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    LIFT CHAIR
    1.
    发明申请
    LIFT CHAIR 审中-公开
    吊椅

    公开(公告)号：US20170007479A1

    公开(公告)日：2017-01-12

    申请号：US15206727

    申请日：2016-07-11

    申请人： Amy Armenta ,  Kenneth Bradley ,  Alex Brown ,  Daisy Mezano Fuentes ,  Arynn Jawaughn Howell ,  Nathan Pratt

    发明人： Amy Armenta ,  Kenneth Bradley ,  Alex Brown ,  Daisy Mezano Fuentes ,  Arynn Jawaughn Howell ,  Nathan Pratt

    IPC分类号： A61G5/14 ,  A47C7/00

    CPC分类号： A61G5/14

    摘要： The presently disclosed inventive concepts relate generally to lift chairs, such as a lift chair comprising a frame having a back portion and a front portion defining an interior space, and a first horizontal member positioned between the back portion and the front portion; a foot platform positioned at least partially in the interior space of the frame, the foot platform having a lowered position and a raised position; a seat positioned at least partially in the interior space of the frame and above the platform and pivotally connected to the first horizontal member, the seat having a first end portion and a second end portion, and pivotable between a standing position and a seated position; and a motion translation system configured such that pivoting the seat between the standing position and the seated position moves the platform vertically between the lowered position and the raised position.

    摘要翻译： 目前公开的发明构思一般涉及升降椅，例如升降椅，其包括具有后部的框架和限定内部空间的前部，以及位于后部和前部之间的第一水平构件; 至少部分地位于所述框架的内部空间中的脚踏台，所述脚踏台具有降低的位置和升高位置; 至少部分地位于所述框架的内部空间中并位于所述平台之上并且枢转地连接到所述第一水平构件的座椅，所述座具有第一端部部分和第二端部部分，并且可在竖立位置和就座位置之间枢转; 以及运动平移系统，其构造成使得所述座椅在所述直立位置和所述就座位置之间枢转使所述平台在所述降低位置和所述升高位置之间垂直移动。

    Surface Mapping by Optical Manipulation of Particles in Relation to a Functionalized Surface
    2.
    发明申请
    Surface Mapping by Optical Manipulation of Particles in Relation to a Functionalized Surface 有权
    通过光学操作颗粒与功能化表面的表面贴图

    公开(公告)号：US20110026009A1

    公开(公告)日：2011-02-03

    申请号：US12440949

    申请日：2007-09-14

    申请人： Christopher Knutson ,  Crystal Duke ,  Gary Stacey ,  Dan Mueth ,  Evan Tanner ,  Osman Akcakir ,  Haojun Fu ,  Robert Lancelot ,  Tania Chakrabarty ,  Kenneth Bradley

    发明人： Christopher Knutson ,  Crystal Duke ,  Gary Stacey ,  Dan Mueth ,  Evan Tanner ,  Osman Akcakir ,  Haojun Fu ,  Robert Lancelot ,  Tania Chakrabarty ,  Kenneth Bradley

    IPC分类号： G01N33/48 ,  G01B11/30

    CPC分类号： G01N33/48 ,  G01N33/54373 ,  G01N33/80

    摘要： Methods and apparatus for analyzing surface properties of particles are provided. A method for analyzing the surface properties of the particle includes a associating a first particle with a first capture zone having a specific binding affinity for a first chemical species, applying an optical force to the first particle, sensing a response of the first particle to the optical force, and using the sensed response to determine the presence, absence or quantity of the first chemical species on the first particle surface. This process may be repeated in parallel to test multiple particles. In addition to directly testing the surface properties of the particles, the method can be used in direct, indirect and competitive assays to determine the presence, absence or quantity of free or immobilized analytes. A fluidic cartridge with capture zones having avidities that are tuned for the use of optical forces is provided. A software routine for performing the method is also provided.

    摘要翻译： 提供了分析颗粒表面性质的方法和装置。 用于分析颗粒的表面性质的方法包括将第一颗粒与对第一化学物质具有特异性结合亲和力的第一捕获区缔合，向第一颗粒施加光学力，感测第一颗粒对第一颗粒的响应 并且使用感测到的响应来确定第一颗粒表面上的第一化学物质的存在，不存在或数量。 该过程可以并行重复以测试多个颗粒。 除了直接测试颗粒的表面性质之外，该方法可用于直接，间接和竞争性测定，以确定游离或固定化分析物的存在，不存在或数量。 提供了一种具有捕获区域的流体盒，其具有被调整以用于光学力的空间。 还提供了用于执行该方法的软件程序。

    System and method for manipulating and processing materials using holographic optical trapping
    5.
    发明申请
    System and method for manipulating and processing materials using holographic optical trapping 审中-公开
    使用全息光学捕获来操纵和处理材料的系统和方法

    公开(公告)号：US20090002790A1

    公开(公告)日：2009-01-01

    申请号：US12230430

    申请日：2008-08-28

    申请人： Joseph Plewa ,  Evan Tanner ,  Dan Mueth ,  Lewis Gruber ,  Kenneth Bradley

    发明人： Joseph Plewa ,  Evan Tanner ,  Dan Mueth ,  Lewis Gruber ,  Kenneth Bradley

    IPC分类号： G03H1/04 ,  G02F1/29 ,  G02B27/40

    CPC分类号： B82Y10/00 ,  G03H1/08 ,  G03H1/2294 ,  G03H2001/0077 ,  G03H2225/32

    摘要： An apparatus for manipulating particles (micro, nano, and pico) having one or more characteristics with an optical trap formed by modulating a laser beam with a Diffractive Optical Element (DOE). At least one characteristic of the material is selected; and a laser beam having a selected wavelength corresponding to the at least one selected characteristic of the material is generated. Values of the DOE are calculated corresponding to the at least one selected characteristic of the material. The beam and the DOE are modulated to produce a holographic optical trap having properties corresponding to the at least one selected characteristic; the trap is focused to a beam focus or selected spot size; and the beam focus is located near a particle location for trapping the particle therein.

    摘要翻译： 一种用于通过用衍射光学元件（DOE）调制激光束而形成的光阱来操纵具有一个或多个特性的微粒（微，纳米和微微）的装置。 选择材料的至少一种特性; 并且产生具有与材料的至少一个所选特征对应的选定波长的激光束。 根据材料的至少一个所选特征计算DOE的值。 光束和DOE被调制以产生具有对应于至少一个所选特征的性质的全息光阱; 陷阱聚焦到光束焦点或选定的光斑尺寸; 并且束聚焦位于颗粒位置附近以将颗粒捕获在其中。

    Optical switches and routers and optical filters
    7.
    发明授权
    Optical switches and routers and optical filters 失效
    光开关和路由器和光滤波器

    公开(公告)号：US07466883B2

    公开(公告)日：2008-12-16

    申请号：US11403941

    申请日：2006-04-14

    申请人： Kenneth Bradley ,  Ward Lopes

    发明人： Kenneth Bradley ,  Ward Lopes

    IPC分类号： G02B6/26 ,  G02B6/32

    CPC分类号： G02B6/12007 ,  G02B6/29341 ,  G02B6/29343 ,  G02F1/3132 ,  G02F2203/15

    摘要： Our invention relates generally to an optical switch (31) and an optical router (10) to rapidly route signals from particular channels (22, 24) within an optical band by using optical switches (20) which utilize a controlled whispering gallery mode (WGM) resonance of dielectric microspheres (S1, S2, S3) to optically switch signals. Another invention relates to optical filters which use a WGM resonate structure (150) to isolate and switch specific optical signals between waveguides (F1, F2). In other inventions, the filter (100) is switched “on/off” by signal loss within a WGM resonate structure (150) which disrupts the WGM resonance; the filter (100) isolates and switches a specific wavelength signal from among a group of signals of different wavelengths; and is switched “off” by adjusting the index of refraction of the resonate structure to become substantially similar to the index of refraction of the surrounding medium.

    摘要翻译： 本发明一般涉及光开关（31）和光路由器（10），用于通过使用光开关（20）来快速地从光频带内的特定通道（22,24）传送信号，所述光开关利用受控的耳语画廊模式（WGM ）电介质微球的共振（S1，S2，S3）来光学切换信号。 另一发明涉及使用WGM谐振结构（150）来隔离和切换波导（F1，F2）之间的特定光信号的滤光器。 在其它发明中，滤波器（100）通过在WGM共振结构（150）内的信号损失被切换为“开/关”，这破坏了WGM谐振; 滤波器（100）从不同波长的一组信号中隔离并切换特定的波长信号; 并且通过调节谐振结构的折射率而变得基本上类似于周围介质的折射率而被切换为“关闭”。

    System and method for manipulating and processing materials using holographic optical trapping
    8.
    发明授权
    System and method for manipulating and processing materials using holographic optical trapping 失效
    使用全息光学捕获来操纵和处理材料的系统和方法

    公开(公告)号：US07449679B2

    公开(公告)日：2008-11-11

    申请号：US11079533

    申请日：2005-03-15

    申请人： Joseph Plewa ,  Evan Tanner ,  Daniel Mueth ,  Lewis Gruber ,  Kenneth Bradley

    发明人： Joseph Plewa ,  Evan Tanner ,  Daniel Mueth ,  Lewis Gruber ,  Kenneth Bradley

    IPC分类号： H05H3/02 ,  C12N13/00

    CPC分类号： B82Y20/00 ,  B82Y10/00 ,  G03H1/08 ,  G03H1/2294 ,  G03H2001/0077 ,  G03H2225/32

    摘要： A method and apparatus for manipulating particles (micro, nano, and pico) having one or more characteristics with an optical trap formed by modulating a laser beam with a Diffractive Optical Element (DOE). At least one characteristic of the material is selected; and a laser beam having a selected wavelength corresponding to the at least one selected characteristic of the material is generated. Values of the DOE are calculated corresponding to the at least one selected characteristic of the material. The beam and the DOE are modulated to produce a holographic optical trap having properties corresponding to the at least one selected characteristic; the trap is focused to a beam focus or selected spot size; and the beam focus is located near a particle location for trapping the particle therein.

    摘要翻译： 一种用于通过用衍射光学元件（DOE）调制激光束而形成的光阱来操纵具有一个或多个特性的微粒（微，纳米和微微）的方法和装置。 选择材料的至少一种特性; 并且产生具有与材料的至少一个所选特征对应的选定波长的激光束。 根据材料的至少一个所选特征计算DOE的值。 光束和DOE被调制以产生具有对应于至少一个所选特征的性质的全息光阱; 陷阱聚焦到光束焦点或选定的光斑尺寸; 并且束聚焦位于颗粒位置附近以将颗粒捕获在其中。

    Optical switches and routers and optical filters
    9.
    发明申请
    Optical switches and routers and optical filters 失效
    光开关和路由器和光滤波器

    公开(公告)号：US20060193557A1

    公开(公告)日：2006-08-31

    申请号：US11403941

    申请日：2006-04-14

    申请人： Kenneth Bradley ,  Ward Lopes

    发明人： Kenneth Bradley ,  Ward Lopes

    IPC分类号： G02B6/26 ,  G02B6/42

    CPC分类号： G02B6/12007 ,  G02B6/29341 ,  G02B6/29343 ,  G02F1/3132 ,  G02F2203/15

    摘要： Our invention relates generally to an optical switch (31) and an optical router (10) to rapidly route signals from particular channels (22, 24) within an optical band by using optical switches (20) which utilize a controlled whispering gallery mode (WGM) resonance of dielectric microspheres (S1, S2, S3) to optically switch signals. Another invention relates to optical filters which use a WGM resonate structure (150) to isolate and switch specific optical signals between waveguides (F1, F2). In other inventions, the filter (100) is switched “on/off” by signal loss within a WGM resonate structure (150) which disrupts the WGM resonance; the filter (100) isolates and switches a specific wavelength signal from among a group of signals of different wavelengths; and is switched “off” by adjusting the index of refraction of the resonate structure to become substantially similar to the index of refraction of the surrounding medium.

    摘要翻译： 本发明一般涉及光开关（31）和光路由器（10），用于通过使用光开关（20）来快速地从光频带内的特定通道（22,24）传送信号，所述光开关利用受控的耳语画廊模式（WGM ）电介质微球的共振（S 1，S 2，S 3）来光学切换信号。 另一个发明涉及使用WGM谐振结构（150）来隔离和切换波导（F 1，F 2）之间的特定光信号的滤光器。 在其它发明中，滤波器（100）通过在WGM共振结构（150）内的信号损失被切换为“开/关”，这破坏了WGM谐振; 滤波器（100）从不同波长的一组信号中隔离并切换特定的波长信号; 并且通过调节谐振结构的折射率而变得基本上类似于周围介质的折射率而被切换为“关闭”。

    RECEPTOR FOR B. ANTHRACIS TOXIN
    10.
    发明申请
    RECEPTOR FOR B. ANTHRACIS TOXIN 有权
    受体拮抗剂

    公开(公告)号：US20060110801A1

    公开(公告)日：2006-05-25

    申请号：US09970076

    申请日：2001-10-03

    申请人： John Young ,  Kenneth Bradley ,  R. Collier ,  Jeremy Mogridge

    发明人： John Young ,  Kenneth Bradley ,  R. Collier ,  Jeremy Mogridge

    IPC分类号： C07H21/04 ,  C12N15/74 ,  C12N1/21 ,  C07K14/32 ,  C07K14/705

    CPC分类号： C07K14/705 ,  A61K38/00

    摘要： The present invention relates to mammalian anthrax toxin receptor polypeptides and polynucleotides encoding same as well as related polypeptides and polynucleotides, vectors containing the polynucleotides and polypeptides, host cells containing related polynucleotide molecules, and cells displaying no anthrax toxin receptor on an exterior surface of the cells-minus cell lines and animals. The present invention also relates to methods for identifying molecules that bind the anthrax toxin receptor and molecules that reduce the toxicity of anthrax toxin. Finally, the present invention provides methods for treating human and non-human animals suffering from anthrax.

    摘要翻译： 本发明涉及哺乳动物炭疽毒素受体多肽和编码其的多核苷酸以及相关多肽和多核苷酸，含有多核苷酸和多肽的载体，含有相关多核苷酸分子的宿主细胞和在细胞外表面上不显示炭疽毒素受体的细胞 - 细胞系和动物。 本发明还涉及用于鉴定结合炭疽毒素受体的分子和降低炭疽毒素毒性的分子的方法。 最后，本发明提供了治疗患有炭疽的人类和非人类动物的方法。