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公开(公告)号：US20130224812A1
公开(公告)日：2013-08-29
申请号：US13770219
申请日：2013-02-19
Applicant: Bristol-Myers Squibb Company
Inventor： Animesh Goswami , Zhiwei Guo , Yuping Qiu
IPC: C12P7/62
CPC classification number: C12P7/62 , C12P7/42 , C12P41/00 , C12P41/005
Abstract: The present disclosure provides a method for the stereospecific hydrolysis of racemic 1,1-dialkyloxycarbonylcyclopropanes.
Abstract translation: 本公开提供了外消旋的1,1-二烷氧基羰基环丙烷的立体特异性水解的方法。
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公开(公告)号：US20150140610A1
公开(公告)日：2015-05-21
申请号：US14402231
申请日：2013-05-22
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Adrian Ortiz , Tamas Benkovics , Zhongping Shi , Prashant P. Deshpande , Zhiwei Guo , David R. Kronenthal , Chris Sfouggatakis
CPC classification number: C07H15/20 , C07D307/20 , C07D309/10 , C07D407/04 , C07H19/06 , C12P19/385
Abstract: A process for making the compound of Formula I utilizes the starting compound, together with sulfilimine and sulfoxide process steps later on.
Abstract translation: 制备式I化合物的方法利用起始化合物以及稍后的亚硫酰亚胺和亚砜工艺步骤。
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公开(公告)号：US09249171B2
公开(公告)日：2016-02-02
申请号：US14402231
申请日：2013-05-22
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Adrian Ortiz , Tamas Benkovics , Zhongping Shi , Prashant P. Deshpande , Zhiwei Guo , David R. Kronenthal , Chris Sfouggatakis
IPC: C07H15/20 , C07H19/06 , C12P19/38 , C07D309/10 , C07D407/04 , C07D307/20
CPC classification number: C07H15/20 , C07D307/20 , C07D309/10 , C07D407/04 , C07H19/06 , C12P19/385
Abstract: A process for making the compound of Formula I utilizes the starting compound, together with sulfilimine and sulfoxide process steps later on.
Abstract translation: 制备式I化合物的方法利用起始化合物以及稍后的亚硫酰亚胺和亚砜工艺步骤。
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公开(公告)号：US08828691B2
公开(公告)日：2014-09-09
申请号：US13770219
申请日：2013-02-19
Applicant: Bristol-Myers Squibb Company
Inventor： Animesh Goswami , Zhiwei Guo , Yuping Qiu
CPC classification number: C12P7/62 , C12P7/42 , C12P41/00 , C12P41/005
Abstract: The present disclosure provides a method for the stereospecific hydrolysis of racemic 1,1-dialkyloxycarbonylcyclopropanes.
Abstract translation: 本公开提供了外消旋的1,1-二烷氧基羰基环丙烷的立体特异性水解的方法。
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