专利检索 ap:("Annie Clauss" OR "Christophe Glaess" OR "Gilbert Marciniak" OR "Nicolas Muzet" OR "Jean-Francois Nave" OR "André Seyer" OR "Bertrand Vivet") AND inv:"Bertrand Vivet" 第 1 页

1.

发明授权
Quinazolinedione derivatives, preparation thereof and therapeutic uses thereof 有权
标题翻译：喹唑啉二酮衍生物，其制备及其治疗用途

公开(公告)号：US08242126B2

公开(公告)日：2012-08-14

申请号：US12754163

申请日：2010-04-05

申请人： Annie Clauss , Christophe Glaess , Gilbert Marciniak , Nicolas Muzet , Jean-Francois Nave , André Seyer , Bertrand Vivet

发明人： Annie Clauss , Christophe Glaess , Gilbert Marciniak , Nicolas Muzet , Jean-Francois Nave , André Seyer , Bertrand Vivet

IPC分类号： A61K31/517

CPC分类号： C07D401/04 , C07D403/04 , C07D471/08

摘要： The invention relates to quinazolinedione derivatives of the general formula (I): wherein A, R1, R2, R3, R4, m, n, p, p′, and r are as defined herein, processes for the preparation thereof and their therapeutic applications.

摘要翻译： 本发明涉及通式（I）的喹唑啉二酮衍生物：其中A，R1，R2，R3，R4，m，n，p，p'和r如本文所定义，其制备方法及其治疗应用。

2.

发明授权
Quinazolinedione derivatives, preparation thereof and various therapeutic uses thereof 有权
标题翻译：喹唑啉二酮衍生物，其制备及其各种治疗用途

公开(公告)号：US08722659B2

公开(公告)日：2014-05-13

申请号：US13268164

申请日：2011-10-07

申请人： Annie Clauss , Christophe Glaess , Gilbert Marciniak , Jean-Francois Nave , Bertrand Vivet

发明人： Annie Clauss , Christophe Glaess , Gilbert Marciniak , Jean-Francois Nave , Bertrand Vivet

IPC分类号： A01N43/00 , A61K31/33 , A01N43/54 , A61K31/517 , A01K31/00

CPC分类号： C07D407/04 , C07D239/96 , C07D309/14 , C07D335/02 , C07D405/04 , C07D405/14 , C07D409/04

摘要： The subject matter of the invention is quinazolinedione derivatives of formula (I), methods for obtaining same and therapeutic uses thereof, such as cancer, diabetes, muscle diseases, bone diseases, cardiovascular diseases, central nervous system diseases, peripheral nervous system diseases, inter alia.

摘要翻译： 本发明的主题是式（I）的喹唑啉酮衍生物，其获得其治疗用途的方法，例如癌症，糖尿病，肌肉疾病，骨病，心血管疾病，中枢神经系统疾病，周围神经系统疾病，特别是

3.

发明申请
NOVEL 1,2,3,4-TETRAHYDRO-PYRIMIDO(1,2-A)PYRIMIDIN-6-ONE DERIVATIVES, PREPARATION THEREOF, AND PHARMACEUTICAL USE THEREOF 有权
标题翻译：新的1,2,3,4-四氢吡喃糖（1,2-A）嘧啶-6-酮衍生物，其制备方法及其药物用途

公开(公告)号：US20120208810A1

公开(公告)日：2012-08-16

申请号：US13381790

申请日：2010-07-01

申请人： Eric Bacque , Maurice Brollo , Annie Clauss , Youssef El Ahmad , Bruno Filoche-Romme , Frank Halley , Karl Andreas Karlsson , Gilbert Marciniak , Baptiste Ronan , Laurent Schio , Bertrand Vivet , Fabrice Viviani , Andre Zimmermann

发明人： Eric Bacque , Maurice Brollo , Annie Clauss , Youssef El Ahmad , Bruno Filoche-Romme , Frank Halley , Karl Andreas Karlsson , Gilbert Marciniak , Baptiste Ronan , Laurent Schio , Bertrand Vivet , Fabrice Viviani , Andre Zimmermann

IPC分类号： A61K31/5377 , A61P35/00 , A61P33/02 , A61P3/00 , A61P33/00 , A61P33/06 , C07D487/04 , A61P35/04

CPC分类号： C07D487/04 , A61K31/519 , A61K31/5377 , C07D239/06 , C07D239/42 , C07D413/14

摘要： The invention relates to the novel materials of formula (I), where: R1 is an optionally substituted L-aryl or L-heteroaryl, such that L is a single bond, alkyl, CO, or CO-alk, or L-X, with L□ being an alkyl and X being O or S; R2 is H or alkyl; R3 is an alkyl optionally substituted by Hal; and R4 is Hou Hal, wherein said materials are in any isomeric form and the salts thereof, to be used as drugs.

摘要翻译： 本发明涉及式（I）的新型材料，其中：R1是任选取代的L-芳基或L-杂芳基，使得L是单键，烷基，CO或CO-或LX，与L □为烷基，X为O或S; R2是H或烷基; R3是任选被Hal取代的烷基; 并且R4是Hou Hal，其中所述材料是任何异构形式及其盐，用作药物。

4.

发明申请
NOVEL 2,3-DIHYDRO-1H-IMIDAZO(1,2-A)PYRIMIDIN-5-ONE DERIVATIVES, PREPARATION THEREOF, AND PHARMACEUTICAL USE THEREOF 有权
标题翻译：新的2,3-二氢-1H-咪唑并（1,2-A）嘧啶-5-酮衍生物，其制备方法及其药物用途

公开(公告)号：US20120142679A1

公开(公告)日：2012-06-07

申请号：US13381571

申请日：2010-07-01

申请人： Maurice Brolio , Annie Clauss , Youssef El Ahmad , Bruno Filoche-Romme , Frank Halley , Karl Andreas Karlsson , Gilbert Marciniak , Baptiste Ronan , Laurent Schio , Bertrand Vivet , Fabrice Viviani , Andre Zimmermann

发明人： Maurice Brolio , Annie Clauss , Youssef El Ahmad , Bruno Filoche-Romme , Frank Halley , Karl Andreas Karlsson , Gilbert Marciniak , Baptiste Ronan , Laurent Schio , Bertrand Vivet , Fabrice Viviani , Andre Zimmermann

IPC分类号： A61K31/5377 , A61P35/00 , A61P33/06 , A61P43/00 , A61P33/00 , A61P33/02 , C07D487/04 , A61P35/04

CPC分类号： C07D487/04 , A61K31/519 , A61K31/5377 , C07D413/14 , Y02A50/409 , Y02A50/411 , Y02A50/414 , Y02A50/415

摘要： The invention relates to the novel materials of formula (I), where R1 is an optionally substituted L-aryl or -heteroaryl, such that L is: an alkyl or CO, or LX, with Lbeing an alkyl and X being O or S; R2 is H or an alkyl; R3 is an alkyl optionally substituted by Hal; and R4 is Hou Hal, wherein said materials are in any isomeric form and the salts thereof, to be used as drugs.

摘要翻译： 本发明涉及式（I）的新型材料，其中R 1是任选取代的L-芳基或杂芳基，使得L是：烷基或CO或LX，其中烷基和X是O或S; R2是H或烷基; R3是任选被Hal取代的烷基; 并且R4是Hou Hal，其中所述材料是任何异构形式及其盐，用作药物。