proportional to the degree of degradation of the implant.

公开(公告)号：US08889167B2

公开(公告)日：2014-11-18

申请号：US12576748

申请日：2009-10-09

申请人： Achim Kunze ,  Markus Wimmer ,  Joshua J. Jacobs

发明人： Achim Kunze ,  Markus Wimmer ,  Joshua J. Jacobs

IPC分类号： A61L27/04 ,  A61F2/30 ,  A61L27/16 ,  A61L27/18 ,  A61F2/38 ,  A61F2/44 ,  A61F2/48 ,  A61F2/32

CPC分类号： A61F2/30 ,  A61F2/32 ,  A61F2/38 ,  A61F2/442 ,  A61F2002/30062 ,  A61F2002/488 ,  A61F2210/0004 ,  A61F2310/00035 ,  A61L27/047 ,  A61L27/16 ,  A61L27/18 ,  C08L23/06 ,  C08L71/12 ,  C08L71/00

摘要： A plastic implant device for a mammal that contains a rare earth metal compound tracer and a method for detecting degradation such as wear of the implanted device are disclosed. The tracer can also be present with a separate antioxidant or the tracer compound can be can be the salt of a C6-C22 unsaturated carboxylic acid. The rare earth metal compound tracer is released when the prosthetic is worn down or otherwise degraded in the mammalian body in which it was implanted. The presence and amount of released tracer present in a body fluid or tissue sample measured and is proportional to the degree of degradation of the implant.

摘要翻译： 公开了一种用于含有稀土金属化合物示踪剂的哺乳动物的塑料植入装置和用于检测植入装置的磨损等降解的方法。 示踪剂也可以与单独的抗氧化剂一起存在，或示踪化合物可以是C6-C22不饱和羧酸的盐。 当假体在植入其中的哺乳动物体内磨损或降解时，稀释金属化合物示踪剂被释放。 测量体液或组织样本中释放的示踪剂的存在和量，并与植入物的降解程度成比例。