Heterocyclic analogs of diphenylethylene compounds
    4.
    发明授权
    Heterocyclic analogs of diphenylethylene compounds 失效
    二苯基乙烯化合物的杂环类似物

    公开(公告)号:US07718682B2

    公开(公告)日:2010-05-18

    申请号:US12078662

    申请日:2008-04-02

    IPC分类号: A61K31/426

    摘要: Novel diphenylethylene compounds and derivatives thereof containing thiazolidinedione or oxazolidinedione moieties are provided which are effective in lowering blood glucose level, serum insulin, triglyceride and free fatty acid levels in animal models of Type II diabetes. The compounds are disclosed as useful for a variety of treatments including the treatment of inflammation, inflammatory and immunological diseases, insulin resistance, hyperlipidemia, coronary artery disease, cancer and multiple sclerosis.

    摘要翻译: 提供了含有噻唑烷二酮或恶唑烷二酮部分的新型二苯基乙烯化合物及其衍生物,其有效降低II型糖尿病动物模型中的血糖水平,血清胰岛素,甘油三酯和游离脂肪酸水平。 所述化合物被公开用于各种治疗,包括治疗炎症,炎症和免疫疾病,胰岛素抵抗,高脂血症,冠状动脉疾病,癌症和多发性硬化。

    Heterocyclic analogs of diphenylethylene compounds
    5.
    发明授权
    Heterocyclic analogs of diphenylethylene compounds 失效
    二苯基乙烯化合物的杂环类似物

    公开(公告)号:US07407978B2

    公开(公告)日:2008-08-05

    申请号:US10265902

    申请日:2002-10-08

    IPC分类号: A61K31/425

    摘要: Novel diphenylethylene compounds and derivatives thereof containing thiazolidinedione or oxazolidinedione moieties are provided which are effective in lowering blood glucose level, serum insulin, triglyceride and free fatty acid levels in animal models of Type II diabetes. The compounds are disclosed as useful for a variety of treatments including the treatment of inflammation, inflammatory and immunological diseases, insulin resistance, hyperlipidemia, coronary artery disease, cancer and multiple sclerosis.

    摘要翻译: 提供了含有噻唑烷二酮或恶唑烷二酮部分的新型二苯基乙烯化合物及其衍生物,其有效降低II型糖尿病动物模型中的血糖水平,血清胰岛素,甘油三酯和游离脂肪酸水平。 所述化合物被公开用于各种治疗,包括治疗炎症,炎症和免疫疾病,胰岛素抵抗,高脂血症,冠状动脉疾病,癌症和多发性硬化。

    Apparatus and method for hydroforming a tubular part
    6.
    发明申请
    Apparatus and method for hydroforming a tubular part 审中-公开
    用于液压成形管状部件的装置和方法

    公开(公告)号:US20050126243A1

    公开(公告)日:2005-06-16

    申请号:US10399192

    申请日:2001-10-16

    申请人: Arthur Lee

    发明人: Arthur Lee

    CPC分类号: B21D26/045

    摘要: A method and apparatus for shaping a raw tube into a formed part. The part can be configured within a die assembly including a hydroforming die structure and a pair of tube-engaging punches. The punches are inserted into the ends of the raw tube to shape the ends into the desired configuration. The middle portion of the raw tube is shaped into the desired configuration by hydroforming. Thus, the method and apparatus can shape the raw tube along its entire length, leaving no remnants of the raw tube that must be trimmed away.

    摘要翻译: 一种用于将原料管成形为成形部件的方法和装置。 该部件可以配置在包括液压成形模具结构和一对管接合冲头的模具组件内。 将冲头插入生管的端部以将端部成形为所需的构造。 原料管的中间部分通过液压成型成形为所需的构型。 因此,该方法和装置可以沿着其整个长度对原料管进行成形,不会将原始管的残留物修剪掉。

    GAMING SYSTEM AND METHOD OF PROVIDING AN ELECTRONIC GAME WITH A SCALING FACTOR
    7.
    发明申请
    GAMING SYSTEM AND METHOD OF PROVIDING AN ELECTRONIC GAME WITH A SCALING FACTOR 有权
    游戏系统和提供具有缩放因子的电子游戏的方法

    公开(公告)号:US20130084940A1

    公开(公告)日:2013-04-04

    申请号:US13471697

    申请日:2012-05-15

    IPC分类号: A63F13/10 A63F13/00

    摘要: A gaming machine and method are provided which allow a player to play a gaming machine. The gaming machine and method allow a player to make a wager, display a first game on a display device, generate an outcome associated with the first game, and award the player an award for the first game based at least in part on the generated first game outcome. In addition, the gaming machine determines if a triggering condition occurred, displays a second game if the triggering condition has occurred, and calculates a current trigger cycle of the generated second game. The current trigger cycle is equal to a number of first games played after an occurrence of a previous second game triggering condition. The player is provided an award for the second game based at least in part on the second game current trigger cycle.

    摘要翻译: 提供了允许玩家玩游戏机的游戏机和方法。 游戏机和方法允许玩家进行下注,在显示设备上显示第一游戏,产生与第一游戏相关联的结果,并且至少部分地基于生成的第一游戏向玩家授予第一游戏的奖励 游戏结局。 此外,游戏机确定是否发生触发条件,如果触发条件已经发生则显示第二游戏,并且计算所产生的第二游戏的当前触发周期。 当前的触发周期等于在先前的第二个游戏触发条件发生之后播放的第一个游戏的数量。 该玩家至少部分地基于第二游戏当前触发周期为第二游戏提供奖励。

    Novel heterocyclic analogs of diphenylethylene compounds
    8.
    发明申请
    Novel heterocyclic analogs of diphenylethylene compounds 失效
    二苯基乙烯化合物的新型杂环类似物

    公开(公告)号:US20080293949A1

    公开(公告)日:2008-11-27

    申请号:US12078662

    申请日:2008-04-02

    IPC分类号: C07D277/14

    摘要: Novel diphenylethylene compounds and derivatives thereof containing thiazolidinedione or oxazolidinedione moieties are provided which are effective in lowering blood glucose level, serum insulin, triglyceride and free fatty acid levels in animal models of Type II diabetes. The compounds are disclosed as useful for a variety of treatments including the treatment of inflammation, inflammatory and immunological diseases, insulin resistance, hyperlipidemia, coronary artery disease, cancer and multiple sclerosis.

    摘要翻译: 提供了含有噻唑烷二酮或恶唑烷二酮部分的新型二苯基乙烯化合物及其衍生物,其有效降低II型糖尿病动物模型中的血糖水平,血清胰岛素,甘油三酯和游离脂肪酸水平。 所述化合物被公开用于各种治疗,包括治疗炎症,炎症和免疫疾病,胰岛素抵抗,高脂血症,冠状动脉疾病,癌症和多发性硬化。

    Lubricant feed system
    10.
    发明授权
    Lubricant feed system 失效
    润滑剂进料系统

    公开(公告)号:US4094382A

    公开(公告)日:1978-06-13

    申请号:US699001

    申请日:1976-06-21

    申请人: Arthur Lee

    发明人: Arthur Lee

    IPC分类号: B27B17/12 F16N13/08

    CPC分类号: B27B17/12

    摘要: A lubricant feed system for use in lubricating the cutting attachments of a chain saw having an internal combustion engine and a lubricant tank. The feed system has a system of passageways permitting flow of lubricant from the tank to the guide bar. A check valve and a manually operable plunger are positioned in the passageway and spaced from each other to define a first chamber. The check valve permits flow from the tank to the bar pad and is openable by pressure in the tank. A metering valve for regulating the flow from the check valve to the bar pad is reciprocable between a closed and an opened position. The reciprocation and thus the position of the valve are controllable by manually operable means extending from the metering valve to the exterior. The metering valve has means to urge it to the closed position. The urging means exerts a force that can be overcome by operation of the plunger. There are means to permit the metering valve to move to a fully open position by the operation of the plunger regardless of the position of the metering valve. Thus operation of the plunger closes the check valve, opens fully the metering valve and forces lubricant contained in the first chamber through the system of passageways to clear any obstruction in said passageways.

    摘要翻译: 一种用于润滑具有内燃机和润滑剂罐的链锯的切割附件的润滑剂进料系统。 进料系统具有允许润滑剂从罐到导杆流动的通道系统。 止回阀和可手动操作的柱塞定位在通道中并且彼此间隔开以限定第一室。 止回阀允许从罐移动到杆垫,并且可以通过罐中的压力打开。 用于调节从止回阀到杆垫的流量的计量阀可在闭合位置和打开位置之间往复运动。 阀的往复运动以及因此的位置可通过从计量阀向外部延伸的手动操作的装置来控制。 计量阀具有将其推至关闭位置的装置。 推动装置施加能够通过柱塞的操作来克服的力。 存在允许计量阀通过柱塞的操作而移动到完全打开位置的方式,而与计量阀的位置无关。 因此,柱塞的操作关闭止回阀,完全打开计量阀,并通过通道系统迫使容纳在第一腔室中的润滑剂清除所述通道中的任何障碍物。