Abstract:
A blood processing system comprises a processing chamber to process blood and a fluid flow cassette that communicates with the processing chamber. The cassette comprises a body, a pump chamber formed in the body, and a flexible diaphragm on the pump chamber responsive to an applied fluid pressures for flexure toward and away from the pump chamber to pump fluid through the pump chamber. The cassette also includes a flow path formed, at least in part, in the body to couple the pump chamber in fluid flow communication with the processing chamber, to convey fluid pumped by the pump chamber into the processing chamber. The cassette also includes an in line cavity formed in the body and located in the flow path to trap air to prevent entry of air into the processing chamber.
Abstract:
Systems and related methods pump fluid through a pump. The pump comprises a pump chamber, which is responsive to applied pressures to convey fluid. The systems and methods place an electrode in electrical conductive contact with fluid in the pump chamber which, in use, is coupled to an electrical source. The electrode generates an electrical field in the pump chamber that varies according volume of fluid in the pump chamber. The systems and methods register variations in the electrical field as fluid is conveyed through the pump chamber.
Abstract:
A method for centrifugally separating whole blood into red blood cells and a plasma constituent rotates about a rotational axis a separation zone having radially spaced apart walls with a high-G side and a low-G side located closer to the rotational axis than the high-G side. Whole blood enters the rotating separation zone in an entry region to begin separation. Separation is halted by a terminal wall that is circumferentially spaced from the entry region. The whole blood separates into red blood cells toward the high-G side and plasma constituent toward the low-G side. The method directs red blood cells separated in the separation zone in a circumferential flow direction toward the terminal wall. The method directs separated red blood cells from the rotating separation zone through a second path that extends, at least in part, radially beyond the high-G wall.
Abstract:
A yoke rotates an umbilicus about a rotational axis, which, in turn, imparts rotation to a blood processing chamber coupled to the umbilicus. The yoke carries first and second umbilicus support surfaces that inhibit travel of the umbilicus in radial directions toward and away from the rotational axis.
Abstract:
A blood separation chamber comprises a base that includes formed walls that define a hub. A separation channel extends about the hub. A flow passage extends between the hub and the separation channel. The hub enables attachment of external tubing to convey blood to and from the separation channel through the hub.
Abstract:
Blood component processing systems and methods are adapted to be coupled to a blood component processing device. The systems and methods employ a fluid circuit comprising at least one fluid pressure actuated pump station, at least one fluid flow path communicating with the pump station, and at least one valve in the fluid flow path. A control module sized and configured to interact with the fluid circuit includes an actuator to selectively apply fluid pressure to the pump station in concert with operation of the valve to pump fluid through the fluid flow path in response to a control program. A circuit board assembly is associated with the actuator in electrical conductive interaction with fluid in the pump station. The circuit board assembly comprises a part of a capacitive sensing circuit. The circuit board assembly can comprise, e.g., a printed circuit board assembly, or a flexible circuit, or a molded circuit. The circuit board assembly can, e.g., be face-mounted on the actuator or comprise an integrated component of the actuator.
Abstract:
An adaptable blood processing platform comprises a blood processing device and a ground engaging frame including a shelf to which the blood processing device is secured. The frame supports the shelf for movement between a lowered position and a raised position. The shelf can be supported, e.g., for swinging cantilevered movement about an axis between the lowered and raised positions. The shelf can be supported, e.g., by a scissors linkage assembly coupled to the shelf for lowering and lifting the shelf between a lowered and raised positions. In the lowered position, the center of gravity of the blood processing device is located a first distance above ground, which is conducive for stable storage and/or transport of the platform. In the raised position, the center of gravity of the blood processing device is located a second distance above ground greater than the first distance, which is conductive for set-up and operation of the platform.
Abstract:
A blood separation chamber comprises a base that includes formed walls that define a hub. A separation channel extends about the hub. A flow passage extends between the hub and the separation channel. The hub enables attachment of external tubing to convey blood to and from the separation channel through the hub.
Abstract:
A blood separation assembly comprises a blood processing chamber having a base including formed walls that define a separation channel. A centrifuge rotor is rotatable about a rotational axis. A latch assembly comprises a latch arm that is pivotally mounted on the centrifuge rotor. The latch arm can be moved between a chamber-retaining position engaging the blood processing chamber, to secure the blood processing chamber to the centrifuge rotor, and a chamber- releasing position free of engagement with the blood processing chamber, to enable removal of the blood processing chamber from the centrifuge rotor. The latch assembly also includes a pawl movable on the centrifuge rotor between a first position adjacent the latch arm and a second position spaced from the latch arm. The pawl includes a locking element that engages the latch arm when the latch arm is in the chamber-retaining position, to resist movement of the latch arm toward the chamber-releasing position. A spring biases the pawl toward the first position.