公开(公告)号：US20190275137A1

公开(公告)日：2019-09-12

申请号：US16420192

申请日：2019-05-23

申请人： Biological Mimetics Inc.

发明人： Peter L. Nara ,  Gregory J. Tobin ,  George Lin

IPC分类号： A61K39/12 ,  A61K39/145 ,  C12N7/00 ,  C07K14/005

摘要： Novel compositions useful as influenza immunogens are provided. The compositions enable a host response to immunogen sites normally not recognized by a host.

公开(公告)号：US12042533B2

公开(公告)日：2024-07-23

申请号：US17041870

申请日：2019-03-29

申请人： BIOLOGICAL MIMETICS, INC. ,  THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC.

发明人： Gregory J. Tobin ,  Michael J. Daly

IPC分类号： A61K39/12 ,  C12N7/04 ,  C12N13/00 ,  A61K39/00

CPC分类号： A61K39/12 ,  C12N7/04 ,  C12N13/00 ,  A61K2039/5252 ,  C12N2770/32634 ,  C12N2770/32661

摘要： Compositions useful as poliovirus immunogens are provided along with methods and compositions for preparing the same. Compositions comprising poliovirus immunogens can enable a host response that includes virus-neutralizing antibodies which can protect the host from infection and/or disease.

公开(公告)号：US20240316177A1

公开(公告)日：2024-09-26

申请号：US18739648

申请日：2024-06-11

申请人： BIOLOGICAL MIMETICS, INC. ,  THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC.

发明人： Gregory J. Tobin ,  Michael J. Daly

IPC分类号： A61K39/12 ,  A61K39/00 ,  C12N7/04 ,  C12N13/00

CPC分类号： A61K39/12 ,  C12N7/04 ,  C12N13/00 ,  A61K2039/5252 ,  C12N2770/32634 ,  C12N2770/32661

摘要： Compositions useful as poliovirus immunogens are provided along with methods and compositions for preparing the same. Compositions comprising poliovirus immunogens can enable a host response that includes virus-neutralizing antibodies which can protect the host from infection and/or disease.

公开(公告)号：US20180071383A1

公开(公告)日：2018-03-15

申请号：US14793732

申请日：2015-07-07

申请人： BIOLOGICAL MIMETICS INC.

发明人： Gregory J. Tobin ,  Peter L. Nara ,  George Lin

IPC分类号： A61K39/145 ,  C07K16/10 ,  A61K39/12 ,  A61K39/00

CPC分类号： A61K39/145 ,  A61K39/12 ,  A61K2039/5258 ,  A61K2039/545 ,  A61K2039/55566 ,  A61K2039/70 ,  C07K16/1018 ,  C07K2317/33 ,  C07K2317/76 ,  C12N2760/16034 ,  C12N2760/16134

摘要： Methods for providing novel compositions useful as influenza immunogens are provided. The compositions enable a host response to immunogen sites normally not recognized by a host. The novel immunogens can be used as vaccines or to develop antibodies.

公开(公告)号：US20240042001A1

公开(公告)日：2024-02-08

申请号：US18258842

申请日：2021-12-21

申请人： Biological Mimetics, Inc. ,  The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.

发明人： Gregory J. Tobin ,  Taralyn J. Wiggins ,  Michael J. Daly ,  Elena Gaidamakova ,  Vera Matrosova

IPC分类号： A61K39/02 ,  C12N1/36 ,  C12N1/20 ,  A61P31/04

CPC分类号： A61K39/0208 ,  C12N1/36 ,  C12N1/20 ,  A61P31/04 ,  A61K2039/522

摘要： Presented herein are inactivated A. baumannii immunogens. Also described herein are compositions including A. baumannii immunogens. Methods and compositions for preparing the same are also described.

公开(公告)号：US20150313989A1

公开(公告)日：2015-11-05

申请号：US14801770

申请日：2015-07-16

申请人： Biological Mimetics, Inc.

发明人： Peter L. Nara ,  Gregory J. Tobin ,  George Lin

IPC分类号： A61K39/145 ,  C12N7/00

CPC分类号： A61K39/12 ,  A61K39/145 ,  C07K14/005 ,  C12N7/00 ,  C12N2760/16034 ,  C12N2760/16122 ,  C12N2760/16134

摘要： Novel compositions useful as influenza immunogens are provided. The compositions enable a host response to immunogen sites normally not recognized by a host.

摘要翻译： 提供了可用作流感免疫原的新型组合物。 所述组合物使宿主对免疫原位点的反应通常不被宿主识别。