公开(公告)号：US11808370B2

公开(公告)日：2023-11-07

申请号：US16929062

申请日：2020-07-14

Applicant: Agilent Technologies, Inc.

Inventor： Clemens Plachetka ,  Manfred Berndt ,  Konstantin Shoykhet

IPC: F16K29/00 ,  F16K11/00 ,  G01N30/16 ,  G01N30/34 ,  G01N30/80 ,  B01F33/452 ,  G01N30/02 ,  B01F101/23

CPC classification number: F16K19/00 ,  B01F33/452 ,  F16K29/00 ,  G01N30/16 ,  G01N30/34 ,  G01N30/80 ,  B01F2101/23 ,  G01N2030/027 ,  G01N2030/347

Abstract: A mixer for mixing a mobile phase in a sample separation device for separating a fluidic sample, wherein the mixer includes a fluid inlet for supplying the mobile phase to be mixed to a mixing volume, a movable body configured for rotating and axially moving in the mixing volume to thereby mix the mobile phase, and a fluid outlet for supplying the mixed mobile phase to a mobile phase consumer.

公开(公告)号：US20240280546A1

公开(公告)日：2024-08-22

申请号：US18649773

申请日：2024-04-29

Applicant: Agilent Technologies, Inc.

Inventor： Clemens Plachetka ,  Manfred Berndt ,  Konstantin Shoykhet ,  Tony Ziegler ,  Joachim-Richard Wagner

IPC: G01N30/06 ,  G01N1/00 ,  G01N30/32

CPC classification number: G01N30/06 ,  G01N30/32 ,  G01N2001/002 ,  G01N2030/065 ,  G01N2030/326

Abstract: A fluid supply device for providing a mobile phase for a sample separating device includes a supply path configured to provide a fluid for forming at least a part of the mobile phase, a fluid conveying unit configured to receive and pressurize the fluid from the supply path and to convey the fluid to the sample separating device, and a sterile filter disposed in the supply path upstream of the fluid conveying unit and configured to filter the fluid. The fluid supply device may include a pre-filter pump configured to push the fluid through the sterile filter and/or a buffer unit configured to buffer the fluid.

公开(公告)号：US12000808B2

公开(公告)日：2024-06-04

申请号：US17348531

申请日：2021-06-15

Applicant: Agilent Technologies, Inc.

Inventor： Clemens Plachetka ,  Konstantin Shoykhet ,  Tony Ziegler ,  Joachim-Richard Wagner ,  Manfred Berndt

IPC: B01D15/14 ,  G01N30/02 ,  G01N30/20 ,  G01N30/32 ,  G01N30/36

CPC classification number: G01N30/36 ,  B01D15/14 ,  G01N30/20 ,  G01N30/32 ,  G01N2030/027 ,  G01N2030/201

Abstract: A fluid supply device for providing a mobile phase for a sample separating device includes, a supply conduit for providing a fluid which forms at least a part of the mobile phase, a fluid valve which is fluidically coupled with the supply conduit and, depending on its switching state, enables or prevents a passing of the fluid from the supply conduit, an elastic buffer unit which is fluidically coupled upstream of the fluid valve with the supply conduit and which is configured for buffering the fluid, and a fluid conveying unit for conveying the fluid which passes the fluid valve.

公开(公告)号：US20220018815A1

公开(公告)日：2022-01-20

申请号：US17297908

申请日：2018-11-27

Applicant: Agilent Technologies, Inc.

Inventor： Clemens Plachetka

IPC: G01N30/34

Abstract: A fluid supply system, for supplying a mobile phase in a sample separation device for separating a fluidic sample in a separation path, includes a proportioning unit for proportioning multiple solvent components for composing the mobile phase, a fluid drive unit for driving the solvent components of the mobile phase, and a control unit for controlling the proportioning unit and the fluid drive unit so that an undefined portion of the mobile phase is removed from the mobile phase before delivering the mobile phase from the fluid drive unit to the separation path.

公开(公告)号：US20230194008A1

公开(公告)日：2023-06-22

申请号：US18083425

申请日：2022-12-16

Applicant: Agilent Technologies, Inc.

Inventor： Tony Ziegler ,  Joachim-Richard Wagner ,  Clemens Plachetka

IPC: F16K15/18 ,  F16K15/04

CPC classification number: F16K15/1823 ,  F16K15/044 ,  F16K15/048

Abstract: A fluidic valve includes a valve seat, a valve sealing body placeable at the valve seat when the fluidic valve is closed and being displaced with respect to the valve seat when the fluidic valve is open, a force transmission element coupled with the valve sealing body, and an actuator mechanism configured for actuating the force transmission element for triggering the valve sealing body to carry out an additional movement different from an opening movement and a closing movement of the valve sealing body.

公开(公告)号：US20230046809A1

公开(公告)日：2023-02-16

申请号：US17793010

申请日：2021-01-28

Applicant: Agilent Technologies, Inc.

Inventor： Clemens Plachetka

IPC: F16K11/02 ,  F16K11/052 ,  F16K31/52

Abstract: A rocker valve for opening or closing a fluid connection includes a valve chamber into which at least one opening feeds, a pivotally mounted rocker switch, and a membrane surface located between the rocker switch and the opening. By pivoting the rocker switch, the opening can be fluidically opened or closed relative to the valve chamber. The rocker valve further includes a sealing element that is located between the membrane surface and the opening when the rocker switch closes the opening relative to the valve chamber.

公开(公告)号：US20220168670A1

公开(公告)日：2022-06-02

申请号：US17539173

申请日：2021-11-30

Applicant: Agilent Technologies, Inc.

Inventor： Clemens Plachetka ,  Tony Ziegler ,  Joachim-Richard Wagner

IPC: B01D19/00 ,  B01D71/24 ,  B01D71/70

Abstract: A degasser for at least partially degassing a gas-containing liquid, in particular for a sample separation device, includes a liquid accommodation volume for accommodating the gas-containing liquid during degassing, a negative pressure chamber in which a negative pressure, compared to the liquid accommodation volume, is to be generated, a gas permeable membrane separating the liquid accommodation volume from the negative pressure chamber and arranged so that ultrasound forces at least part of gas of the gas-containing liquid to move through the membrane by a combination of the negative pressure and the ultrasound, and an ultrasound source including an electroactive material and configured for generating ultrasound for actuating the gas-containing liquid and/or the gas permeable membrane.

公开(公告)号：US20210389285A1

公开(公告)日：2021-12-16

申请号：US17348531

申请日：2021-06-15

Applicant: Agilent Technologies, Inc.

Inventor： Clemens Plachetka ,  Konstantin Shoykhet ,  Tony Ziegler ,  Joachim-Richard Wagner ,  Manfred Berndt

IPC: G01N30/36 ,  G01N30/20 ,  G01N30/32 ,  B01D15/14

Abstract: A fluid supply device for providing a mobile phase for a sample separating device includes, a supply conduit for providing a fluid which forms at least a part of the mobile phase, a fluid valve which is fluidically coupled with the supply conduit and, depending on its switching state, enables or prevents a passing of the fluid from the supply conduit, an elastic buffer unit which is fluidically coupled upstream of the fluid valve with the supply conduit and which is configured for buffering the fluid, and a fluid conveying unit for conveying the fluid which passes the fluid valve.

公开(公告)号：US12235249B2

公开(公告)日：2025-02-25

申请号：US17297908

申请日：2018-11-27

Applicant: Agilent Technologies, Inc.

Inventor： Clemens Plachetka

IPC: G01N30/34

Abstract: A fluid supply system, for supplying a mobile phase in a sample separation device for separating a fluidic sample in a separation path, includes a proportioning unit for proportioning multiple solvent components for composing the mobile phase, a fluid drive unit for driving the solvent components of the mobile phase, and a control unit for controlling the proportioning unit and the fluid drive unit so that an undefined portion of the mobile phase is removed from the mobile phase before delivering the mobile phase from the fluid drive unit to the separation path.

公开(公告)号：US12140232B2

公开(公告)日：2024-11-12

申请号：US17793010

申请日：2021-01-28

Applicant: Agilent Technologies, Inc.

Inventor： Clemens Plachetka

IPC: F16K31/52 ,  F16K11/02 ,  F16K11/052

Abstract: A rocker valve for opening or closing a fluid connection includes a valve chamber into which at least one opening feeds, a pivotally mounted rocker switch, and a membrane surface located between the rocker switch and the opening. By pivoting the rocker switch, the opening can be fluidically opened or closed relative to the valve chamber. The rocker valve further includes a sealing element that is located between the membrane surface and the opening when the rocker switch closes the opening relative to the valve chamber.