公开(公告)号：US11173219B2

公开(公告)日：2021-11-16

申请号：US16520965

申请日：2019-07-24

Applicant: BRISTOL-MYERS SQUIBB COMPANY

Inventor： Paul E. Morin ,  David Donnelly ,  Dasa Lipovsek ,  Jochem Gokemeijer ,  Maria Jure-Kunkel ,  David Fabrizio ,  Martin C. Wright ,  Douglas Dischino ,  Samuel J. Bonacorsi, Jr. ,  Ralph Adam Smith ,  Virginie LaFont ,  Daniel Cohen

IPC: A61K51/08 ,  C07K14/78 ,  G01N33/574 ,  C12N5/00 ,  C12N15/09 ,  G01N33/60 ,  G01N33/68

Abstract: Provided herein are novel 10Fn3 domains which specifically bind to PD-L1, as well as imaging agents based on the same for diagnostics.