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1.DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-alpha]IMIDAZOLE-3-CARBOXYLIC ACID AMIDES 有权
标题翻译: 6,7-二氢-5H-咪唑并[1,2-a]咪唑-3-羧酸酰胺的衍生物公开(公告)号:US20110224188A1
公开(公告)日:2011-09-15
申请号:US12745439
申请日:2008-11-20
申请人: Antonio Jose del Moral Barbosa , Joerg Martin Benzien , Steven Richard Brunette , Zhidong Chen , Derek Cogan , Donghong A. Gao , Alexander Heim-Riether , Joshua Courtney Horan , Jennifer A. Kowalski , Michael David Lawlor , Rene Marc Lemieux , Weimin Liu , Bryan Mckibben , Craig Andrew Miller , Neil Moss , Matt Aaron Tschantz , Zhaoming Xiong , Hui Yu , Yang Yu
发明人: Antonio Jose del Moral Barbosa , Joerg Martin Benzien , Steven Richard Brunette , Zhidong Chen , Derek Cogan , Donghong A. Gao , Alexander Heim-Riether , Joshua Courtney Horan , Jennifer A. Kowalski , Michael David Lawlor , Rene Marc Lemieux , Weimin Liu , Bryan Mckibben , Craig Andrew Miller , Neil Moss , Matt Aaron Tschantz , Zhaoming Xiong , Hui Yu , Yang Yu
IPC分类号: A61K31/501 , C07D487/04 , A61K31/454 , A61K31/4188 , A61K31/429 , A61K31/4439 , A61K31/496 , A61K31/4545 , A61K31/506 , A61P29/00 , A61P11/00 , A61P19/02 , A61P9/00 , A61P11/06 , A61P25/00 , A61P17/06 , A61P3/10
CPC分类号: C07D487/04
摘要: Derivatives of 6,7-dihydro-5H-imidazo[1,2-α]imidazole-3-carboxylic acid amide exhibit good inhibitory effect upon the interaction of CAMs and Leukointegrins and are thus useful in the treatment of inflammatory disease.
摘要翻译: 6,7-二氢-5H-咪唑并[1,2-α]咪唑-3-羧酸酰胺的衍生物对CAM和白细胞整合素的相互作用表现出良好的抑制作用,因此可用于治疗炎性疾病。
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2.Derivatives of 6,7-dihydro-5H-imidazo[1,2-alpha]imidazole-3-carboxylic acid amides 有权
标题翻译: 6,7-二氢-5H-咪唑并[1,2-a]咪唑-3-羧酸酰胺的衍生物公开(公告)号:US08552205B2
公开(公告)日:2013-10-08
申请号:US12745439
申请日:2008-11-20
申请人: Antonio Jose del Moral Barbosa, Jr. , Joerg Martin Bentzien , Steven Richard Brunette , Zhidong Chen , Derek Cogan , Donghong A. Gao , Alexander Heim-Riether , Joshua Courtney Horan , Jennifer A. Kowalski , Michael David Lawlor , Rene Marc Lemieux , Weimin Liu , Bryan McKibben , Craig Andrew Miller , Neil Moss , Matt Aaron Tschantz , Zhaoming Xiong , Hui Yu , Yang Yu
发明人: Antonio Jose del Moral Barbosa, Jr. , Joerg Martin Bentzien , Steven Richard Brunette , Zhidong Chen , Derek Cogan , Donghong A. Gao , Alexander Heim-Riether , Joshua Courtney Horan , Jennifer A. Kowalski , Michael David Lawlor , Rene Marc Lemieux , Weimin Liu , Bryan McKibben , Craig Andrew Miller , Neil Moss , Matt Aaron Tschantz , Zhaoming Xiong , Hui Yu , Yang Yu
IPC分类号: A61K31/4188 , C07D403/14 , C07D403/12 , C07D401/12 , C07D401/14
CPC分类号: C07D487/04
摘要: Derivatives of 6,7-dihydro-5H-imidazo[1,2-α]imidazole-3-carboxylic acid amide exhibit good inhibitory effect upon the interaction of CAMs and Leukointegrins and are thus useful in the treatment of inflammatory disease.
摘要翻译: 6,7-二氢-5H-咪唑并[1,2-α]咪唑-3-羧酸酰胺的衍生物对CAM和白血球素蛋白的相互作用表现出良好的抑制作用,因此可用于治疗炎性疾病。
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3.Derivatives of 6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-carboxylic acid amides 有权
标题翻译: 6,7-二氢-5H-咪唑并[1,2-a]咪唑-3-羧酸酰胺的衍生物公开(公告)号:US08575360B2
公开(公告)日:2013-11-05
申请号:US13375767
申请日:2010-05-26
申请人: Rene Marc Lemieux , Steven Richard Brunette , Joshua Courtney Horan , Jennifer A. Kowalski , Michael David Lawlor , Bryan McKibben , Craig Andrew Miller , Antonio J. M. Barbosa
发明人: Rene Marc Lemieux , Steven Richard Brunette , Joshua Courtney Horan , Jennifer A. Kowalski , Michael David Lawlor , Bryan McKibben , Craig Andrew Miller , Antonio J. M. Barbosa
IPC分类号: A61K31/4188 , C07D487/04 , C07D403/12 , C07D401/12 , C07D401/14
CPC分类号: C07D487/04 , C07D519/00
摘要: Derivatives of 6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-carboxylic acid amide exhibit good inhibitory effect upon the interaction of CAMs and Leukointegrins and are thus useful in the treatment of inflammatory disease.
摘要翻译: 6,7-二氢-5H-咪唑并[1,2-a]咪唑-3-羧酸酰胺的衍生物对CAM和白血球整合素的相互作用表现出良好的抑制作用,因此可用于治疗炎性疾病。
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4.DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-a]IMIDAZOLE-3-CARBOXYLIC ACID AMIDES 有权
标题翻译: 6,7-二氢-5H-咪唑并[1,2-a]咪唑-3-羧酸酰胺的衍生物公开(公告)号:US20120252817A1
公开(公告)日:2012-10-04
申请号:US13375767
申请日:2010-05-26
申请人: Rene Marc Lemieux , Steven Richard Brunette , Joshua Courtney Horan , Jennifer A. Kowalski , Michael David Lawlor , Bryan McKibben , Craig Andrew Miller , Antonio J. M. Barbosa
发明人: Rene Marc Lemieux , Steven Richard Brunette , Joshua Courtney Horan , Jennifer A. Kowalski , Michael David Lawlor , Bryan McKibben , Craig Andrew Miller , Antonio J. M. Barbosa
IPC分类号: C07D487/04 , A61K31/506 , A61K31/501 , A61P29/00 , A61P11/00 , A61P31/00 , A61P9/10 , A61P13/12 , A61P7/00 , A61P19/02 , A61P25/00 , A61P17/06 , A61P37/06 , A61P37/00 , A61P5/16 , A61P17/00 , A61P3/10 , A61P27/02 , A61P1/00 , A61P1/04 , A61P19/04 , A61P11/06 , A61K31/4439
CPC分类号: C07D487/04 , C07D519/00
摘要: Derivatives of 6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-carboxylic acid amide exhibit good inhibitory effect upon the interaction of CAMs and Leukointegrins and are thus useful in the treatment of inflammatory disease.
摘要翻译: 6,7-二氢-5H-咪唑并[1,2-a]咪唑-3-羧酸酰胺的衍生物对CAM和白血球整合素的相互作用表现出良好的抑制作用,因此可用于治疗炎性疾病。
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5.Derivatives of 6,7-dihydro-5h -imidazo[1,2-a] imidazole-3-sulfonic acid 有权
标题翻译: 6,7-二氢-5H-咪唑并[1,2-a]咪唑-3-磺酸的衍生物公开(公告)号:US07517897B2
公开(公告)日:2009-04-14
申请号:US11382940
申请日:2006-05-12
IPC分类号: A01N43/52
CPC分类号: C07D487/04
摘要: Derivatives of 6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonic acid which exhibit good inhibitory effect upon the interaction of CAMs and Leukointegrins and are thus useful in the treatment of inflammatory disease.
摘要翻译: 6,7-二氢-5H-咪唑并[1,2-a]咪唑-3-磺酸的衍生物,其对CAM和白细胞整合素的相互作用具有良好的抑制作用,因此可用于治疗炎性疾病。
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