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1.发明申请Process and methods for the preparation of optically active cis-2-hydroxymethyl-4- (cytosin-1'-yl) -1,3-oxathiolane or pharmaceutically acceptable salts thereof 有权用于制备光学活性顺式-2-羟甲基-4-（细胞蛋白酶-1'-基）-1,3-氧硫杂环戊烷的方法和方法或其药学上可接受的盐公开(公告)号：US20060199786A1
公开(公告)日：2006-09-07
申请号：US11073020
申请日：2005-03-07
申请人： Alex Cimpoia , Dan Simion , Ioana Simion
发明人： Alex Cimpoia , Dan Simion , Ioana Simion
IPC分类号： A61K31/513 , A61K31/675 , C07D409/02 , C07F9/6512
CPC分类号： C07D411/04 , C07F9/65586
摘要： There is provided a method for resolving a compound of formula III, in the cis configuration: There is also provided a process for producing optically active compound of formula I or II: wherein: R1, R2, R3 are as defined herein, the method and process involving the production, recovery and conversion of diastereomeric salts.
摘要翻译： 提供了以顺式构型分解式III化合物的方法：还提供了制备式I或II的光学活性化合物的方法：其中：R 1，R SUB R 2，R 3，R 3和R 3如本文所定义，涉及非对映异构体盐的生产，回收和转化的方法和方法。
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2.发明授权Process and methods for the preparation of optically active cis-2-hydroxymethyl-4- (cytosin-1'-yl)-1,3-oxathiolane or pharmaceutically acceptable salts thereof 有权用于制备光学活性顺式-2-羟甲基-4-（细胞蛋白酶-1'-基）-1,3-氧硫杂环戊烷的方法和方法或其药学上可接受的盐公开(公告)号：US07968703B2
公开(公告)日：2011-06-28
申请号：US11073020
申请日：2005-03-07
发明人： Alex Cimpoia , Dan Simion
IPC分类号： C07D411/04 , C07D239/47 , A61K31/506 , A61K31/513 , A61K31/7072 , A61P31/18
CPC分类号： C07D411/04 , C07F9/65586
摘要： There is provided a method for resolving a compound of formula III, in the cis configuration: There is also provided a process for producing optically active compound of formula I or II: wherein: R1, R2, R3 are as defined herein, the method and process involving the production, recovery and conversion of diastereomeric salts.
摘要翻译： 提供了以顺式构型分解式III化合物的方法：还提供了制备式I或II的旋光活性化合物的方法：其中：R1，R2，R3如本文所定义，该方法和 涉及非对映体盐的生产，回收和转化的方法。
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3.发明申请Process and methods for the preparation of optically active cis-2-hydroxymethyl-4-(cytosin-1'-yl)-1,3-oxathiolane or pharmaceutically acceptable salts thereof 有权用于制备光学活性顺式-2-羟甲基-4-（细胞蛋白酶-1'-基）-1,3-氧硫杂环戊烷的方法和方法或其药学上可接受的盐公开(公告)号：US20110257397A1
公开(公告)日：2011-10-20
申请号：US13166242
申请日：2011-06-22
申请人： Alex CIMPOIA , Dan Simion , Joana R. Simion
发明人： Alex CIMPOIA , Dan Simion , Joana R. Simion
IPC分类号： C07D411/04
CPC分类号： C07D411/04 , C07F9/65586
摘要： There is provided a method for resolving a compound of formula III, in the cis configuration: There is also provided a process for producing optically active compound of formula I or II: wherein: R1, R2, R3 are as defined herein, the method and process involving the production, recovery and conversion of diastereomeric salts.
摘要翻译： 提供了以顺式构型分解式III化合物的方法：还提供了制备式I或II的旋光活性化合物的方法：其中：R1，R2，R3如本文所定义，该方法和 涉及非对映体盐的生产，回收和转化的方法。
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4.发明授权Process and methods for the preparation of optically active cis-2-hydroxymethyl-4-(cytosin-1′-yl)-1,3-oxathiolane or pharmaceutically acceptable salts thereof 有权用于制备光学活性顺式-2-羟甲基-4-（细胞蛋白酶-1'-基）-1,3-氧硫杂环戊烷的方法和方法或其药学上可接受的盐公开(公告)号：US08399655B2
公开(公告)日：2013-03-19
申请号：US13166242
申请日：2011-06-22
申请人： Alex Cimpoia , Joana R. Simion
发明人： Alex Cimpoia , Dan Simion
IPC分类号： C07D411/04 , C07D239/47 , A61K31/506 , A61K31/513 , A61K31/7072 , A61P31/18
CPC分类号： C07D411/04 , C07F9/65586
摘要： There is provided a method for resolving a compound of formula III, in the cis configuration: There is also provided a process for producing optically active compound of formula I or II: wherein: R1, R2, R3 are as defined herein, the method and process involving the production, recovery and conversion of diastereomeric salts.
摘要翻译： 提供了以顺式构型分解式III化合物的方法：还提供了制备式I或II的旋光活性化合物的方法：其中：R1，R2，R3如本文所定义，该方法和 涉及非对映体盐的生产，回收和转化的方法。
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公开(公告)号：US07750604B2
公开(公告)日：2010-07-06
申请号：US11899913
申请日：2007-09-07
CPC分类号： H01M10/44 , H02J7/0093 , H02J7/045
摘要： Circuits and methods for battery charging are disclosed. In one embodiment, the battery charging circuit comprises an AC to DC converter, a charging control switch, and a charger controller. The AC to DC converter provides a charging power to a battery pack. The charging control switch is coupled between the AC to DC converter and the battery pack. The charging control switch transfers the charging power to the battery pack. The charger controller detects a battery status of the battery pack and controls the charging control switch to charge the battery pack in a continuous charging mode or a pulse charging mode according to the battery status. The charger controller also controls the AC to DC converter to regulate the charging power according to the battery status.
摘要翻译： 公开了用于电池充电的电路和方法。 在一个实施例中，电池充电电路包括AC至DC转换器，充电控制开关和充电器控制器。 AC到DC转换器为电池组提供充电电源。 充电控制开关耦合在AC到DC转换器和电池组之间。 充电控制开关将充电电力传送到电池组。 充电器控制器检测电池组的电池状态，并根据电池状态控制充电控制开关以连续充电模式或脉冲充电模式对电池组充电。 充电器控制器还控制AC到DC转换器，以根据电池状态调节充电功率。
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公开(公告)号：US08450977B2
公开(公告)日：2013-05-28
申请号：US12336783
申请日：2008-12-17
申请人： Marian Niculae , Alexandru Hartular , Dan Simion , Guoying Yi
发明人： Marian Niculae , Alexandru Hartular , Dan Simion , Guoying Yi
IPC分类号： H02J7/00
CPC分类号： H03K3/012 , H02J7/0068 , H02M1/08 , H03K17/6874
摘要： A driving circuit for an N-channel Metal Oxide Semiconductor (NMOS) transistor can include a charge pump unit and a driver coupled to the charge pump. The charge pump can receive a source voltage and output an output voltage higher than the source voltage, where the source voltage is applied to a source terminal of the NMOS transistor. The driver receives the output voltage of the charge pump unit and converts the output voltage to a driving voltage operable for conducting the NMOS transistor.
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公开(公告)号：US08289731B2
公开(公告)日：2012-10-16
申请号：US11810472
申请日：2007-06-05
CPC分类号： H02M3/335 , H02M2001/0006
摘要： A converter controller is disclosed. In one embodiment, a controller for a flyback converter includes a converter and a flyback controller. The converter is coupled to the flyback converter for receiving an auxiliary voltage and for generating a constant power voltage. The flyback controller is powered by the constant power voltage for controlling an output voltage of the flyback converter. Furthermore, the flyback converter comprises a transformer with a primary side and a secondary side. The output voltage and the auxiliary voltage are produced at the transformer.
摘要翻译： 公开了一种转换器控制器。 在一个实施例中，用于反激式转换器的控制器包括转换器和回扫控制器。 转换器耦合到反激转换器，用于接收辅助电压并产生恒定功率电压。 反激控制器由用于控制反激式转换器的输出电压的恒定电源电压供电。 此外，反激式转换器包括具有初级侧和次级侧的变压器。 变压器产生输出电压和辅助电压。
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公开(公告)号：US20100264882A1
公开(公告)日：2010-10-21
申请号：US12824411
申请日：2010-06-28
IPC分类号： H02J7/10
CPC分类号： H01M10/44 , H02J7/0093 , H02J7/045
摘要： Circuits and methods for battery charging are disclosed. In one embodiment, the battery charging circuit comprises an AC to DC converter, a charging control switch, and a charger controller. The AC to DC converter provides a charging power to a battery pack. The charging control switch is coupled between the AC to DC converter and the battery pack. The charging control switch transfers the charging power to the battery pack. The charger controller detects a battery status of the battery pack and controls the charging control switch to charge the battery pack in a continuous charging mode or a pulse charging mode according to the battery status. The charger controller also controls the AC to DC converter to regulate the charging power according to the battery status.
摘要翻译： 公开了用于电池充电的电路和方法。 在一个实施例中，电池充电电路包括AC至DC转换器，充电控制开关和充电器控制器。 AC到DC转换器为电池组提供充电电源。 充电控制开关耦合在AC到DC转换器和电池组之间。 充电控制开关将充电电力传送到电池组。 充电器控制器检测电池组的电池状态，并根据电池状态控制充电控制开关以连续充电模式或脉冲充电模式对电池组充电。 充电器控制器还控制AC到DC转换器，以根据电池状态调节充电功率。
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公开(公告)号：US20090160500A1
公开(公告)日：2009-06-25
申请号：US12336783
申请日：2008-12-17
申请人： Marian Niculae , Alexandru Hartular , Dan Simion , Guoying Yi
发明人： Marian Niculae , Alexandru Hartular , Dan Simion , Guoying Yi
IPC分类号： H03B1/00
CPC分类号： H03K3/012 , H02J7/0068 , H02M1/08 , H03K17/6874
摘要： A driving circuit for an N-channel Metal Oxide Semiconductor (NMOS) transistor can include a charge pump unit and a driver coupled to the charge pump. The charge pump can receive a source voltage and output an output voltage higher than the source voltage, where the source voltage is applied to a source terminal of the NMOS transistor. The driver receives the output voltage of the charge pump unit and converts the output voltage to a driving voltage operable for conducting the NMOS transistor.
摘要翻译： 用于N沟道金属氧化物半导体（NMOS）晶体管的驱动电路可以包括电荷泵单元和耦合到电荷泵的驱动器。 电荷泵可以接收源电压并输出高于源极电压的输出电压，其中源极电压施加到NMOS晶体管的源极端子。 驱动器接收电荷泵单元的输出电压，并将输出电压转换成可操作用于导通NMOS晶体管的驱动电压。
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公开(公告)号：US20080304293A1
公开(公告)日：2008-12-11
申请号：US11810472
申请日：2007-06-05
CPC分类号： H02M3/335 , H02M2001/0006
摘要： A converter controller is disclosed. In one embodiment, a controller for a flyback converter includes a converter and a flyback controller. The converter is coupled to the flyback converter for receiving an auxiliary voltage and for generating a constant power voltage. The flyback controller is powered by the constant power voltage for controlling an output voltage of the flyback converter. Furthermore, the flyback converter comprises a transformer with a primary side and a secondary side. The output voltage and the auxiliary voltage are produced at the transformer.
摘要翻译： 公开了一种转换器控制器。 在一个实施例中，用于反激式转换器的控制器包括转换器和回扫控制器。 转换器耦合到反激转换器，用于接收辅助电压并产生恒定功率电压。 反激控制器由用于控制反激式转换器的输出电压的恒定电源电压供电。 此外，反激式转换器包括具有初级侧和次级侧的变压器。 变压器产生输出电压和辅助电压。
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