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公开(公告)号:US08084200B2
公开(公告)日:2011-12-27
申请号:US12402434
申请日:2009-03-11
申请人: Avi J. Ashkenazi , Gretchen Frantz , Audrey Goddard , Lino Gonzalez , Austin L. Gurney , Paul Polakis , Andrew Polson , William I. Wood , Thomas D. Wu , Zemin Zhang
发明人: Avi J. Ashkenazi , Gretchen Frantz , Audrey Goddard , Lino Gonzalez , Austin L. Gurney , Paul Polakis , Andrew Polson , William I. Wood , Thomas D. Wu , Zemin Zhang
IPC分类号: C12Q1/68
CPC分类号: C07K16/30 , A61K2039/505
摘要: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号:US20090186363A1
公开(公告)日:2009-07-23
申请号:US12402434
申请日:2009-03-11
申请人: Avi J. Ashkenazi , Gretchen Frantz , Audrey Goddard , Lino Gonzalez , Austin L. Gurney , Paul Polakis , Andrew Polson , William I. Wood , Thomas D. Wu , Zemin Zhang
发明人: Avi J. Ashkenazi , Gretchen Frantz , Audrey Goddard , Lino Gonzalez , Austin L. Gurney , Paul Polakis , Andrew Polson , William I. Wood , Thomas D. Wu , Zemin Zhang
IPC分类号: C12Q1/68 , G01N33/574
CPC分类号: C07K16/30 , A61K2039/505
摘要: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
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公开(公告)号:US07056736B2
公开(公告)日:2006-06-06
申请号:US09989328
申请日:2001-11-19
申请人: Avi J. Ashkenazi , Kevin P. Baker , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Sherman Fong , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Ivar J. Kljavin , Mary A. Napier , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , P. Mickey Williams , William I. Wood , Zemin Zhang
发明人: Avi J. Ashkenazi , Kevin P. Baker , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Sherman Fong , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Ivar J. Kljavin , Mary A. Napier , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , P. Mickey Williams , William I. Wood , Zemin Zhang
CPC分类号: C07K14/47
摘要: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US07390879B2
公开(公告)日:2008-06-24
申请号:US10226739
申请日:2002-08-23
申请人: Avi J. Ashkenazi , Kevin P. Baker , David A. Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Ivar J. Kljavin , Jennie P. Mather , Mary A. Napier , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , P. Mickey Williams , William I. Wood , Zemin Zhang
发明人: Avi J. Ashkenazi , Kevin P. Baker , David A. Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Ivar J. Kljavin , Jennie P. Mather , Mary A. Napier , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , P. Mickey Williams , William I. Wood , Zemin Zhang
CPC分类号: C07K14/47
摘要: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US07317092B2
公开(公告)日:2008-01-08
申请号:US10066273
申请日:2002-02-01
申请人: Avi J. Ashkenazi , Kevin P. Baker , David A. Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Ivar J. Kljavin , Jennie P. Mather , Mary A. Napier , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , P. Mickey Williams , William I. Wood , Zemin Zhang
发明人: Avi J. Ashkenazi , Kevin P. Baker , David A. Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Sherman Fong , Wei-Qiang Gao , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , Ivar J. Kljavin , Jennie P. Mather , Mary A. Napier , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , P. Mickey Williams , William I. Wood , Zemin Zhang
CPC分类号: A61K38/17 , C07H21/04 , C07K14/435 , C07K16/40 , C12N5/06 , C12N9/00 , C12P21/02 , C12P21/06 , G01N33/53 , Y02A50/473
摘要: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US07070955B2
公开(公告)日:2006-07-04
申请号:US09989733
申请日:2001-11-20
申请人: Avi J. Ashkenazi , Kevin P. Baker , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Sherman Fong , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Ivar J. Kljavin , Mary A. Napier , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , P. Mickey Williams , William I. Wood , Zemin Zhang
发明人: Avi J. Ashkenazi , Kevin P. Baker , David Botstein , Luc Desnoyers , Dan L. Eaton , Napoleone Ferrara , Sherman Fong , Hanspeter Gerber , Mary E. Gerritsen , Audrey Goddard , Paul J. Godowski , J. Christopher Grimaldi , Austin L. Gurney , Ivar J. Kljavin , Mary A. Napier , James Pan , Nicholas F. Paoni , Margaret Ann Roy , Timothy A. Stewart , Daniel Tumas , Colin K. Watanabe , P. Mickey Williams , William I. Wood , Zemin Zhang
CPC分类号: C07K14/4747 , C07K14/47
摘要: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US07691978B2
公开(公告)日:2010-04-06
申请号:US11535718
申请日:2006-09-27
申请人: Avi J. Ashkenazi , Dan L. Eaton , Audrey Goddard , Austin L. Gurney , William I. Wood , Thomas D. Wu
发明人: Avi J. Ashkenazi , Dan L. Eaton , Audrey Goddard , Austin L. Gurney , William I. Wood , Thomas D. Wu
CPC分类号: C07K16/30 , C12Q1/6886 , C12Q2600/158
摘要: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
摘要翻译: 本发明涉及用于哺乳动物肿瘤诊断和治疗的物质组合物,以及使用这些物质组合物的方法。
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公开(公告)号:US07547507B2
公开(公告)日:2009-06-16
申请号:US11046650
申请日:2005-01-28
申请人: Avi J. Ashkenazi , Dan L. Eaton , Audrey Goddard , Austin L. Gurney , William I. Wood , Thomas D. Wu
发明人: Avi J. Ashkenazi , Dan L. Eaton , Audrey Goddard , Austin L. Gurney , William I. Wood , Thomas D. Wu
CPC分类号: C07K16/30 , C12Q1/6886 , C12Q2600/158
摘要: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
摘要翻译: 本发明涉及用于哺乳动物肿瘤诊断和治疗的物质组合物,以及使用这些物质组合物的方法。
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公开(公告)号:US20100145027A1
公开(公告)日:2010-06-10
申请号:US12702086
申请日:2010-02-08
申请人: Avi J. Ashkenazi , Dan L. Eaton , Audrey Goddard , Austin L. Gurney , William I. Wood , Thomas D. Wu
发明人: Avi J. Ashkenazi , Dan L. Eaton , Audrey Goddard , Austin L. Gurney , William I. Wood , Thomas D. Wu
IPC分类号: C07K16/18 , C07K14/435
CPC分类号: C07K16/30 , C12Q1/6886 , C12Q2600/158
摘要: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
摘要翻译: 本发明涉及用于哺乳动物肿瘤诊断和治疗的物质组合物,以及使用这些物质组合物的方法。
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公开(公告)号:US08097700B2
公开(公告)日:2012-01-17
申请号:US12702086
申请日:2010-02-08
申请人: Avi J. Ashkenazi , Dan L. Eaton , Audrey Goddard , Austin L. Gurney , William I. Wood , Thomas D. Wu
发明人: Avi J. Ashkenazi , Dan L. Eaton , Audrey Goddard , Austin L. Gurney , William I. Wood , Thomas D. Wu
IPC分类号: C07K14/00 , C07K14/435 , C07K14/46 , C07K14/47
CPC分类号: C07K16/30 , C12Q1/6886 , C12Q2600/158
摘要: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
摘要翻译: 本发明涉及用于哺乳动物肿瘤诊断和治疗的物质组合物,以及使用这些物质组合物的方法。
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