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公开(公告)号:US07993894B2
公开(公告)日:2011-08-09
申请号:US12354255
申请日:2009-01-15
申请人: Andrew P. Kloek , Deryck J. Williams , Merry B. McLaird , John D. Bradley , Jennifer A. DaVila-Aponte , Siqun Xu , Anita M. Frevert
发明人: Andrew P. Kloek , Deryck J. Williams , Merry B. McLaird , John D. Bradley , Jennifer A. DaVila-Aponte , Siqun Xu , Anita M. Frevert
IPC分类号: C12N9/02 , C12N1/20 , C12N15/00 , C12N9/00 , C12P21/04 , C12Q1/68 , C12Q1/48 , C12Q1/00 , C07H21/04
CPC分类号: C12N9/0083 , C12N15/8247 , C12N15/8285 , G01N33/573 , G01N2333/4353 , Y02A40/164
摘要: Nucleic acid molecules from nematodes encoding fatty acid desaturase polypeptides are described. Fatty acid desaturase-like polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of fatty acid desaturase-like nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators of fatty acid desaturase-like polypeptides, as well as methods for antibody production.
摘要翻译: 描述了编码脂肪酸去饱和酶多肽的线虫的核酸分子。 还提供了脂肪酸去饱和酶样多肽序列,以及用于产生脂肪酸去饱和酶样核苷酸和多肽的载体,宿主细胞和重组方法。 还描述了用于鉴定脂肪酸去饱和酶样多肽的抑制剂和/或激活剂的筛选方法以及用于抗体生产的方法。
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公开(公告)号:US20100248357A1
公开(公告)日:2010-09-30
申请号:US12354255
申请日:2009-01-15
申请人: Andrew P. Kloek , Deryck J. Williams , Merry B. McLaird , John D. Bradley , Jennifer A. DaVila-Aponte , Siqun Xu , Anita M. Frevert
发明人: Andrew P. Kloek , Deryck J. Williams , Merry B. McLaird , John D. Bradley , Jennifer A. DaVila-Aponte , Siqun Xu , Anita M. Frevert
CPC分类号: C12N9/0083 , C12N15/8247 , C12N15/8285 , G01N33/573 , G01N2333/4353 , Y02A40/164
摘要: Nucleic acid molecules from nematodes encoding fatty acid desaturase polypeptides are described. Fatty acid desaturase-like polypeptide sequences are also provided, as are vectors, host cells, and recombinant methods for production of fatty acid desaturase-like nucleotides and polypeptides. Also described are screening methods for identifying inhibitors and/or activators of fatty acid desaturase-like polypeptides, as well as methods for antibody production.
摘要翻译: 描述了编码脂肪酸去饱和酶多肽的线虫的核酸分子。 还提供了脂肪酸去饱和酶样多肽序列,以及用于产生脂肪酸去饱和酶样核苷酸和多肽的载体,宿主细胞和重组方法。 还描述了用于鉴定脂肪酸去饱和酶样多肽的抑制剂和/或激活剂的筛选方法以及用于抗体生产的方法。
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