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公开(公告)号：US5388578A
公开(公告)日：1995-02-14
申请号：US43269
申请日：1993-04-06
IPC分类号： A61B5/00 , A61B5/0245 , A61B5/04 , A61B5/0452 , A61B5/0472 , A61N1/37 , A61B5/042
CPC分类号： A61B5/04525 , A61B5/0031 , A61N1/3702
摘要： An implantable cardiac monitor is arranged for detecting both arrhythmias and ischemia of the human heart. The monitor includes subcutaneous electrodes for establishing electrical contact with the heart and a sense amplifier coupled to each electrode for generating an electrocardiogram of a heart beat sensed at each of the electrodes. The electrocardiograms are digitized and the digital samples thereof are stored in a memory. A microprocessor processes the digital samples of the electrocardiograms and generates characterizing data indicative of the physiology of the heart. The cardiac monitor includes telemetry to permit the cardiac data to be interrogated externally of the patient for obtaining the generated cardiac data indicative of arrhythmic and ischemic episodes.
摘要翻译： 一种植入式心脏监测器被安排用于检测人心脏的心律失常和缺血。 监测器包括用于与心脏建立电接触的皮下电极和耦合到每个电极的感测放大器，用于产生在每个电极处感测到的心跳的心电图。 将心电图数字化，并将其数字样本存储在存储器中。 微处理器处理心电图的数字样本并产生指示心脏生理学的特征数据。 心脏监测器包括遥测以允许心脏数据在患者外部询问，以获得指示心律失常和缺血发作的产生的心脏数据。
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公开(公告)号：US5313953A
公开(公告)日：1994-05-24
申请号：US820580
申请日：1992-01-14
IPC分类号： A61B5/00 , A61B5/0245 , A61B5/04 , A61B5/0452 , A61B5/0472 , A61N1/37 , A61B5/0432
CPC分类号： A61B5/04525 , A61B5/0031 , A61N1/3702
摘要： An implantable cardiac monitor is arranged for detecting both arrhythmias and ischemia of the human heart. The monitor includes subcutaneous electrodes for establishing electrical contact with the heart and a sense amplifier coupled to each electrode for generating an electrocardiogram of a heart beat sensed at each of the electrodes. The electrocardiograms are digitized and the digital samples thereof are stored in a memory. A microprocessor processes the digital samples of the electrocardiograms and generates characterizing data indicative of the physiology of the heart. The cardiac monitor includes telemetry to permit the cardiac data to be interrogated externally of the patient for obtaining the generated cardiac data indicative of arrhythmic and ischemic episodes.
摘要翻译： 一种植入式心脏监测器被安排用于检测人心脏的心律失常和缺血。 监测器包括用于与心脏建立电接触的皮下电极和耦合到每个电极的感测放大器，用于产生在每个电极处感测到的心跳的心电图。 将心电图数字化，并将其数字样本存储在存储器中。 微处理器处理心电图的数字样本并产生指示心脏生理学的特征数据。 心脏监测器包括遥测以允许心脏数据在患者外部询问，以获得指示心律失常和缺血发作的产生的心脏数据。
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公开(公告)号：US5282836A
公开(公告)日：1994-02-01
申请号：US965167
申请日：1992-10-23
CPC分类号： A61N1/3962 , A61N1/395
摘要： An implantable atrial defibrillator provides cardioverting electrical energy to the atria of a human heart in need of cardioversion. The atrial defibrillator includes a first detector for detecting atrial activity of the heart and an atrial fibrillation detector responsive to the first detector for determining when the atria of the heart are in need of cardioversion. The atrial defibrillator further includes a pacing output circuit responsive to the atrial fibrillation detector for pacing the ventricles of the heart at a pacing rate when the atria of the heart are in need of cardioversion and a cardioverter stage for applying the cardioverting electrical energy to the atria of the heart after the pacing output circuit has paced the ventricles for a predetermined number of cardiac cycles. The pacing output circuit stabilizes the cardiac rate of the heart prior to the application of the cardioverting electrical energy.
摘要翻译： 可植入心房除颤器为需要心脏复律的人心脏心房提供心律转复的电能。 心房除颤器包括用于检测心脏的心房活动的第一检测器和响应于第一检测器的心房颤动检测器，用于确定心脏心房何时需要心脏复律。 心房除颤器还包括响应于心房颤动检测器的起搏输出电路，用于在心脏心房需要心脏复律时以起搏速率起搏心室，并且将心脏转复器电位施加到心房 在起搏输出电路已经使心室起搏预定数量的心动周期之后的心脏。 起搏输出电路在应用转复电能之前稳定心脏的心率。
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公开(公告)号：US5330700A
公开(公告)日：1994-07-19
申请号：US761576
申请日：1991-09-18
CPC分类号： A61N1/0565 , Y10T428/12021 , Y10T428/12042
摘要： A porous electrode for pacemakers is comprised of a plurality of platinum globules sintered together to form a porous mass of semi-hemispherical shape at the end of a platinum electrode stem. The globules, which are themselves made by sintering together spherically-shaped particles of approximately one micron diameter, provide the globules with an irregular outer surface of high total surface area. The globules have diameters within a critical range of 40-200 microns. The large total surface area of the globules improves the sensing function of an electrode configuration of given size and surface area, while the globule diameters of 40-200 microns have been found to beneficially accommodate tissue ingrowth within the electrode. In a preferred method of making the electrode, the platinum globules, which are formed by sintering together platinum particles of much smaller size, are mixed with organic solvent and organic binder to form a paste. After application of the paste to the base of an electrode stem and pressing of the paste using a mold so as to form the paste into the desired semi-hemispherical shape, the electrode is heated to evaporate the organic solvent, and the electrode is then placed in a sintering furnace to sinter together the platinum globules and form the completed electrode.
摘要翻译： 用于起搏器的多孔电极由多个铂球组成，其在铂电极杆的末端烧结在一起以形成半球形的多孔质量块。 本身通过将大约一微米直径的球形颗粒烧结在一起的小球为球提供了具有高总表面积的不规则外表面。 小球具有在40-200微米的临界范围内的直径。 球的大的总表面积改善了给定尺寸和表面积的电极构型的感测功能，而发现40-200微米的球直径有利地适应电极内的组织向内生长。 在制造电极的优选方法中，将通过将较小尺寸的铂颗粒烧结在一起形成的铂球与有机溶剂和有机粘合剂混合以形成糊料。 在将糊剂施加到电极杆的基部并使用模具压制糊料以形成所需的半球形状的糊料之后，加热电极以蒸发有机溶剂，然后将电极放置 在烧结炉中烧结铂球并形成完成的电极。
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公开(公告)号：US5107856A
公开(公告)日：1992-04-28
申请号：US639643
申请日：1991-01-10
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61N2001/0582 , Y10S128/26
摘要： A suture sleeve for securing the leads of a multiple lead implantable medical device includes lead gripping and anchoring portions. The sleeve has a pair of flexible side walls and longitudinally extending channels for receiving the leads. The side walls of at least the gripping portion have longitudinally extending, confronting, spaced apart edges and comprises two layers one of which is formed of a soft plastic such as silicone and the other of which is formed of a harder but flexible material such as polysulfone. Sutures placed and tied about the gripping portion compress the sleeve about the leads. Tightening of the sutures brings the confronting edges of the gripping portion of the sleeve into engagement thereby precluding further compression of the sleeve and preventing damage to the leads.
摘要翻译： 用于固定多引线可植入医疗装置的引线的缝合套筒包括引线夹持和锚定部分。 套筒具有一对柔性侧壁和用于接收引线的纵向延伸通道。 至少握持部分的侧壁具有纵向延伸的面对的间隔开的边缘，并且包括两层，其中一层由诸如硅树脂的软塑料形成，另一层由较硬但柔性的材料形成，例如聚砜 。 围绕夹紧部分放置和捆扎的缝合线围绕引线压缩套筒。 缝合线的紧固使得套筒的抓握部分的相对边缘成为接合，从而排除套筒的进一步压缩并防止对引线的损坏。
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公开(公告)号：US5154183A
公开(公告)日：1992-10-13
申请号：US590898
申请日：1990-10-01
IPC分类号： A61N1/05
CPC分类号： A61N1/0587
摘要： A bipolar electrode assembly for attachment to heart tissue for use with a pacemaker. The assembly has a hub member with a helical screw-in coil that acts as a first electrode and is used to attach the assembly to the heart tissue. The assembly further comprises a plurality of appendages that extend from the hub member and each have an electrode segment of electrically conductive material. The electrode segment of the appendages can act together as a single second electrode, or alternatively as a separate, independent electrodes, which may selectively be used for pacing or sensing. The electrode segments not only act as electrodes, but also allows heart tissue to grow directly into the conductive material to help secure the assembly to the heart. The assembly also has apertures and grooves for suture connection of the assembly to the heart. Methods of manufacturing the assembly and connecting the assembly to a heart are also described.
摘要翻译： 用于附接到心脏组织以用于起搏器的双极电极组件。 该组件具有带有螺旋螺旋线圈的毂构件，其用作第一电极并且用于将组件附接到心脏组织。 组件还包括从轮毂构件延伸的多个附件，并且每个具有导电材料的电极段。 附件的电极段可以一起作为单个第二电极，或者可选地作为独立的独立电极，其可以选择性地用于起搏或感测。 电极段不仅用作电极，而且还允许心脏组织直接生长到导电材料中以有助于将组件固定到心脏。 组件还具有用于将组件缝合连接到心脏的孔和凹槽。 还描述了制造组件并将组件连接到心脏的方法。
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公开(公告)号：US5152298A
公开(公告)日：1992-10-06
申请号：US686095
申请日：1991-04-16
CPC分类号： A61B17/0401 , A61N1/057 , A61B2017/0414 , A61N2001/0582
摘要： A suture sleeve for anchoring the lead body of an implantable medical device, such as a cardiac pacemaker, includes an elongated tubular member having a lumen for receiving the lead body. The tubular member has external threads for receiving a threaded collar. The tubular member and collar have engaging, tapered surfaces whereby tightening of the collar on the tubular member compresses a portion of the tubular member into gripping engagement with the lead body. The tubular member and collar have surfaces which come into contact upon tightening of the collar so as to limit compression of the lead body and thereby prevent damage thereto.
摘要翻译： 用于固定可植入医疗装置（例如心脏起搏器）的引线主体的缝合套管包括具有用于接收引线体的内腔的细长管状构件。 管状构件具有用于接收螺纹套环的外螺纹。 管状构件和套环具有接合的锥形表面，由此管状构件上的套环的紧固将管状构件的一部分压缩成与引线主体夹紧接合。 管状构件和套环具有在紧固套环时接触的表面，以限制引线体的压缩，从而防止对其的损坏。
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公开(公告)号：US5097843A
公开(公告)日：1992-03-24
申请号：US507698
申请日：1990-04-10
IPC分类号： A61N1/05
CPC分类号： A61N1/0565 , Y10T428/12021 , Y10T428/12042
摘要： A porous electrode for pacemakers is comprised of a plurality of platinum globules sintered together to form a porous mass of semi-hemispherical shape at the end of a platinum electrode stem. The globules, which are themselves made by sintering together spherically-shaped particles of approximately one micron diameter, provide the globules with an irregular outer surface of high total surface area. The globules have diameters within a critical range of 40-200 microns. The large total surface area of the globules improves the sensing function of an electrode configuration of given size and surface area, while the globule diameters of 40-200 microns have been found to beneficially accommodate tissue ingrowth within the electrode. In a preferred method of making the electrode, the platinum globules, which are formed by sintering together platinum particles of much smaller size, are mixed with organic solvent and organic binder to form a paste. After application of the paste to the base of an electrode stem and pressing of the paste using a mold so as to form the paste into the desired semi-hemispherical shape, the electrode is heated to evaporate the organic solvent, and the electrode is then placed in a sintering furnace to sinter together the platinum globules and form the completed electrode.
摘要翻译： 用于起搏器的多孔电极由多个铂球组成，其在铂电极杆的末端烧结在一起以形成半球形的多孔质量块。 本身通过将大约一微米直径的球形颗粒烧结在一起的小球为球提供了具有高总表面积的不规则外表面。 小球具有在40-200微米的临界范围内的直径。 球的大的总表面积改善了给定尺寸和表面积的电极构型的感测功能，而发现40-200微米的球直径有利地适应电极内的组织向内生长。 在制造电极的优选方法中，将通过将较小尺寸的铂颗粒烧结在一起形成的铂球与有机溶剂和有机粘合剂混合以形成糊料。 在将糊剂施加到电极杆的基部并使用模具压制糊料以形成所需的半球形状的糊料之后，加热电极以蒸发有机溶剂，然后将电极放置 在烧结炉中烧结铂球并形成完成的电极。
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公开(公告)号：US5350404A
公开(公告)日：1994-09-27
申请号：US130308
申请日：1993-10-01
CPC分类号： A61N1/3918 , A61N1/056 , A61N1/0563 , A61N1/3956 , A61N1/3962 , A61N1/395 , A61N1/3987 , A61N2001/0585
摘要： An implantable atrial defibrillator provides a pulse of defibrillating electrical energy to the atria of the heart in synchronism with sensed R waves in response to non-coincident sensing of an R wave at first and second areas of the heart. The defibrillating pulse is provided after a predetermined number of consecutive R waves are non-coincidently sensed to assure reliable synchronization. The atrial defibrillator is also operational in a marker mode wherein a number of synchronization marker pulses are delivered to the heart for detection on an externally generated electrocardiogram. The atrial fibrillation detector of the defibrillator is normally disabled and is activated when the sensed ventricular activity indicates a probability of atrial fibrillation to conserve a depletable power source. A plurality of lead systems are also described for use with the atrial defibrillator which reduce the quantity of electrical energy required to defibrillate the heart and ensure that the delivered atrial defibrillating electrical energy is substantially confined to the atria of the heart.
摘要翻译： 可植入心房除颤器响应于在心脏的第一和第二区域处的R波的不一致的感测，与感测到的R波同步地向心脏的心房提供除颤电脉冲。 在不一致地感测到预定数量的连续R波之后提供除颤脉冲，以确保可靠的同步。 心房除颤器还可以在标记模式中操作，其中多个同步标记脉冲被传送到心脏以便在外部产生的心电图上进行检测。 除颤器的心房颤动检测器通常被禁用，并且当感测到的心室活动指示心房颤动的概率以节省可消耗的电源时被激活。 还描述了与心房除颤器一起使用的多个引导系统，其减少了除颤心脏所需的电能的量，并确保输送的心房除颤电能基本上限于心脏的心房。
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10.发明授权Ring electrode for a multilumen lead and method of constructing a multilumen lead 失效用于多腔铅的环形电极和构建多腔铅的方法
公开(公告)号：US5330522A
公开(公告)日：1994-07-19
申请号：US997804
申请日：1992-12-29
申请人： Paul E. Kreyenhagen
发明人： Paul E. Kreyenhagen
CPC分类号： A61N1/056
摘要： An implantable pacing lead for use with a cardiac pacemaker having a multilumen tubing for the lead body and at least one ring electrode or electrical contact located between the distal and proximal ends of the pacing lead. The ring electrode includes axially aligned bores therethrough, the bores corresponding to the locations of the lumens within the multilumen tubing. A stabilizing element assures that the interconnection between the multilumen tubing and the cylindrical electrode is secure.
摘要翻译： 一种用于心脏起搏器的植入式起搏引线，其具有用于引线主体的多腔管和位于起搏引线的远端和近端之间的至少一个环形电极或电触点。 环形电极包括穿过其中的轴向对齐的孔，孔对应于多个管内管腔的位置。 稳定元件确保多腔管和圆柱形电极之间的互连是牢固的。
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