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公开(公告)号：US08574884B2
公开(公告)日：2013-11-05
申请号：US13345547
申请日：2012-01-06
申请人： Andrew Shaw , Louise Wallace , David A. Estell , Ronaldus W. J. Hommes , Sang-Kyu Lee , Hiroshi Oh , Eugene S. Sadlowski
发明人： Andrew Shaw , Louise Wallace , David A. Estell , Ronaldus W. J. Hommes , Sang-Kyu Lee , Hiroshi Oh , Eugene S. Sadlowski
IPC分类号： C12N9/54 , C12N9/50 , C12N1/20 , C12N15/00 , C12P21/06 , D06M16/00 , C02F3/34 , C14C1/00 , C12P1/00 , C07H21/04 , C11D3/00 , C07K1/00
CPC分类号： C12N9/54 , C11D1/02 , C11D3/386 , C11D3/38663 , C12Y304/24
摘要： The present invention provides methods and compositions comprising at least one neutral metalloprotease enzyme that has improved storage stability. In some embodiments, the neutral metalloprotease finds use in cleaning and other applications. In some particularly preferred embodiments, the present invention provides methods and compositions comprising neutral metalloprotease(s) obtained from Bacillus sp. In some more particularly preferred embodiments, the neutral metalloprotease is obtained from B. amyloliquefaciens. In still further preferred embodiments, the neutral metalloprotease is a variant of the B. amyloliquefaciens neutral metalloprotease. In yet additional embodiments, the neutral metalloprotease is a homolog of the B. amyloliquefaciens neutral metalloprotease. The present invention finds particular use in applications including, but not limited to cleaning, bleaching and disinfecting.
摘要翻译： 本发明提供包含至少一种具有改善的储存稳定性的中性金属蛋白酶的方法和组合物。 在一些实施方案中，中性金属蛋白酶可用于清洁和其它应用。 在一些特别优选的实施方案中，本发明提供了包含从芽孢杆菌属芽孢杆菌获得的中性金属蛋白酶的方法和组合物。 在一些更特别优选的实施方案中，中性金属蛋白酶从解淀粉芽孢杆菌获得。 在另外的优选实施方案中，中性金属蛋白酶是解淀粉芽孢杆菌中性金属蛋白酶的变体。 在另外的实施方案中，中性金属蛋白酶是解淀粉芽孢杆菌中性金属蛋白酶的同系物。 本发明特别用于包括但不限于清洁，漂白和消毒的应用。
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公开(公告)号：US20090263882A1
公开(公告)日：2009-10-22
申请号：US12473735
申请日：2009-05-28
申请人： Andrew Shaw , Louise Wallace , David A. Estell , Ronaldus W. J, Hommes , Sang-Kyu Lee , Hiroshi Oh , Eugene S. Sadlowski
发明人： Andrew Shaw , Louise Wallace , David A. Estell , Ronaldus W. J, Hommes , Sang-Kyu Lee , Hiroshi Oh , Eugene S. Sadlowski
IPC分类号： C12N9/50
CPC分类号： C12N9/54 , C11D1/02 , C11D3/386 , C11D3/38663 , C12Y304/24
摘要： The present invention provides methods and compositions comprising at least one neutral metalloprotease enzyme that has improved storage stability. In some embodiments, the neutral metalloprotease finds use in cleaning and other applications. In some particularly preferred embodiments, the present invention provides methods and compositions comprising neutral metalloprotease(s) obtained from Bacillus sp. In some more particularly preferred embodiments, the neutral metalloprotease is obtained from B. amyloliquefaciens. In still further preferred embodiments, the neutral metalloprotease is a variant of the B. amyloliquefaciens neutral metalloprotease. In yet additional embodiments, the neutral metalloprotease is a homolog of the B. amyloliquefaciens neutral metalloprotease. The present invention finds particular use in applications including, but not limited to cleaning, bleaching and disinfecting.
摘要翻译： 本发明提供包含至少一种具有改善的储存稳定性的中性金属蛋白酶的方法和组合物。 在一些实施方案中，中性金属蛋白酶可用于清洁和其它应用。 在一些特别优选的实施方案中，本发明提供了包含从芽孢杆菌属芽孢杆菌获得的中性金属蛋白酶的方法和组合物。 在一些更特别优选的实施方案中，中性金属蛋白酶从解淀粉芽孢杆菌获得。 在另外的优选实施方案中，中性金属蛋白酶是解淀粉芽孢杆菌中性金属蛋白酶的变体。 在另外的实施方案中，中性金属蛋白酶是解淀粉芽孢杆菌中性金属蛋白酶的同系物。 本发明特别用于包括但不限于清洁，漂白和消毒的应用。
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公开(公告)号：US08114656B2
公开(公告)日：2012-02-14
申请号：US12473735
申请日：2009-05-28
申请人： Andrew Shaw , Louise Wallace , David A. Estell , Ronaldus W. J. Hommes , Sang-Kyu Lee , Hiroshi Oh , Eugene S. Sadlowski
发明人： Andrew Shaw , Louise Wallace , David A. Estell , Ronaldus W. J. Hommes , Sang-Kyu Lee , Hiroshi Oh , Eugene S. Sadlowski
CPC分类号： C12N9/54 , C11D1/02 , C11D3/386 , C11D3/38663 , C12Y304/24
摘要： The present invention provides methods and compositions comprising at least one neutral metalloprotease enzyme that has improved storage stability. In some embodiments, the neutral metalloprotease finds use in cleaning and other applications. In some particularly preferred embodiments, the present invention provides methods and compositions comprising neutral metalloprotease(s) obtained from Bacillus sp. In some more particularly preferred embodiments, the neutral metalloprotease is obtained from B. amyloliquefaciens. In still further preferred embodiments, the neutral metalloprotease is a variant of the B. amyloliquefaciens neutral metalloprotease. In yet additional embodiments, the neutral metalloprotease is a homolog of the B. amyloliquefaciens neutral metalloprotease. The present invention finds particular use in applications including, but not limited to cleaning, bleaching and disinfecting.
摘要翻译： 本发明提供包含至少一种具有改善的储存稳定性的中性金属蛋白酶的方法和组合物。 在一些实施方案中，中性金属蛋白酶可用于清洁和其它应用。 在一些特别优选的实施方案中，本发明提供了包含从芽孢杆菌属芽孢杆菌获得的中性金属蛋白酶的方法和组合物。 在一些更特别优选的实施方案中，中性金属蛋白酶从解淀粉芽孢杆菌获得。 在另外的优选实施方案中，中性金属蛋白酶是解淀粉芽孢杆菌中性金属蛋白酶的变体。 在另外的实施方案中，中性金属蛋白酶是解淀粉芽孢杆菌中性金属蛋白酶的同系物。 本发明特别用于包括但不限于清洁，漂白和消毒的应用。
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公开(公告)号：US20120107907A1
公开(公告)日：2012-05-03
申请号：US13345547
申请日：2012-01-06
申请人： Andrew Shaw , Louise Wallace , David A. Estell , Ronald W. J. Hommes , Sang-Kyu Lee , Hiroshi Oh , Eugene S. Sadlowski
发明人： Andrew Shaw , Louise Wallace , David A. Estell , Ronald W. J. Hommes , Sang-Kyu Lee , Hiroshi Oh , Eugene S. Sadlowski
CPC分类号： C12N9/54 , C11D1/02 , C11D3/386 , C11D3/38663 , C12Y304/24
摘要： The present invention provides methods and compositions comprising at least one neutral metalloprotease enzyme that has improved storage stability. In some embodiments, the neutral metalloprotease finds use in cleaning and other applications. In some particularly preferred embodiments, the present invention provides methods and compositions comprising neutral metalloprotease(s) obtained from Bacillus sp. In some more particularly preferred embodiments, the neutral metalloprotease is obtained from B. amyloliquefaciens. In still further preferred embodiments, the neutral metalloprotease is a variant of the B. amyloliquefaciens neutral metalloprotease. In yet additional embodiments, the neutral metalloprotease is a homolog of the B. amyloliquefaciens neutral metalloprotease. The present invention finds particular use in applications including, but not limited to cleaning, bleaching and disinfecting.
摘要翻译： 本发明提供包含至少一种具有改善的储存稳定性的中性金属蛋白酶的方法和组合物。 在一些实施方案中，中性金属蛋白酶可用于清洁和其它应用。 在一些特别优选的实施方案中，本发明提供了包含从芽孢杆菌属芽孢杆菌获得的中性金属蛋白酶的方法和组合物。 在一些更特别优选的实施方案中，中性金属蛋白酶从解淀粉芽孢杆菌获得。 在另外的优选实施方案中，中性金属蛋白酶是解淀粉芽孢杆菌中性金属蛋白酶的变体。 在另外的实施方案中，中性金属蛋白酶是解淀粉芽孢杆菌中性金属蛋白酶的同系物。 本发明特别用于包括但不限于清洁，漂白和消毒的应用。
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公开(公告)号：US20080293610A1
公开(公告)日：2008-11-27
申请号：US11581102
申请日：2006-10-12
申请人： Andrew Shaw , Louise Wallace , David A. Estell , Ronaldus W.J. Hommes , Sang-Kyu Lee , Hiroshi Oh , Eugene S. Sadlowski
发明人： Andrew Shaw , Louise Wallace , David A. Estell , Ronaldus W.J. Hommes , Sang-Kyu Lee , Hiroshi Oh , Eugene S. Sadlowski
IPC分类号： C11D7/42 , C12N9/54 , C07H21/00 , C12N15/63 , C12S9/00 , C12S11/00 , C12N1/21 , C07K14/00 , C12N15/00
CPC分类号： C12N9/54 , C11D1/02 , C11D3/386 , C11D3/38663 , C12Y304/24
摘要： The present invention provides methods and compositions comprising at least one neutral metalloprotease enzyme that has improved storage stability. In some embodiments, the neutral metalloprotease finds use in cleaning and other applications. In some particularly preferred embodiments, the present invention provides methods and compositions comprising neutral metalloprotease(s) obtained from Bacillus sp. In some more particularly preferred embodiments, the neutral metalloprotease is obtained from B. amyloliquefaciens. In still further preferred embodiments, the neutral metalloprotease is a variant of the B. amyloliquefaciens neutral metalloprotease. In yet additional embodiments, the neutral metalloprotease is a homolog of the B. amyloliquefaciens neutral metalloprotease. The present invention finds particular use in applications including, but not limited to cleaning, bleaching and disinfecting.
摘要翻译： 本发明提供包含至少一种具有改善的储存稳定性的中性金属蛋白酶的方法和组合物。 在一些实施方案中，中性金属蛋白酶可用于清洁和其它应用。 在一些特别优选的实施方案中，本发明提供了包含从芽孢杆菌属芽孢杆菌获得的中性金属蛋白酶的方法和组合物。 在一些更特别优选的实施方案中，中性金属蛋白酶从解淀粉芽孢杆菌获得。 在另外的优选实施方案中，中性金属蛋白酶是解淀粉芽孢杆菌中性金属蛋白酶的变体。 在另外的实施方案中，中性金属蛋白酶是解淀粉芽孢杆菌中性金属蛋白酶的同系物。 本发明特别用于包括但不限于清洁，漂白和消毒的应用。
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公开(公告)号：US08535927B1
公开(公告)日：2013-09-17
申请号：US10576331
申请日：2004-11-19
申请人： Brian E. Jones , Marc Kolkman , Chris Leeflang , Hiroshi Oh , Ayrookaran J. Poulose , Eugene S. Sadlowski , Andrew Shaw , Leo van Marrewijk , Wilhelmus A. H. Van Der Kleij
发明人： Brian E. Jones , Marc Kolkman , Chris Leeflang , Hiroshi Oh , Ayrookaran J. Poulose , Eugene S. Sadlowski , Andrew Shaw , Leo van Marrewijk , Wilhelmus A. H. Van Der Kleij
CPC分类号： C12N9/52 , C07K2299/00 , C11D3/386
摘要： The present invention provides novel serine proteases, novel genetic material encoding these enzymes, and proteolytic proteins obtained from Micrococcineae spp., including but not limited to Cellulomonas spp. and variant proteins developed therefrom. In particular, the present invention provides protease compositions obtained from a Cellulomonas spp, DNA encoding the protease, vectors comprising the DNA encoding the protease, host cells transformed with the vector DNA, and an enzyme produced by the host cells. The present invention also provides cleaning compositions (e.g., detergent compositions), animal feed compositions, and textile and leather processing compositions comprising protease(s) obtained from a Micrococcineae spp., including but not limited to Cellulomonas spp. In alternative embodiments, the present invention provides mutant (i.e., variant) proteases derived from the wild-type proteases described herein. These mutant proteases also find use in numerous applications.
摘要翻译： 本发明提供了新的丝氨酸蛋白酶，编码这些酶的新型遗传物质，以及从微球菌属（Micrococcineae spp。）获得的蛋白水解蛋白，包括但不限于纤维单胞菌属（Cellulomonas spp） 和从其开发的变体蛋白质。 特别地，本发明提供了从纤维单胞菌属（Splulomonas spp）获得的蛋白酶组合物，编码蛋白酶的DNA，包含编码蛋白酶的载体的载体，用载体DNA转化的宿主细胞和由宿主细胞产生的酶。 本发明还提供了清洁组合物（例如洗涤剂组合物），动物饲料组合物，以及包含从微球菌（Micrococcineae spp。）获得的蛋白酶的纺织和皮革加工组合物，其包括但不限于纤维单胞菌属（Cellulomonas spp） 在替代实施方案中，本发明提供衍生自本文所述的野生型蛋白酶的突变体（即，变体）蛋白酶。 这些突变型蛋白酶也可用于许多应用。
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公开(公告)号：US5055218A
公开(公告)日：1991-10-08
申请号：US508994
申请日：1990-04-13
CPC分类号： C11D3/3945
摘要： This is a bleach granule comprising the nonylamide of peroxyadipic acid with a average particle size of about 0.1 to 260 microns, bleach-stable surfactant, and a hydratable, NAPAA-compatible material, e.g. sodium sulfate. The bleach granules are stable and are effective bleaching agents.
摘要翻译： 这是一种漂白颗粒，其包含平均粒度为约0.1至260微米的过氧己二酸的壬酰胺，漂白稳定的表面活性剂和可水合的NAPAA相容的材料，例如。 硫酸钠。 漂白颗粒是稳定的并且是有效的漂白剂。
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8.发明授权Particles containing ammonium salts or other chlorine scavengers for detergent compositions 失效含有洗涤剂组合物的铵盐或其它氯清除剂的颗粒
公开(公告)号：US4810413A
公开(公告)日：1989-03-07
申请号：US055815
申请日：1987-05-29
CPC分类号： C11D3/046 , C11D3/0042 , C11D3/38609
摘要： Granular detergent compositions contain a low level of ammonium salt or salt of specific anion chlorine scavenger which is preferably protected in a particle. Such salts protect enzymes in the wash process. The preferred particles can also comprise, e.g., a suds-controlling silicone material which is substantially removed from contact with the surfactant component or alkaline component of the composition. The particles preferably use, e.g., a polyethylene glycol carrier, with preferably a small amount of fatty acid, in an irregularly shaped particle having a minimum dimension of at least about 0.05 cm.
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9.发明授权Liquid or granular automatic dishwashing detergent compositions containing silicate and low molecular weight modified polyacrylate coploymers 失效含有硅酸盐和低分子量改性聚丙烯酸酯共聚合物的液体或颗粒自动餐具洗涤剂组合物
公开(公告)号：US5597789A
公开(公告)日：1997-01-28
申请号：US469740
申请日：1995-06-06
申请人： Eugene S. Sadlowski
发明人： Eugene S. Sadlowski
IPC分类号： C11D3/06 , C11D3/08 , C11D3/20 , C11D3/36 , C11D3/37 , C11D3/386 , C11D17/00 , C11D7/14 , C11D7/36
CPC分类号： C11D3/06 , C11D17/003 , C11D3/08 , C11D3/2086 , C11D3/361 , C11D3/3757 , C11D3/386 , C11D3/38627
摘要： Liquid or granular automatic dishwashing detergent compositions comprising silicate and low molecular weight polyacrylate copolymer exhibiting enhanced hard water filming performance.
摘要翻译： 包含显示增强的硬水成膜性能的硅酸盐和低分子量聚丙烯酸酯共聚物的液体或颗粒自动餐具洗涤剂组合物。
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10.发明授权Liquid or granular automatic diswashing detergent compositions containing builder, enzyme and low molecular weight, modified polyacrylate copolymers 失效含有助洗剂，酶和低分子量改性聚丙烯酸酯共聚物的液体或颗粒状自动洗涤剂组合物
公开(公告)号：US5591703A
公开(公告)日：1997-01-07
申请号：US441719
申请日：1995-05-15
申请人： Eugene S. Sadlowski
发明人： Eugene S. Sadlowski
CPC分类号： C11D3/08 , C11D3/3757 , C11D3/386
摘要： Liquid or granular automatic dishwashing detergent compositions comprising builder, enzyme and low molecular weight modified polyacrylate copolymers for enhanced hard water filming and enzyme performance.
摘要翻译： 液体或颗粒自动餐具洗涤剂组合物，其包含助洗剂，酶和低分子量改性的聚丙烯酸酯共聚物，用于增强硬水成膜和酶性能。
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