公开(公告)号：US20180070813A1

公开(公告)日：2018-03-15

申请号：US15802829

申请日：2017-11-03

Applicant: ADOM, Advanced Optical Technologies Ltd

Inventor： Yoel Arieli ,  Yoel Cohen ,  Shlomi Epstein ,  Dror Arbel ,  Ra'anan Gefen

IPC: A61B3/10 ,  A61B3/00 ,  A61B3/15 ,  G01B9/02 ,  G01B11/06 ,  G01N21/27 ,  G02B3/08

CPC classification number: A61B3/101 ,  A61B3/0025 ,  A61B3/10 ,  A61B3/1005 ,  A61B3/152 ,  G01B9/02021 ,  G01B9/02025 ,  G01B9/02027 ,  G01B9/02044 ,  G01B9/02087 ,  G01B9/0209 ,  G01B11/06 ,  G01B11/0625 ,  G01B11/0675 ,  G01B2290/45 ,  G01J3/00 ,  G01N21/274 ,  G01N2201/066 ,  G01N2201/127 ,  G02B3/08 ,  G06T2207/30041

Abstract: Apparatus and methods are described, for detecting the surface topography of a portion of a curved surface of an object. A beam of light is directed toward the surface from a broad angle of incidence with respect to an optical axis of a camera. Light reflected from the surface is received by the camera, via a narrow-angle aperture. One or more darkened regions in the received light are detected, and the surface topography of portion of the surface is detected at least partially in response to the detected darkened regions. Other applications are also described.

公开(公告)号：US09833139B1

公开(公告)日：2017-12-05

申请号：US15671413

申请日：2017-08-08

Applicant: ADOM, Advanced Optical Technologies Ltd

Inventor： Yoel Arieli ,  Yoel Cohen ,  Shlomi Epstein ,  Dror Arbel ,  Ra'anan Gefen

IPC: A61B3/14 ,  A61B3/10 ,  G02B3/08 ,  G01B9/02 ,  A61B3/00 ,  A61B3/15 ,  G01B11/06 ,  G01N21/27

CPC classification number: A61B3/101 ,  A61B3/0025 ,  A61B3/1005 ,  A61B3/152 ,  G01B9/02021 ,  G01B9/02025 ,  G01B9/02027 ,  G01B9/02044 ,  G01B9/02087 ,  G01B9/0209 ,  G01B11/06 ,  G01B11/0625 ,  G01B11/0675 ,  G01B2290/45 ,  G01N21/274 ,  G01N2201/066 ,  G01N2201/127 ,  G02B3/08

Abstract: Apparatus and methods are described for performing structure measurement on a tear film of an eye of a subject. At least a portion of a surface of the tear film is illuminated using a broadband light source. A spectrum of light of the broadband light that is reflected from at least one point of the tear film is measured, using a spectrometer. Color information for a plurality of points of the tear film is obtained, by imaging a field of view of the tear film using a color camera. Using a processing unit, data from the color camera and data from the spectrometer that are indicative of characteristics of the tear film are received, and based upon a combination of the data received from the color camera and the data received from the spectrometer, an output is generated that is indicative of a structure of the tear film.

公开(公告)号：US20170332897A1

公开(公告)日：2017-11-23

申请号：US15671413

申请日：2017-08-08

Applicant: ADOM, Advanced Optical Technologies Ltd

Inventor： Yoel Arieli ,  Yoel Cohen ,  Shlomi Epstein ,  Dror Arbel ,  Ra'anan Gefen

IPC: A61B3/10 ,  G01B9/02 ,  A61B3/00 ,  G01N21/27 ,  G01B11/06 ,  G02B3/08 ,  A61B3/15

CPC classification number: A61B3/101 ,  A61B3/0025 ,  A61B3/1005 ,  A61B3/152 ,  G01B9/02021 ,  G01B9/02025 ,  G01B9/02027 ,  G01B9/02044 ,  G01B9/02087 ,  G01B9/0209 ,  G01B11/06 ,  G01B11/0625 ,  G01B11/0675 ,  G01B2290/45 ,  G01N21/274 ,  G01N2201/066 ,  G01N2201/127 ,  G02B3/08

Abstract: Apparatus and methods are described for performing structure measurement on a tear film of an eye of a subject. At least a portion of a surface of the tear film is illuminated using a broadband light source. A spectrum of light of the broadband light that is reflected from at least one point of the tear film is measured, using a spectrometer. Color information for a plurality of points of the tear film is obtained, by imaging a field of view of the tear film using a color camera. Using a processing unit, data from the color camera and data from the spectrometer that are indicative of characteristics of the tear film are received, and based upon a combination of the data received from the color camera and the data received from the spectrometer, an output is generated that is indicative of a structure of the tear film.

公开(公告)号：US11965777B2

公开(公告)日：2024-04-23

申请号：US17276265

申请日：2019-07-04

Applicant: ADOM, ADVANCED OPTICAL TECHNOLOGIES LTD.

Inventor： Yoel Cohen ,  Ra'anan Gefen ,  Shlomi Epstein ,  Yoel Arieli

IPC: G01J3/02 ,  A61B3/00 ,  A61B3/107 ,  G01J3/45

CPC classification number: G01J3/0297 ,  A61B3/0008 ,  A61B3/107 ,  G01J3/45

Abstract: Apparatus and methods are described for calibrating an optical system that is used for measuring optical properties of a portion of a subjects body. During a calibration stage, a front surface of a calibration object (300) is illuminated, light reflected from a plurality of points on the calibration object (300) is detected, and intensities of the light reflected from the plurality of points on the calibration object (300) are measured. During a measurement stage, the portion of the subjects body is illuminated, and light reflected from the portion of the subjects body is detected. Measurements performed upon the light that was reflected from the portion of the subjects body are calibrated, using the measured intensities of the light reflected from the plurality of points on the calibration object (300). Other applications are also described.

公开(公告)号：US09757027B2

公开(公告)日：2017-09-12

申请号：US15227839

申请日：2016-08-03

Applicant: ADOM, Advanced Optical Technologies Ltd

Inventor： Yoel Arieli ,  Yoel Cohen ,  Shlomi Epstein ,  Dror Arbel ,  Ra'anan Gefen

IPC: A61B3/14 ,  A61B3/10 ,  G01B9/02 ,  G01B11/06 ,  A61B3/00 ,  A61B3/15 ,  G01N21/27 ,  G02B3/08

CPC classification number: A61B3/101 ,  A61B3/0025 ,  A61B3/1005 ,  A61B3/152 ,  G01B9/02021 ,  G01B9/02025 ,  G01B9/02027 ,  G01B9/02044 ,  G01B9/02087 ,  G01B9/0209 ,  G01B11/06 ,  G01B11/0625 ,  G01B11/0675 ,  G01B2290/45 ,  G01N21/274 ,  G01N2201/066 ,  G01N2201/127 ,  G02B3/08

Abstract: A system and method are described for performing tear film structure measurement. A broadband light source illuminates the tear film. A spectrometer measures respective spectra of reflected light from at least one point of the tear film. A color camera performs large field of view imaging of the tear film, so as to obtain color information for all points of the tear film imaged by the color camera. A processing unit calibrates the camera at the point measured by the spectrometer so that the color obtained by the camera at the point matches the color of the spectrometer at the same point. The processing unit determines, from the color of respective points of the calibrated camera, thicknesses of one or more layers of the tear film at the respective points. Other applications are also described.

公开(公告)号：US20160338585A1

公开(公告)日：2016-11-24

申请号：US15227839

申请日：2016-08-03

Applicant: ADOM, Advanced Optical Technologies Ltd

Inventor： Yoel Arieli ,  Yoel Cohen ,  Shlomi Epstein ,  Dror Arbel ,  Ra'anan Gefen

IPC: A61B3/10 ,  G01N21/27 ,  A61B3/00 ,  A61B3/15 ,  G02B3/08 ,  G01B11/06 ,  G01B9/02

CPC classification number: A61B3/101 ,  A61B3/0025 ,  A61B3/1005 ,  A61B3/152 ,  G01B9/02021 ,  G01B9/02025 ,  G01B9/02027 ,  G01B9/02044 ,  G01B9/02087 ,  G01B9/0209 ,  G01B11/06 ,  G01B11/0625 ,  G01B11/0675 ,  G01B2290/45 ,  G01N21/274 ,  G01N2201/066 ,  G01N2201/127 ,  G02B3/08

Abstract: A system and method are described for performing tear film structure measurement. A broadband light source illuminates the tear film. A spectrometer measures respective spectra of reflected light from at least one point of the tear film. A color camera performs large field of view imaging of the tear film, so as to obtain color information for all points of the tear film imaged by the color camera. A processing unit calibrates the camera at the point measured by the spectrometer so that the color obtained by the camera at the point matches the color of the spectrometer at the same point. The processing unit determines, from the color of respective points of the calibrated camera, thicknesses of one or more layers of the tear film at the respective points. Other applications are also described.

Abstract translation: 描述了进行泪膜结构测量的系统和方法。 宽带光源照亮泪膜。 光谱仪测量来自泪膜的至少一个点的反射光的各个光谱。 彩色照相机对泪膜进行大视野成像，以获得由彩色照相机成像的泪膜的所有点的颜色信息。 处理单元在由光谱仪测量的点处校准相机，使得在该点处由相机获得的颜色与同一点处的光谱仪的颜色匹配。 处理单元根据校准的相机的各个点的颜色确定各个点处的泪膜的一层或多层的厚度。 还描述了其它应用。

公开(公告)号：US12213733B2

公开(公告)日：2025-02-04

申请号：US17921438

申请日：2021-04-25

Applicant: ADOM, ADVANCED OPTICAL TECHNOLOGIES LTD.

Inventor： Yoel Cohen ,  Ra'anan Gefen ,  Yoel Arieli ,  Lee Barnea Nehoshtan ,  Naor Deri

IPC: A61B3/10 ,  A61B3/00

Abstract: Systems and methods for detecting physical characteristics of a multilayered tissue of a subject, such as a tear film including analyzing received detector-output indicative of optical properties of light reflected or deflected from the respective multilayered tissue, to determine spectral properties of the multilayered tissue; and determining physical characteristics of the multilayered tissue by using multiple spectral models of the of the multilayered tissue, each model being associated with spectral properties indicative of different tissue characteristics, wherein physical characteristics of the multilayered tissue are determined by hierarchal determination of a best-fit model from the multiple spectral models.

公开(公告)号：US12023099B2

公开(公告)日：2024-07-02

申请号：US17473839

申请日：2021-09-13

Applicant: AdOM, ADVANCED OPTICAL TECHNOLOGIES LTD.

Inventor： Yoel Arieli ,  Yoel Cohen ,  Shlomi Epstein ,  Dror Arbel ,  Ra'anan Gefen

IPC: A61B3/10 ,  A61B3/00 ,  A61B3/15 ,  G01B9/02 ,  G01B11/06 ,  G01J3/02 ,  G01J3/45 ,  G01J3/453

CPC classification number: A61B3/101 ,  A61B3/0025 ,  A61B3/1005 ,  A61B3/152 ,  G01B9/02044 ,  G01B11/0625 ,  G01B11/0675 ,  G01J3/0248 ,  G01J3/45 ,  G01J3/453 ,  G01J3/0229

Abstract: Apparatus and methods are described for performing tear film structure measurement on a tear film of an eye of a subject. A broadband light source (100) is configured to generate broadband light. A spectrometer (250) is configured to measure a spectrum of light of the broadband light that is reflected from at least one spot on the tear film, the spot having a diameter of between 100 microns and 240 microns. A computer processor (28) is coupled to the spectrometer and configured to determine a characteristic of the tear film based upon the spectrum of light measured by the spectrometer. Other applications are also described.

公开(公告)号：US11116394B2

公开(公告)日：2021-09-14

申请号：US16322083

申请日：2017-08-02

Applicant: AdOM, ADVANCED OPTICAL TECHNOLOGIES LTD.

Inventor： Yoel Arieli ,  Yoel Cohen ,  Shlomi Epstein ,  Dror Arbel ,  Ra'anan Gefen

IPC: A61B3/14 ,  A61B3/10 ,  A61B3/00 ,  G01J3/45 ,  G01B11/06 ,  G01B9/02 ,  A61B3/15 ,  G01J3/02 ,  G01J3/453

Abstract: Apparatus and methods are described for performing tear film structure measurement on a tear film of an eye of a subject. A broadband light source (100) is configured to generate broadband light. A spectrometer (250) is configured to measure a spectrum of light of the broadband light that is reflected from at least one spot on the tear film, the spot having a diameter of between 100 microns and 240 microns. A computer processor (28) is coupled to the spectrometer and configured to determine a characteristic of the tear film based upon the spectrum of light measured by the spectrometer. Other applications are also described.

公开(公告)号：US10456029B2

公开(公告)日：2019-10-29

申请号：US15802829

申请日：2017-11-03

Applicant: ADOM, Advanced Optical Technologies Ltd

Inventor： Yoel Arieli ,  Yoel Cohen ,  Shlomi Epstein ,  Dror Arbel ,  Ra'anan Gefen

IPC: A61B3/14 ,  A61B3/10 ,  G01B9/02 ,  G01B11/06 ,  A61B3/00 ,  A61B3/15 ,  G01N21/27 ,  G02B3/08 ,  G01J3/00

Abstract: Apparatus and methods are described, for detecting the surface topography of a portion of a curved surface of an object. A beam of light is directed toward the surface from a broad angle of incidence with respect to an optical axis of a camera. Light reflected from the surface is received by the camera, via a narrow-angle aperture. One or more darkened regions in the received light are detected, and the surface topography of portion of the surface is detected at least partially in response to the detected darkened regions. Other applications are also described.