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公开(公告)号：US08536207B2
公开(公告)日：2013-09-17
申请号：US13479485
申请日：2012-05-24
IPC分类号： A61K31/42
CPC分类号： A61K9/0048 , A61K9/06 , A61K9/08 , A61K9/2018 , A61K31/095 , A61K31/26 , Y10S514/912
摘要： A method for treating a keratoconjunctival disorder, wherein the keratoconjunctival disorder comprises at least one disorder selected from the group consisting of a superficial punctate keratopathy, a corneal epithelial defect, corneal erosion, a corneal ulcer, a conjunctival epithelial defect, keratoconjunctivitis sicca, superior limbic keratoconjunctivitis, filamentary keratoconjunctivitis, keratitis and conjunctivitis, and wherein the method comprises orally administering from 3 mg/kg to 30 mg/kg per day of 2-phenyl-1,2-benzisoselenazol-3(2H)-one or a salt thereof to a patient in need thereof.
摘要翻译： 一种治疗角膜结膜疾病的方法，其中所述角膜结膜疾病包括至少一种选自浅表性点状角膜病，角膜上皮缺损，角膜侵蚀，角膜溃疡，结膜上皮缺损，圆锥形结膜炎，上颌骨 角结膜炎，角膜结膜炎，角膜炎和结膜炎，并且其中所述方法包括将每日3mg / kg至30mg / kg的2-苯基-1,2-苯并异硒唑（3H）酮或其盐口服给予 有需要的患者。
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公开(公告)号：US20090105313A1
公开(公告)日：2009-04-23
申请号：US11920477
申请日：2006-05-17
IPC分类号： A61K31/41 , C07D293/12 , A61P27/02
CPC分类号： A61K9/0048 , A61K9/06 , A61K9/08 , A61K9/2018 , A61K31/095 , A61K31/26 , Y10S514/912
摘要： An object of the present invention is to provide a new medicinal use of 2-phenyl-1,2-benzisoselenazol-3(2H)-one or a salt thereof. 2-Phenyl-1,2-benzisoselenazol-3(2H)-one or a salt thereof exhibits an excellent prevention and improvement effect in corneal disorder models, and is therefore useful as a preventive or therapeutic agent for a keratoconjunctival disorder such as dry eye, superficial punctate keratopathy, corneal epithelial defects, corneal erosion, corneal ulcer, conjunctival epithelial defects, keratoconjunctivitis sicca, superior limbic keratoconjunctivitis, filamentary keratoconjunctivitis, keratitis or conjunctivitis.
摘要翻译： 本发明的目的是提供2-苯基-1,2-苯并异硒唑（3H）酮或其盐的新药用途。 2-苯基-1,2-苯并异硒唑-3（2H） - 酮或其盐在角膜障碍模型中表现出优异的预防和改善作用，因此可用作角膜结膜疾病如干眼症的预防或治疗剂 ，浅表性点状角膜病变，角膜上皮缺损，角膜侵蚀，角膜溃疡，结膜上皮缺损，结膜炎角膜结膜炎，上限角膜结膜炎，丝状角膜结膜炎，角膜炎或结膜炎。
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公开(公告)号：US20120232119A1
公开(公告)日：2012-09-13
申请号：US13479485
申请日：2012-05-24
CPC分类号： A61K9/0048 , A61K9/06 , A61K9/08 , A61K9/2018 , A61K31/095 , A61K31/26 , Y10S514/912
摘要： A method for treating a keratoconjunctival disorder, wherein the keratoconjunctival disorder comprises at least one disorder selected from the group consisting of a superficial punctate keratopathy, a corneal epithelial defect, corneal erosion, a corneal ulcer, a conjunctival epithelial defect, keratoconjunctivitis sicca, superior limbic keratoconjunctivitis, filamentary keratoconjunctivitis, keratitis and conjunctivitis, and wherein the method comprises orally administering from 3 mg/kg to 30 mg/kg per day of 2-phenyl-1,2-benzisoselenazol-3(2H)-one or a salt thereof to a patient in need thereof.
摘要翻译： 一种治疗角膜结膜疾病的方法，其中所述角膜结膜疾病包括至少一种选自浅表性点状角膜病，角膜上皮缺损，角膜侵蚀，角膜溃疡，结膜上皮缺损，圆锥形结膜炎，上颌骨 角结膜炎，角膜结膜炎，角膜炎和结膜炎，并且其中所述方法包括将每日3mg / kg至30mg / kg的2-苯基-1,2-苯并异硒唑（3H）酮或其盐口服给予 有需要的患者。
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公开(公告)号：US08222283B2
公开(公告)日：2012-07-17
申请号：US11920477
申请日：2006-05-17
IPC分类号： A61K31/42
CPC分类号： A61K9/0048 , A61K9/06 , A61K9/08 , A61K9/2018 , A61K31/095 , A61K31/26 , Y10S514/912
摘要： An object of the present invention is to provide a new medicinal use of 2-phenyl-1,2-benzisoselenazol-3(2H)-one or a salt thereof. 2-Phenyl-1,2-benzisoselenazol-3(2H)-one or a salt thereof exhibits an excellent prevention and improvement effect in corneal disorder models, and is therefore useful as a preventive or therapeutic agent for a keratoconjunctival disorder such as dry eye, superficial punctate keratopathy, corneal epithelial defects, corneal erosion, corneal ulcer, conjunctival epithelial defects, keratoconjunctivitis sicca, superior limbic keratoconjunctivitis, filamentary keratoconjunctivitis, keratitis or conjunctivitis.
摘要翻译： 本发明的目的是提供2-苯基-1,2-苯并异硒唑（3H）酮或其盐的新药用途。 2-苯基-1,2-苯并异硒唑-3（2H） - 酮或其盐在角膜障碍模型中表现出优异的预防和改善作用，因此可用作角膜结膜疾病如干眼症的预防或治疗剂 ，浅表性点状角膜病变，角膜上皮缺损，角膜侵蚀，角膜溃疡，结膜上皮缺损，结膜炎角膜结膜炎，上限角膜结膜炎，丝状角膜结膜炎，角膜炎或结膜炎。
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公开(公告)号：US20110114739A1
公开(公告)日：2011-05-19
申请号：US12927441
申请日：2010-11-15
申请人： Haruki Misumi , Takuya Kataoka , Koji Ota , Michio Nishikawa , Shinichirou Hirai , Yoshiaki Suzuki , Akihiro Haraguchi , Katsuji Kuwada , Yasuhiro Sagou
发明人： Haruki Misumi , Takuya Kataoka , Koji Ota , Michio Nishikawa , Shinichirou Hirai , Yoshiaki Suzuki , Akihiro Haraguchi , Katsuji Kuwada , Yasuhiro Sagou
CPC分类号： B60H1/00742 , B60H2001/00992 , Y02T10/88
摘要： When there is no occupant in seats other than a driver seat during a foot mode, an air-conditioning controller executes a single seat concentration mode to prevent blowing of warm air to a passenger seat and a backseat by closing foot outlets on a passenger seat side and a backseat side. In this case, in order to maintain an air volume blown from the foot outlet on a driver seat side when the controller changes the mode from the normal foot mode to the single seat concentration mode, the controller sets a blower level to be lower than in the case of the normal foot mode with respect to the same target blown air temperature. Thus, an electric power consumed by an electric motor of a blower can be reduced, thereby realizing energy saving.
摘要翻译： 当在脚踏模式期间在驾驶席以外的座椅中没有乘客时，空调控制器执行单座集中模式，以防止乘客座椅侧的脚出口关闭乘客座椅和后座椅的暖风 和后座侧。 在这种情况下，当控制器将模式从正常脚踏模式改变为单座浓缩模式时，为了保持从驾驶员座侧的脚出口吹出的空气量，控制器将鼓风机水平设定为低于 相对于相同目标吹风温度的正常脚模式的情况。 因此，可以减少由鼓风机的电动机消耗的电力，从而实现节能。
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公开(公告)号：US20120142264A1
公开(公告)日：2012-06-07
申请号：US13308862
申请日：2011-12-01
申请人： Yasuhiro Sagou , Manabu Maeda , Shinichirou Hirai , Yoshinori Yanagimachi , Koji Wakabayashi , Koji Ota
发明人： Yasuhiro Sagou , Manabu Maeda , Shinichirou Hirai , Yoshinori Yanagimachi , Koji Wakabayashi , Koji Ota
IPC分类号： B60H1/24
CPC分类号： B60H1/00842 , B60H1/00735 , B60H1/00742 , B60H1/00764
摘要： A vehicle air conditioner includes a blower for blowing air into a space of a vehicle compartment, and an air-conditioning mode switching portion for switching between air conditioning modes. The air conditioning modes include a normal air conditioning mode in which air conditioning of a specific region including a driver seat and air conditioning of a non-specific region not including the specific region in the space of the vehicle compartment are performed, and a specific-region prioritizing air conditioning mode in which an air conditioning capability for the non-specific region is decreased as compared to the normal air conditioning mode. The air-conditioning mode switching portion adjusts the air conditioning capability for the non-specific region based on a pressure of air drawn into the blower, in the specific-region prioritizing air conditioning mode.
摘要翻译： 车辆空调包括用于将空气吹入车厢的空间的鼓风机和用于在空调模式之间切换的空调模式切换部。 空调模式包括正常的空调模式，其中执行包括驾驶员座椅的特定区域的空调和不包括车厢空间中的特定区域的非特定区域的空调， 区域优先空调模式，其中与正常空调模式相比，非特定区域的空气调节能力降低。 空调模式切换部在特定区域优先空调模式下，基于吸入鼓风机的空气的压力来调整非特定区域的空调能力。
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公开(公告)号：US09950589B2
公开(公告)日：2018-04-24
申请号：US13308862
申请日：2011-12-01
申请人： Yasuhiro Sagou , Manabu Maeda , Shinichirou Hirai , Yoshinori Yanagimachi , Koji Wakabayashi , Koji Ota
发明人： Yasuhiro Sagou , Manabu Maeda , Shinichirou Hirai , Yoshinori Yanagimachi , Koji Wakabayashi , Koji Ota
CPC分类号： B60H1/00842 , B60H1/00735 , B60H1/00742 , B60H1/00764
摘要： A vehicle air conditioner includes a blower for blowing air into a space of a vehicle compartment, and an air-conditioning mode switching portion for switching between air conditioning modes. The air conditioning modes include a normal air conditioning mode in which air conditioning of a specific region including a driver seat and air conditioning of a non-specific region not including the specific region in the space of the vehicle compartment are performed, and a specific-region prioritizing air conditioning mode in which an air conditioning capability for the non-specific region is decreased as compared to the normal air conditioning mode. The air-conditioning mode switching portion adjusts the air conditioning capability for the non-specific region based on a pressure of air drawn into the blower, in the specific-region prioritizing air conditioning mode.
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公开(公告)号：US09643472B2
公开(公告)日：2017-05-09
申请号：US14112607
申请日：2012-04-09
IPC分类号： B60H1/00
CPC分类号： B60H1/00878 , B60H1/00028 , B60H1/00849 , B60H2001/00085
摘要： A control part controls a first opening-and-closing part to close either one of a first outside air introduction port and a first inside air introduction port when it is determined that outside air introduced from the first outside air introduction port flows into a passenger compartment through the first inside air introduction port, and controls a second opening-and-closing part to close either one of a second outside air introduction port and a second inside air introduction port when it is determined that outside air introduced from the second outside air introduction port flows into the passenger compartment through the second inside air introduction port.
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公开(公告)号：US09188357B2
公开(公告)日：2015-11-17
申请号：US13068739
申请日：2011-05-19
CPC分类号： F24F11/0034 , B60H1/00742 , B60H1/00842 , B60H1/00849 , B60H2001/00192 , F24F11/30 , F24F2120/10 , F24F2120/12
摘要： A vehicle air conditioner includes a heating heat exchanger, a first temperature adjustment mechanism for adjusting a temperature of air to be blown toward a driver's seat side in a vehicle compartment, and a second temperature adjustment mechanism for adjusting a temperature of air to be blown toward a front-passenger's seat side in the vehicle compartment. In the vehicle air conditioner, the first and second temperature adjustment mechanisms are controlled to perform a one-seat priority mode control such that the temperature of air to be blown toward the front-passenger's seat side is lower than the temperature of air to be blown toward the driver's seat side, when only the driver is in the vehicle compartment and the heating condition is determined as the air conditioning state.
摘要翻译： 一种车辆空调装置，包括加热用热交换器，用于调节向车厢内的驾驶席侧吹出的空气的温度的第一温度调节机构，以及用于调节被吹送空气的温度的第二温度调节机构 车厢内的前排乘客座椅侧。 在车辆空调机中，控制第一和第二温度调节机构，进行单座优先模式控制，使得向前乘客座椅侧吹出的空气的温度低于吹出空气的温度 当驾驶员只在车厢内并且加热条件被确定为空调状态时，朝向驾驶席侧。
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公开(公告)号：US20140045417A1
公开(公告)日：2014-02-13
申请号：US14112607
申请日：2012-04-09
IPC分类号： B60H1/00
CPC分类号： B60H1/00878 , B60H1/00028 , B60H1/00849 , B60H2001/00085
摘要： A control part controls a first opening-and-closing part to close either one of a first outside air introduction port and a first inside air introduction port when it is determined that outside air introduced from the first outside air introduction port flows into a passenger compartment through the first inside air introduction port, and controls a second opening-and-closing part to close either one of a second outside air introduction port and a second inside air introduction port when it is determined that outside air introduced from the second outside air introduction port flows into the passenger compartment through the second inside air introduction port.
摘要翻译： 当确定从第一外部空气引入口引入的外部空气流入乘客室时，控制部件控制第一开闭部分以关闭第一外部空气导入口和第一内部空气导入口中的任一个 通过第一内部空气引入口，并且当确定从第二外部空气引入物引入的外部空气被确定时，控制第二开闭部分以关闭第二外部空气引入口和第二内部空气引入口中的任一个 端口通过第二内部空气引入口流入乘客舱。
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