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公开(公告)号：US11511000B2
公开(公告)日：2022-11-29
申请号：US17196274
申请日：2021-03-09
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： David Donnelly , David K. Leung
Abstract: The invention relates to water soluble 18F-prosthetic groups and the synthesis and use of 18F-labeled biological molecules containing the 18F-prosthetic groups for imaging various processes within the body, for detecting the location of molecules associated with disease pathology, and for monitoring disease progression are disclosed.
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公开(公告)号：US11806409B2
公开(公告)日：2023-11-07
申请号：US17984825
申请日：2022-11-10
Applicant: Bristol-Myers Squibb Company
Inventor： David Donnelly , David K. Leung
CPC classification number: A61K51/088 , A61K49/0004 , C07K16/2818
Abstract: The invention relates to water soluble 18F-prosthetic groups and the synthesis and use of 18F-labeled biological molecules containing the 18F-prosthetic groups for imaging various processes within the body, for detecting the location of molecules associated with disease pathology, and for monitoring disease progression are disclosed.
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公开(公告)号：US11229713B2
公开(公告)日：2022-01-25
申请号：US15526584
申请日：2015-11-24
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： David Donnelly
Abstract: The invention relates to water soluble 18F-prosthetic groups and the synthesis and use of 18F-labeled biological molecules containing the 18F-prosthetic groups for imaging various processes within the body, for detecting the location of molecules associated with disease pathology, and for monitoring disease progression are disclosed.
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Patent Agency Ranking
公开(公告)号：US12194110B2
公开(公告)日：2025-01-14
申请号：US17483393
申请日：2021-09-23
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Paul E. Morin , David Donnelly , Dasa Lipovsek , Jochem Gokemeijer , Maria N. Jure-Kunkel , David Fabrizio , Martin C. Wright , Douglas Dischino , Samuel J. Bonacorsi, Jr. , Ralph Adam Smith , Virginie Lafont , Daniel Cohen
Abstract: Provided herein are novel 10Fn3 domains which specifically bind to PD-L1, as well as imaging agents based on the same for diagnostics.
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公开(公告)号：US11173219B2
公开(公告)日：2021-11-16
申请号：US16520965
申请日：2019-07-24
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Paul E. Morin , David Donnelly , Dasa Lipovsek , Jochem Gokemeijer , Maria Jure-Kunkel , David Fabrizio , Martin C. Wright , Douglas Dischino , Samuel J. Bonacorsi, Jr. , Ralph Adam Smith , Virginie LaFont , Daniel Cohen
Abstract: Provided herein are novel 10Fn3 domains which specifically bind to PD-L1, as well as imaging agents based on the same for diagnostics.
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公开(公告)号：US10994033B2
公开(公告)日：2021-05-04
申请号：US16305286
申请日：2017-05-31
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： David Donnelly , David K. Leung
Abstract: The invention relates to water soluble 18F-prosthetic groups and the synthesis and use 18F-labeled biological molecules containing the 18F-prosthetic groups for imaging various processes within the body, for detecting the location of molecules associated with disease pathology, and for monitoring disease progression are disclosed.
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公开(公告)号：US11344639B2
公开(公告)日：2022-05-31
申请号：US16305284
申请日：2017-05-31
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Paul E. Morin , David Donnelly , Dasa Lipovsek , Jochem Gokemeijer , Maria Jure-Kunkel , David Fabrizio , Martin C. Wright , Douglas Dischino , Samuel J. Bonacorsi, Jr. , Ralph Adam Smith , Virginie Lafont , Daniel Cohen , David K. Leung
Abstract: Provided herein are novel 10Fn3 domains which specifically bind to PD-L1, as well as imaging agents based on the same for diagnostics.
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公开(公告)号：US10406251B2
公开(公告)日：2019-09-10
申请号：US15529260
申请日：2015-11-24
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Paul E. Morin , David Donnelly , Dasa Lipovsek , Jochem Gokemeijer , Maria N. Jure-Kunkel , David Fabrizio , Martin C. Wright , Douglas Dischino , Samuel J. Bonacorsi, Jr. , Ralph Adam Smith , Virginie Lafont , Daniel Cohen
IPC: A61K51/08 , C07K14/78 , G01N33/60 , G01N33/68 , G01N33/574
Abstract: Provided herein are novel polypeptides comprising fibronectin type III tenth (10Fn3) domains which specifically bind to Programmed Death Ligand-1 (PD-L1), as well as imaging agents based on the same for diagnostics.
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