公开(公告)号：US20230157535A1

公开(公告)日：2023-05-25

申请号：US17921438

申请日：2021-04-25

Applicant: ADOM, ADVANCED OPTICAL TECHNOLOGIES LTD.

Inventor： Yoel COHEN ,  Ra'anan GEFEN ,  Yoel ARIELI ,  Lee BARNEA NEHOSHTAN ,  Naor DERI

IPC: A61B3/10 ,  A61B3/00

CPC classification number: A61B3/101 ,  A61B3/0025 ,  A61B3/0091 ,  A61B3/0083

Abstract: Systems and methods for detecting physical characteristics of a multilayered tissue of a subject, such as a tear film including analyzing received detector-output indicative of optical properties of light reflected or deflected from the respective multilayered tissue, to determine spectral properties of the multilayered tissue; and determining physical characteristics of the multilayered tissue by using multiple spectral models of the of the multilayered tissue, each model being associated with spectral properties indicative of different tissue characteristics, wherein physical characteristics of the multilayered tissue are determined by hierarchal determination of a best-fit model from the multiple spectral models.

公开(公告)号：US20220007933A1

公开(公告)日：2022-01-13

申请号：US17473839

申请日：2021-09-13

Applicant: AdOM, ADVANCED OPTICAL TECHNOLOGIES LTD.

Inventor： Yoel ARIELI ,  Yoel COHEN ,  Shlomi EPSTEIN ,  Dror ARBEL ,  Ra'anan GEFEN

IPC: A61B3/10 ,  A61B3/00 ,  G01J3/45 ,  G01B11/06 ,  G01B9/02 ,  A61B3/15 ,  G01J3/02 ,  G01J3/453

Abstract: Apparatus and methods are described for performing tear film structure measurement on a tear film of an eye of a subject. A broadband light source (100) is configured to generate broadband light. A spectrometer (250) is configured to measure a spectrum of light of the broadband light that is reflected from at least one spot on the tear film, the spot having a diameter of between 100 microns and 240 microns. A computer processor (28) is coupled to the spectrometer and configured to determine a characteristic of the tear film based upon the spectrum of light measured by the spectrometer. Other applications are also described.

公开(公告)号：US20220034716A1

公开(公告)日：2022-02-03

申请号：US17276265

申请日：2019-07-04

Applicant: ADOM, ADVANCED OPTICAL TECHNOLOGIES LTD.

Inventor： Yoel COHEN ,  Ra'anan GEFEN ,  Shlomi EPSTEIN ,  Yoel ARIELI

IPC: G01J3/02 ,  A61B3/107 ,  A61B3/00 ,  G01J3/45

Abstract: Apparatus and methods are described for calibrating an optical system that is used for measuring optical properties of a portion of a subjects body. During a calibration stage, a front surface of a calibration object (300) is illuminated, light reflected from a plurality of points on the calibration object (300) is detected, and intensities of the light reflected from the plurality of points on the calibration object (300) are measured. During a measurement stage, the portion of the subjects body is illuminated, and light reflected from the portion of the subjects body is detected. Measurements performed upon the light that was reflected from the portion of the subjects body are calibrated, using the measured intensities of the light reflected from the plurality of points on the calibration object (300). Other applications are also described.

公开(公告)号：US20190183333A1

公开(公告)日：2019-06-20

申请号：US16322083

申请日：2017-08-02

Applicant: AdOM, ADVANCED OPTICAL TECHNOLOGIES LTD.

Inventor： Yoel ARIELI ,  Yoel COHEN ,  Shlomi EPSTEIN ,  Dror ARBEL ,  Ra'anan GEFEN

IPC: A61B3/10 ,  A61B3/00 ,  A61B3/15 ,  G01B11/06 ,  G01B9/02 ,  G01J3/45

CPC classification number: A61B3/101 ,  A61B3/0025 ,  A61B3/1005 ,  A61B3/152 ,  G01B9/02044 ,  G01B11/0625 ,  G01B11/0675 ,  G01J3/45

Abstract: Apparatus and methods are described for performing tear film structure measurement on a tear film of an eye of a subject. A broadband light source (100) is configured to generate broadband light. A spectrometer (250) is configured to measure a spectrum of light of the broadband light that is reflected from at least one spot on the tear film, the spot having a diameter of between 100 microns and 240 microns. A computer processor (28) is coupled to the spectrometer and configured to determine a characteristic of the tear film based upon the spectrum of light measured by the spectrometer. Other applications are also described.