专利检索 ap:("Alexander Heim-Riether" OR "Anil Kumar Padyana" OR "Shuang Liang" OR "Steven John Taylor" OR "Qiang Zhang") AND inv:"Anil Kumar Padyana" 第 1 页

1.

发明授权
Arylpyrazole ethers as inhibitors of leukotriene A4 hydrolase 有权
标题翻译：芳基吡唑醚作为白三烯A4水解酶的抑制剂

公开(公告)号：US09139567B2

公开(公告)日：2015-09-22

申请号：US14233520

申请日：2012-07-17

申请人： Alexander Heim-Riether , Anil Kumar Padyana , Shuang Liang , Steven John Taylor , Qiang Zhang

发明人： Alexander Heim-Riether , Anil Kumar Padyana , Shuang Liang , Steven John Taylor , Qiang Zhang

IPC分类号： C07D403/12 , C07D401/14 , C07D405/14 , C07D413/14 , C07D231/12 , C07D401/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D417/12 , C07D471/04 , C07D513/04

CPC分类号： C07D403/12 , C07D231/12 , C07D401/12 , C07D401/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/04 , C07D513/04

摘要： The present invention relates to compounds of formula I or a pharmaceutically acceptable salt thereof, wherein A1, A2, A3, L1, L2 and D are as defined herein. The compounds of formula (I) are useful as inhibitors of leukotriene A4 hydrolase (LTA4H) and treating LTA4H related disorder. The present invention also relates to pharmaceutical compositions comprising the Compounds of formula (I), methods of using these compounds in the treatment of various diseases and disorders, and processes for preparing these compounds.

摘要翻译： 本发明涉及式I化合物或其药学上可接受的盐，其中A1，A2，A3，L1，L2和D如本文所定义。式（I）化合物可用作白三烯A4水解酶（LTA4H）的抑制剂和治疗LTA4H相关病症。本发明还涉及包含式（I）化合物的药物组合物，使用这些化合物治疗各种疾病和病症的方法，以及制备这些化合物的方法。

2.

发明申请
ARYLPYRAZOLE ETHERS AS INHIBITORS OF LEUKOTRIENE A4 HYDROLASE 有权
标题翻译： ARYLPYRAZOLE ETHERS作为LEUKOTRIENE A4水解酶的抑制剂

公开(公告)号：US20140221373A1

公开(公告)日：2014-08-07

申请号：US14233520

申请日：2012-07-17

申请人： Alexander Heim-Riether , Anil Kumar Padyana , Shuang Liang , Steven John Taylor , Qiang Zhang

发明人： Alexander Heim-Riether , Anil Kumar Padyana , Shuang Liang , Steven John Taylor , Qiang Zhang

IPC分类号： C07D403/12 , C07D401/14 , C07D471/04 , C07D413/12 , C07D405/12 , C07D513/04 , C07D413/14 , C07D401/12

CPC分类号： C07D403/12 , C07D231/12 , C07D401/12 , C07D401/14 , C07D405/12 , C07D405/14 , C07D409/12 , C07D413/12 , C07D413/14 , C07D417/12 , C07D471/04 , C07D513/04

摘要： The present invention relates to compounds of formula I or a pharmaceutically acceptable salt thereof, wherein A1, A2, A3, L1, L2 and D are as defined herein. The compounds of formula (I) are useful as inhibitors of leukotriene A4 hydrolase (LTA4H) and treating LTA4H related disorder. The present invention also relates to pharmaceutical compositions comprising the Compounds of formula (I), methods of using these compounds in the treatment of various diseases and disorders, and processes for preparing these compounds.

摘要翻译： 本发明涉及式I化合物或其药学上可接受的盐，其中A1，A2，A3，L1，L2和D如本文所定义。式（I）化合物可用作白三烯A4水解酶（LTA4H）的抑制剂和治疗LTA4H相关病症。本发明还涉及包含式（I）化合物的药物组合物，使用这些化合物治疗各种疾病和病症的方法，以及制备这些化合物的方法。