公开(公告)号：US11623944B2

公开(公告)日：2023-04-11

申请号：US16669783

申请日：2019-10-31

Applicant: Bayer CropScience LP

Inventor： Jeremy Beau ,  Daniel M. Joo ,  Patrick Schwientek ,  Colleen S. Taylor ,  Bjorn A. Traag

IPC: C07K11/02 ,  C12N9/00 ,  C07K14/195 ,  A01N63/25 ,  C12N1/20 ,  C12N9/90 ,  C12R1/01

Abstract: The present invention relates to a composition comprising a biologically pure culture of a fungicidal Paenibacillus sp. strain comprising a variant fusaricidin synthetase lacking a functional adenylation domain in the third module. The present invention also provides a composition comprising a biologically pure culture of a fungicidal Paenibacillus sp. strain or a cell-free extract thereof comprising at least one Paeniserine and at least one Paeniprolixin. Also provided are isolated compounds and methods of treating a plant to control a plant disease with the disclosed compositions and compounds.

公开(公告)号：US12173278B2

公开(公告)日：2024-12-24

申请号：US17054951

申请日：2019-05-08

Applicant: Bayer CropScience LP

Inventor： Jennifer Anne Collins ,  Jesus F. Sanchez ,  James L. Waller ,  Bjorn A. Traag ,  Sara K. Hotton ,  Tony J. Tegeler

IPC: C12N1/20 ,  A01N63/25 ,  C07K14/195 ,  C12R1/01

Abstract: The present invention provides a composition comprising a biologically pure culture of a Paenibacillus sp. strain comprising a mutant DegU lacking a functional receiver domain or a functional DNA binding domain and/or a mutant DegS lacking a functional single binding domain or a functional ATPase domain with decreased viscosity in a liquid culture. Also provided is a method of identifying a Paenibacillus sp. mutant derivative strain with decreased viscosity in a liquid culture compared to a Paenibacillus sp. parental strain with a visual screen for mutant isolates with a non-mucoid morphology.

公开(公告)号：US10159257B2

公开(公告)日：2018-12-25

申请号：US15874577

申请日：2018-01-18

Applicant: Bayer CropScience LP

Inventor： Jeremy Beau ,  Daniel M. Joo ,  Patrick Schwientek ,  Colleen S. Taylor ,  Bjorn A. Traag

IPC: A01N63/02 ,  C12N9/90 ,  A01N63/00 ,  C12N9/00 ,  C07K14/195 ,  C12R1/01

Abstract: The present invention relates to a composition comprising a biologically pure culture of a fungicidal Paenibacillus sp. strain comprising a variant fusaricidin synthetase lacking a functional adenylation domain in the third module. The present invention also provides a composition comprising a biologically pure culture of a fungicidal Paenibacillus sp. strain or a cell-free extract thereof comprising at least one Paeniserine and at least one Paeniprolixin. Also provided are isolated compounds and methods of treating a plant to control a plant disease with the disclosed compositions and compounds.

公开(公告)号：US10988769B2

公开(公告)日：2021-04-27

申请号：US16191964

申请日：2018-11-15

Applicant: Bayer CropScience LP

Inventor： Damian Curtis ,  Benjamin L. Golomb ,  Dilara Ally ,  Florencia A. Ficarra ,  Rauf Salamzade ,  Bjorn A. Traag

IPC: C12N15/74 ,  C12N9/04 ,  C07K14/325 ,  C12N9/24 ,  C12N9/42 ,  A01N63/00 ,  C07K14/195 ,  C12N11/16 ,  C12N15/62 ,  C12N1/20 ,  C12N15/10 ,  A01N63/10

Abstract: Signal sequences useful for targeting proteins and peptides to the surface of endospores produced by Paenibacillus family members and methods of using the same are provided. The display of heterologous molecules, such as peptides, polypeptides and other recombinant constructs, on the spore surface of Paenibacillus family members, using particular N-terminal targeting sequences and derivatives of the same, are also provided.

公开(公告)号：US09883676B2

公开(公告)日：2018-02-06

申请号：US15078670

申请日：2016-03-23

Applicant: Bayer CropScience LP

Inventor： Jeremy Beau ,  Daniel M. Joo ,  Patrick Schwientek ,  Colleen S. Taylor ,  Bjorn A. Traag

IPC: C12N1/20 ,  A01N63/02 ,  C12N9/90 ,  A01N63/00 ,  C12N9/00 ,  C12R1/01 ,  C07K14/195

CPC classification number: A01N63/02 ,  A01N63/00 ,  C07K14/195 ,  C12N9/90 ,  C12N9/93 ,  C12R1/01

Abstract: The present invention relates to a composition comprising a biologically pure culture of a fungicidal Paenibacillus sp. strain comprising a variant fusaricidin synthetase lacking a functional adenylation domain in the third module. The present invention also provides a composition comprising a biologically pure culture of a fungicidal Paenibacillus sp. strain or a cell-free extract thereof comprising at least one Paeniserine and at least one Paeniprolixin. Also provided are isolated compounds and methods of treating a plant to control a plant disease with the disclosed compositions and compounds.